Archiv: messenger ribonucleic acid (mRNA) molecule

12.08.2020 - 19:18 [ ]

Forbidden Op-Ed: The Sputnik Vaccine as a Lifesaving Global Partnership

The use of two vectors is the unique technology, developed by the Gamaleya Center scientists, which differentiates the Russian vaccine from other adenoviral vector-based vaccines under development around the world. Vaccines based on adenoviral vectors also have clear advantages over other technologies such as mRNA vaccines.

Prospective mRNA vaccines, undergoing clinical trials in the United States and other countries, do not use vectors for delivery and represent an RNA molecule with coronavirus protein code wrapped in a lipid membrane. This technology is promising but its side effects, especially an impact on fertility, have not yet been studied in depth. No mRNA vaccine has yet received regulatory approval in the world.

12.08.2020 - 19:17 [ ]

Impfstoff gegen Covid-19: Russlands Gesundheitsminister nennt Frist von Produktion erster Packungen

„Wenn wir zum Beispiel vom RNA-Impfstoff sprechen, der in anderen Ländern produziert wurde, gab es dann Publikationen – diese können Sie finden, wonach ein Teil der Impfstoffe ohne präklinische Forschungen erschienen ist und sofort bei Menschen eingesetzt worden ist, was in unserem Fall ausdrücklich nicht der Fall ist.“

28.07.2020 - 06:47 [ ]

Chancen und Gefahren der Gen-Impfstoffe


Im Gegensatz zu DNA-Impfstoffen werden RNA-Impfstoffe nicht in den Zellkern transportiert. Daher besteht auch nicht die theoretische Gefahr, dass diese in das Erbgut von Körperzellen integriert wird. Theoretisch wäre es möglich, dass andere bereits im Körper vorhandene Viren die Impf-RNA in DNA „umschreiben“, so dass diese sich doch in das Erbgut einer Zelle integrieren und dort Folgeschäden auslösen könnte. Eine solche Umschreibung wird jedoch nicht beobachtet.

28.07.2020 - 06:43 [ MDR ]

Können m-RNA-Impfungen Menschen mutieren lassen?


Gegen Corona werden erstmals RNA-Impfstoffe erprobt. Dabei wollen Mediziner ihren Patienten ein kleines Stückchen Erbinformation spritzen, die in den menschlichen Zellen die Produktion des Antigens von Sars-CoV-2 auslöst. Das Antigen ist praktisch ein Erkennungsmolekül des Virus und zugleich eine Art Schlüssel, mit dem es in die Zelle eindringt. Produziert eine Zelle diese Antigene, zeigt sie diese auch auf der Zellhülle.

20.07.2020 - 17:39 [ Bloomberg ]

U.K. Orders 90 Million Vaccine Doses from Pfizer and Valneva

“It’s the right thing to be doing to be at the absolute front of the queue to make sure we’re in a position to get those vaccines first when they become available,” Education Secretary Gavin Williamson told the BBC during the government’s media round on Monday.

11.07.2020 - 18:33 [ ]

Why the Bill Gates global health empire promises more empire and less public health

Behind a veil of corporate media PR, the Gates Foundation has served as a vehicle for Western capital while exploiting the Global South as a human laboratory. The coronavirus pandemic is likely to intensify this disturbing agenda.

16.03.2020 - 15:10 [ ]

Battle of the Biotech Unicorns: CureVac vs. Moderna


But despite being competitors, the companies’ CEOs seem to have quite a good relationship and consider each other collaborators rather than enemies. Every year, they organize an mRNA conference together that takes turns between Boston and Berlin to bring together all the stakeholders in the field. It was at this year’s edition, in Berlin, that I had the chance to bring them together for an interview regarding the future of mRNA therapies.

16.03.2020 - 14:55 [ Fox News ]

Coronavirus: Biotech company ships first batches of vaccine, to be tested on humans: report

The trials will be held at Kaiser Permanente Washington Health Research Institute in Seattle. Testing will involve 45 young, healthy volunteers and it uses Moderna’s mRNA-1273 vaccine.

„Unlike a normal vaccine, RNA vaccines work by introducing an mRNA sequence (the molecule which tells cells what to build) which is coded for a disease-specific antigen, once produced within the body, the antigen is recognized by the immune system, preparing it to fight the real thing,“ according to the University of Cambridge.

16.03.2020 - 14:53 [ ]

CureVac works on mRNA vaccine for coronavirus

Since 2006, the company has been manufacturing mRNA-based vaccines and therapeutics. It is currently looking to boost its manufacturing capacity to supply up to billions of doses during outbreaks.

CureVac chief technology officer Mariola Fotin-Mleczek said: “Nature has invented mechanisms to activate our immune system against infectious diseases. With our unique messenger RNA technology, we mimic nature and give our body the information on how to fight against the virus.

16.03.2020 - 10:15 [ ]

Moderna : Germany tries to halt U.S. interest in firm working on coronavirus vaccine

CureVac in 2015 and 2018 secured financial backing for development projects from its investor the Bill & Melinda Gates Foundation, working on shots to prevent malaria and influenza.

In the field of so-called mRNA therapeutics, CureVac competes with U.S. biotech firm Moderna and German rival BioNTech, which Pfizer has identified as a potential collaboration partner.