Archiv: Moderna (corporation)


06.09.2021 - 18:45 [ LibTee / Twitter ]

Local COVID cases up 163% in four weeks, breakthrough infections one third of cases statewide last month | Local News |

(Sep 4, 2021)

06.09.2021 - 18:35 [ Boston25News.com ]

COVID breakthrough infections soar in Massachusetts

(August 10, 2021)

“The vaccines are 95 percent effective, not a hundred percent,” said William Schaffner, MD, an infectious disease and vaccine specialist at Vanderbilt University in Nashville, Tennessee. “We know that many of those people, older already, probably had serious underlying illnesses. Then if COVID hits you on top of that — that may be sufficient to graduate you to heaven.”

06.09.2021 - 18:31 [ StarTribune.com ]

Breakthrough COVID-19 cases accelerate in Minnesota

(30.08.2021)

State health officials said a higher proportion of breakthrough infections was inevitable as more people received shots and the coronavirus had fewer unvaccinated people left to target.

06.09.2021 - 17:51 [ Deadline.com ]

In Los Angeles, Breakthrough Infections Are Now 30% Of All New Covid Cases Amid Delta Surge

(August 19, 2021)

In March 2021, when Americans first began hearing about the Delta variant of Covid-19, breakthrough infections among fully-vaccinated Angelenos accounted for just 2% of that month’s case total. By June, when Delta accounted for 50% of all variants in Los Angeles, breakthrough infections among fully-vaccinated residents had risen to 20% of all identified cases. In late July, county officials reported that the Delta variant had overwhelmed all others, accounting for more than 90% of all positive tests analyzed for variants. As a result, the ratio of breakthrough cases increased to 30%, local health officials announced today.

29.08.2021 - 13:51 [ France24 ]

Japan detects more Moderna vaccine contamination

Japan’s Okinawa region suspended the use of Moderna’s Covid-19 vaccine on Sunday after another contamination was spotted, the local government said.

It comes a day after the Japanese health ministry said it was investigating the death of two men who received shots from tainted Moderna batches — though the cause of their death is unknown.

29.08.2021 - 05:40 [ NBC San Diego ]

FDA to Add Warning to Pfizer, Moderna Vax After CDC Finds ‘Likely‘ Link With Rare Heart Condition

(June 24, 2021)

Pfizer and Moderna vaccine fact sheets will soon feature a label from the Food and Drug Administration (FDA) warning of a heart inflammation risk in adolescents and young adults after a Centers for Disease Control and Prevention (CDC) safety panel determined there is a „likely association“ between the vaccines and cases of myocarditis and pericarditis in younger vaccine recipients, according to an analysis presented by the panel Wednesday.

The CDC says the findings do not change the basic recommendation that all people 12 and older should be vaccinated …

29.08.2021 - 05:33 [ theSun.co.uk ]

Covid vaccines linked to four different skin reactions – from hives to swelling

(23 Jun 2021)

It may appear on one part of the body or be spread across large areas. The rash is usually very itchy and ranges in size from a few millimetres to the size of a hand.

Others suffered from swelling or angioedema, which is the swelling of areas of tissue under the skin, sometimes affecting the face and throat.

The study looked at Pfizer and Moderna jabs, which have the same messenger RNA process.

29.08.2021 - 04:33 [ Japan Today ]

Japan probes two deaths after jabs from tainted Moderna batch

Both men contracted fever after receiving their vaccinations and neither had underlying health conditions or allergic history, the ministry said.

The suspension affects 1.63 million doses of Moderna COVID vaccines, which have been reportedly shipped to over 800 vaccination centers across Japan.

29.08.2021 - 04:20 [ Japan Today ]

Japan halts use of 1.63 mil Moderna vaccine doses over contamination

The foreign substances have been confirmed since Aug. 16 at eight vaccination sites in five prefectures — Ibaraki, Saitama, Tokyo, Gifu and Aichi. They were found in a total of 39 vials.

Takeda reported them to the ministry on Wednesday.

The composition of the foreign matter, a few millimeters in size, has not been determined.

The „small black materials“ reported to the ministry could be metallic fragments, one of its senior officials said.

12.08.2021 - 11:15 [ Yahoo.com ]

Moderna, BioNTech Plunge As EU Studies Possible Side-effects Of mRNA Shots

The conditions were reported in patients who took the mRNA vaccines made by either Moderna or BioNTech-Pfizer.

Pfizer stock fell 3%.

12.08.2021 - 11:03 [ Finanzen.ch ]

Moderna- und BionNTech-Aktien fallen nach EMA-Prüfung zweistellig – auch Pfizer schwach

Wie an diesem Mittwoch in einem regelmässig der Öffentlichkeit zugänglich gemachten Routinebericht veröffentlicht, prüft die europäische Arzneimittelbehörde (EMA) aktuell, ob aufgetretene seltene Symptome nach der Verabreichung von mRNA-Impfstoffen gegen COVID-19 als Nebenwirkung eingestuft werden sollen.

12.08.2021 - 11:02 [ BR.de ]

EMA-Datenbank zeigt keine bestätigten Impf-Nebenwirkungen

(09.08.2021)

Impfskeptiker führen häufig Zahlen der Europäischen Medizinagentur (EMA) an, wenn sie auf angebliche Gefahren der Impfung hinweisen. Doch die Meldungen in der EMA-Datenbank sind keine bestätigten Nebenwirkungen. Ein #Faktenfuchs.

12.08.2021 - 10:50 [ Achse des Guten ]

Warum ist der Impfstoff klinisch nicht wirksam?

In keiner Studie ist es Pfizer/BioNTech (oder Moderna, AstraZeneca und Johnson&Johnson) gelungen, irgendeine Wirksamkeit der Impfung gegen den Tod an COVID oder eine klinisch relevante Wirksamkeit gegen schwere Verläufe zu zeigen. Im Folgenden zeige ich anhand der neuesten Pfizer-Studie noch einmal Schritt für Schritt, warum das so ist.

28.07.2021 - 08:17 [ ORF.at ]

WTO weiter uneins über Aussetzung der Impfstoffpatente

Pharmakonzerne und die Länder, in denen sie angesiedelt sind, argumentieren, Patente seien nicht das Haupthindernis bei der Erhöhung der Produktion. Zugleich warnen sie, dadurch würden Innovationen ausgebremst. Die 164 WTO-Staaten müssen alle Entscheidungen im Konsens treffen.

28.07.2021 - 08:12 [ UrduPoint.com ]

WTO Members Fail To Agree On Patent Waiver For COVID-19 Vaccines

The World Trade Organization member countries have failed to reach a consensus on a temporary waiver of intellectual property rights for COVID-19 vaccines, WTO spokesman Keith Rockwell said on Tuesday following the General Council session. According to Okonjo-Iweala, the WTO member countries will make a decision by the 12th WTO ministerial conference, which will take place in late November-early December.

14.07.2021 - 06:54 [ theGuardian.com ]

Pfizer pushes for US booster shots as WHO says greed is driving vaccine disparities

Dr Soumya Swaminathan, the chief WHO scientist, said: “At this point … there is no scientific evidence to suggest that boosters are definitely needed.”

Swaminathan said the WHO would make recommendations on booster shots “based on the science and data, not on individual companies declaring that the vaccines should now be administered as a booster dose”.

14.07.2021 - 06:48 [ Blick.ch ]

Dritte Auffrischungsimpfung gilt als fragwürdig: WHO wirft Impfstoff-Herstellern Gier vor

Der US-Pharmakonzern Pfizer hat am Montag eine Genehmigung für dritten Dosen seines Covid-19-Impfstoffs beantragt. Das erntete scharfe Kritik von der Weltgesundheitsorganisation (WHO). Deren Vorsitzender Tedros Adhanom Ghebreyesus (56) warf dem Pharmamulti Gier vor. Impfstoff-Hersteller sollten weniger wohlhabende Länder bevorzugen, statt fragwürdige Auffrischungsimpfungen in reichen, bereits gut durchgeimpften Ländern anzustreben.

30.06.2021 - 17:59 [ DailyMail.co.uk ]

Gloomy SAGE adviser calls for Freedom Day to be delayed until all children are vaccinated – which could take THREE MORE months – despite hospital and death rates flatlining

The vaccine rollout is expected to drop to 150,000 first doses a day in the next few months because of shortages in the supply of Pfizer and Moderna’s jabs and because the AstraZeneca vaccine is not being given to young people.

27.05.2021 - 11:49 [ NBC News ]

CDC looking into possible link between heart problem and Covid vaccines in young people

(24.05.2021)

The CDC did not respond to questions about the exact number of reports. However, NBC News identified at least 55 suspected cases nationwide.

That number includes 14 cases under investigation by the Department of Defense among members of the military, but it may be an underestimate. And some, but not all, state departments of health are tracking such cases.

27.05.2021 - 11:48 [ CNN ]

Covid-19 vaccine isn’t linked to heart problems in young people — but doctors still worry parents will be scared to vaccinate their children

(25.05.2021)

Pediatricians worry parents will misinterpret a finding by advisers to the US Centers for Disease Control and Prevention and become scared — for no reason — to vaccinate their children against Covid-19.

16.05.2021 - 18:12 [ BZ Berlin B.Z. / Twitter ]

Rund 13.000 Corona-Infektionen bei vollständig Geimpften

(14.05.2021)

08.05.2021 - 07:45 [ FAZ Topthemen / Twitter ]

Viel spricht dafür, dass Geimpfte das Virus kaum noch verbreiten können. Macht es dabei einen Unterschied, welcher Impfstoff verabreicht wurde? Es fehlt an Daten.

(05.05.2021)

08.05.2021 - 07:15 [ Vienna.at ]

Wohl dritte Impfung mit BioNTech/Pfizer nötig

(16.04.2021)

„Ein wahrscheinliches Szenario ist, dass es die Notwendigkeit einer dritten Dosis geben wird, irgendwo zwischen sechs und zwölf Monaten, und danach eine jährliche Neu-Impfung, aber all das muss noch bestätigt werden“, sagte der Vorstandsvorsitzende des US-Pharmakonzerns dem US-Sender CNBC in einem am Donnerstag veröffentlichten, aber bereits Anfang April geführten Interview.

08.05.2021 - 07:09 [ Max Brand / Twitter ]

Was der Bundestag nicht alles beschließen kann…: „Nach der vom Bundestag beschlossenen Corona-Verordnung sollen Geimpfte unbefristet immun sein, Genesene hingegen nur sechs Monate.“

07.05.2021 - 09:06 [ Christiane Eff (formerly known as NotHeidisClown) / Twitter ]

Das die #Patentfreigabe überhaupt diskutiert wird zeigt wie bankrott und verkommen das Wertesystem ist Pfizer hat 2018 11,1 Mrd $ und 2019 16,2 Mrd $ Gewinn gemacht. Man sollte fragen warum der Konzern nicht von sich aus auf den Schutz der Patente verzichtet

07.05.2021 - 09:00 [ ZDF ]

Debatte um Patent-Aussetzung – Steutel: „Verheerende Folgen für Deutschland“

Deutsche Pharma-Firmen lehnen den Vorschlag von US-Präsident Biden, Patentrechte auszusetzen rundweg ab. Niemand könne in weniger als sechs Monaten eine Produktion hochziehen, betont der Chef des Verbandes Forschender Arzneimittelhersteller (vfa) im ZDF.

07.05.2021 - 00:24 [ Tagesschau,de ]

++ Bundesregierung: Patentschutz notwendig ++

Auch Bundesentwicklungsminister Gerd Müller steht dem Vorstoß aus Washington für die Freigabe von Impfstoff-Patenten skeptisch gegenüber. „Nur ein Patent freizugeben, sorgt noch für keine einzige zusätzliche Impfdose“, sagte er dem „Spiegel“. „Das Patent allein reicht nicht. Man muss auch wissen, wie produziert werden soll.“

07.05.2021 - 00:19 [ Yahoo.com ]

Pfizer, Moderna shares plummet after Biden administration backs a COVID-19 vaccine patent waiver

The Biden administration „believes strongly in intellectual property protections,“ Tai said in a statement, but the White House will back the waiver given the „extraordinary circumstances of the COVID-19 pandemic.“ The administration has faced pressure to support the measure, which is aimed at increasing vaccinations around the world — especially in countries experiencing a surge in infections, like India — without having to rely solely on exports.

30.04.2021 - 06:32 [ i24news.tv ]

Israel’s COVID restrictions may end in 3 weeks, deputy health minister says

The deputy minister added that from next week, those people with a „Green Pass“ – either having received both vaccines or recovered from coronavirus – would be „more or less restriction-free.“

28.04.2021 - 06:11 [ New York Times ]

Can Vaccinated People Spread the Virus? We Don’t Know, Scientists Say.

(01.04.2021)

The Centers for Disease Control and Prevention on Thursday walked back controversial comments made by its director, Dr. Rochelle P. Walensky, suggesting that people who are vaccinated against the coronavirus never become infected or transmit the virus to others.

28.04.2021 - 06:09 [ 10tv.com ]

CDC says fully vaccinated Americans can go outside without a mask

Some experts portrayed the relaxed guidance as a reward and a motivator for more people to get vaccinated — a message President Joe Biden sounded, too.

“The bottom line is clear: If you’re vaccinated, you can do more things, more safely, both outdoors as well as indoors,” Biden said.

28.04.2021 - 05:54 [ Peace Love / Twitter ]

„Es muss davon ausgegangen werden, dass Menschen nach Kontakt mit dem Virus trotz Impfung symptomatisch oder asymptomatisch infiziert werden können und dabei das Virus Sars-CoV-2 ausscheiden.“

(17.04.2021)

27.04.2021 - 05:10 [ Peace Love / Twitter ]

„Es muss davon ausgegangen werden, dass Menschen nach Kontakt mit dem Virus trotz Impfung symptomatisch oder asymptomatisch infiziert werden können und dabei das Virus Sars-CoV-2 ausscheiden.“

(17.04.2021)

27.04.2021 - 05:06 [ MDR.de ]

Mitteldeutschland: Mehr als 400 Coronafälle trotz zweimaliger Impfung

(15.04.2021)

Auf dieses Restrisiko weisen auch die Experten vom Paul-Ehrlich-Institut hin. Auf Anfrage von MDR AKTUELL heißt es schriftlich: „Es muss davon ausgegangen werden, dass Menschen nach Kontakt mit dem Virus trotz Impfung symptomatisch oder asymptomatisch infiziert werden können und dabei das Virus Sars-CoV-2 ausscheiden.“

Deswegen solle man sich auch nach der Impfung weiter an die allgemein geltenden Schutzmaßnahmen halten, schreibt das Institut weiter. „Im Moment ist der Erkenntnisstand, dass die Impfung keine vollständig sterile Immunität verursacht.“

27.04.2021 - 05:04 [ RND / Twitter ]

Laut #RKI spielen geimpfte Personen keine wesentliche Rolle mehr für das Infektionsgeschehen. Thüringens Ministerpräsident #Ramelow (Linke) fordert, dass Geimpfte jetzt auch gleich behandelt werden sollten wie Menschen mit einem negativen Testergebnis.

(13.04.2021)

27.04.2021 - 05:01 [ tagesschau / Twitter ]

RKI: Doppelt Geimpfte wohl keine Überträger mehr

(04.04.2021)

#Spahn #Corona #Impfung #Freiheit

26.04.2021 - 06:46 [ New York Times ]

Can Vaccinated People Spread the Virus? We Don’t Know, Scientists Say.

(01.04.2021)

The Centers for Disease Control and Prevention on Thursday walked back controversial comments made by its director, Dr. Rochelle P. Walensky, suggesting that people who are vaccinated against the coronavirus never become infected or transmit the virus to others.

26.04.2021 - 06:25 [ CNN ]

Fully vaccinated Americans will be able to vacation in the EU this summer, European Commission president tells New York Times

Data from the US Centers for Disease Control and Prevention indicates about 28% of Americans are now fully vaccinated — meaning it has been two weeks since their second dose of the Moderna or Pfizer vaccine, or a week since their Johnson & Johnson single-shot vaccine.

12.03.2021 - 08:48 [ Tagesschau.de ]

Johnson & Johnson: Warum punktet der neue Impfstoff?

Damit ist die Wirkungsweise von Johnson & Johnson die gleiche, wie die des Impfstoffs von AstraZeneca, nur dass beide unterschiedliche Trägerviren verwenden.

Bei den neuartigen mRNA-Impfstoffen von BioNTech/Pfizer und Moderna werden hingegen keine Viren oder Teile von Viren geimpft, sondern direkt ein Teil des Coronavirus-Erbgutes. Diese genetische Information funktioniert wie ein Bauplan

07.03.2021 - 20:35 [ ORF.at ]

Knapper Impfstoff: EU wendet sich an die USA

Brüssel will konkret über die Lieferung von US-Produkten verhandeln, die für die Herstellung von Impfstoffen benötigt werden, aber strikten Exportbeschränkungen unterliegen.

Bei den Beratungen soll es unter anderem um spezielle Taschen für Impfstoffbehältnisse gehen, die vor allem von US-Unternehmen in der EU sowie von europäischen Unternehmen in den USA hergestellt werden. Thema sollen außerdem Ampullen, Spritzen und Lipidnanopartikel sein, die zur Verkapselung von mRNA-Impfstoffen benötigt werden.

07.03.2021 - 10:47 [ Radio Utopie ]

Wozu Impfpässe, wenn man nach wie vor den Virus bekommen und Andere anstecken kann?

(21.01.2021)

Alle müssen wissen, dass die in der „Europäischen Union“ zugelassenen Impfstoffe der Konzerne Pfizer / BioNTech und Moderna keine sterilisierende Immunität liefern. Nochmal: das heisst, dass diese sogenannten „Impfstoffe“ weder vor Infektion von SARS II (dem aktuellen Coronavirus), noch vor dessen Verbreitung schützen, sondern lediglich den Angaben zufolge gegen die von SARS II ausgelöste Krankheit Covid-19; und dies auch nur für eine unklare Zeitperiode. Eine Immunität gegen SARS II gibt es durch diesen Impfstoff also nicht.

25.02.2021 - 08:07 [ New York Times ]

As Israel Reopens, ‘Whoever Does Not Get Vaccinated Will Be Left Behind’

(18.02.2021)

New government and business initiatives are moving in the direction of a two-tier system for the vaccinated and unvaccinated, raising legal, moral and ethical questions.

23.02.2021 - 11:19 [ Reuters ]

Israeli studies find Pfizer COVID-19 vaccine reduces transmission

(19.02.2021)

Findings of the pre-published study, not yet peer-reviewed, but based on a national database that is one of the world’s most advanced, were first reported by the Israeli news site Ynet late on Thursday and were obtained by Reuters on Friday.

Pfizer declined to comment and the Israeli Health Ministry did not respond to a request for comment.

23.02.2021 - 11:15 [ theGuardian.com ]

Covid: vaccinated Israelis to enjoy bars and hotels with ‘green pass’

(19.02.2021)

Israel is preparing itself to be split in half from next week, with the government creating a new privileged tier in society: the vaccinated.

23.02.2021 - 11:14 [ Radio Utopie ]

Wozu Impfpässe, wenn man nach wie vor den Virus bekommen und Andere anstecken kann?

(21.01.2021)

Alle müssen wissen, dass die in der „Europäischen Union“ zugelassenen Impfstoffe der Konzerne Pfizer / BioNTech und Moderna keine sterilisierende Immunität liefern. Nochmal: das heisst, dass diese sogenannten „Impfstoffe“ weder vor Infektion von SARS II (dem aktuellen Coronavirus), noch vor dessen Verbreitung schützen, sondern lediglich den Angaben zufolge gegen die von SARS II ausgelöste Krankheit Covid-19; und dies auch nur für eine unklare Zeitperiode. Eine Immunität gegen SARS II gibt es durch diesen Impfstoff also nicht.

11.02.2021 - 09:54 [ Tagesschau.de ]

113 Menschen nach Impfung verstorben: Fachleute geben dennoch Entwarnung

In einigen Senioreneinrichtungen kam es zudem kurz nach der Impfung zu Corona-Ausbrüchen. In einem Alten- und Pflegeheim in Leverkusen starben 18 Bewohnerinnen und Bewohner, auch in Uhldingen-Mühlhofen am Bodensee starben bereits Geimpfte an dem Virus. Sie waren wohl schon zum Zeitpunkt der Impfung unerkannt infiziert oder die Infizierung hat kurz danach stattgefunden.

09.02.2021 - 20:57 [ theGuardian.com ]

How can Covid vaccines be tweaked to tackle new variants?

Production BioNTech has said it can produce a fresh vaccine within six weeks of a decision being made. But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce

07.02.2021 - 22:52 [ ChildrensHealthDefense.org ]

501 Deaths + 10,748 Other Injuries Reported Following COVID Vaccine, Latest CDC Data Show

As of Jan. 29, about 35 million people in the U.S. had received one or both doses of a COVID vaccine. So far, only the Pfizer and Moderna vaccines have been granted Emergency Use Authorization in the U.S. by the U.S. Food and Drug Administration (FDA). By the FDA’s own definition, the vaccines are still considered experimental until fully licensed.

According to the latest data, 453 of the 501 reported deaths were in the U.S. Fifty-three percent of those who died were male, 43% were female, the remaining death reports did not include the gender of the deceased. The average age of those who died was 77, the youngest reported death was of a 23-year-old. The Pfizer vaccine was taken by 59% of those who died, while the Moderna vaccine was taken by 41%.

07.02.2021 - 22:46 [ DailyMail.co.uk ]

Californian dies hours after receiving COVID vaccine as investigation into cause of death gets underway

(24.01.2021)

– They had tested positive for COVID-19 in late December, but died hours after receiving a dose of the vaccine, local officials said
– It’s unclear if the person was given the Moderna or Pfizer vaccine
– Police say the person’s death is being investigated with an autopsy due Monday
– Dr. Dean Blumberg, an infectious disease expert at UC Davis Children’s hospital, said he believes the person’s death is ‚probably not related to the vaccine‘

07.02.2021 - 21:15 [ KTOO.org ]

Juneau nursing home outbreak could be a model for what COVID-19 looks like after vaccine

(07.02.2021)

Staff and outside experts attribute the health of these people in the face of their COVID-19 infections primarily to the Pfizer and Moderna vaccines. Nearly 80% of the people who live and work in the facility have received at least one of the shots in the two-shot series.

02.02.2021 - 22:36 [ Tagesschau.de ]

Wer mit Impfstoffen Geld verdient

Aufhorchen ließ in diesem Zusammenhang die Zusage des britisch-schwedischen Pharmakonzerns AstraZeneca, seinen Corona-Impfstoff zum „Selbstkostenpreis“ abzugeben, damit also keinen Gewinn machen zu wollen. Allerdings ist dieses Versprechen offenbar zeitlich begrenzt. Wie die „Financial Times“ unter Berufung auf ein internes Dokument berichtete, verfällt dieses Angebot im Juli. Ein kleiner, aber wichtiger Zusatz der Aussage von Konzernchef Pascal Soriot hatte darauf hingedeutet, dass der Selbstkostenpreis nur gelte, „solange die Pandemie andauert“.

27.01.2021 - 14:28 [ Zeit.de ]

Die beste Werbung für den Brexit

Die britische Regierung hatte sich mit dem Konzern im Alleingang bereits im Mai 2020 auf die Produktion und Lieferung des Impfstoffes geeinigt. Einen Monat später gab es zwar eine vorläufige Absprache von AstraZeneca mit Deutschland, Frankreich, den Niederlanden und Italien. Doch der im Juni von diesen Ländern ausgehandelte Vertrag wurde nicht abgeschlossen, sondern von der EU erst Ende August unterzeichnet. Das habe den Aufbau der Produktion der Impfdosen in Belgien entsprechend verzögert, argumentiert man bei AstraZeneca.

27.01.2021 - 14:03 [ DailyMail.co.uk ]

German media savages the EU for its vaccine shambles and tears into Ursula von der Leyen’s UK jabs threat – while jealously admiring ‚Brexit Brits‘ for ordering vaccines THREE MONTHS before Brussels

Embarrassingly for the bloc, it appears that Germany, the Netherlands, France and Italy had originally been looking to do a deal with AstraZeneca in May alongside the UK – but were blocked by the EU, which insisted it take over negotiations.

According to ITV’s Robert Peston: ‚The extra talks with the European Commission led to no material changes to the contract, but wasted time on making arrangements to make the vaccine with partner sites.‘

27.01.2021 - 02:34 [ theDispatch.com/ ]

Is the U.S. Holdup of the Oxford/AstraZeneca Vaccine Justified?

The Oxford/AstraZeneca vaccine has advantages that make it an attractive possibility. It can be stored at normal refrigeration temperatures, and its price is low relative to its competitors. Public health experts have long targeted it as ideal for use in lower and moderate-income countries because of these features.

The problem is that its U.S. Phase III trial was delayed because of an adverse event investigation in the fall, and the data from the international trials used by the U.K. government are difficult to interpret due to unplanned modifications to dosing levels.

27.01.2021 - 02:19 [ ORF.at ]

USA bestellen 200 Mio. zusätzliche Impfdosen

Wie ein US-Regierungsvertreter gestern sagte, sollen 100 Millionen Dosen des Biontech-Pfizer-Impfstoffes und 100 Millionen Dosen des US-Pharmaunternehmens Moderna bestellt werden.

27.01.2021 - 02:18 [ NBC News ]

Biden administration orders 200 million more doses of Covid-19 vaccines

The government is seeking 100 million doses from Pfizer/BioNTech and 100 million from Moderna, an order that would be made available over the summer. They would be in addition to the 400 million combined doses the companies had already committed to provide the U.S., Biden said. He said he expects to be able to confirm the purchase soon.

20.01.2021 - 12:15 [ BioProcessintl.com ]

AstraZeneca: ‘Manufacturing should take lion’s share of credit for vaccine success’

Back in March, Oxford University had “a limited manufacturing and supply capacity so they needed a partner,” Srinivasan said. “We decided to immediately offer our capacity in terms of the global reach. But that was only the beginning. Then we had to establish various alliances whether public partnerships that have been governments, or with for profit organizations or CMOs [some of which can be found here, here, and here], or not for profit organizations such as The Gates Alliance, GAVI, CEPI, and other organizations.”

06.01.2021 - 20:03 [ ZDF ]

EU lässt Moderna-Impfstoff zu

Am Mittag hatte die Europäische Arzneimittelbehörde EMA die Zulassung des Corona-Impfstoffs des US-Herstellers Moderna empfohlen. Nun hat ihn die EU-Kommission zugelassen.

27.12.2020 - 19:51 [ Forbes ]

What Every Vaccine Skeptic Should Know About The New Coronavirus Vaccines

What hasn’t been demonstrated, at least so far, is that these vaccines prevent you from getting infected entirely. We’ve shown that these vaccines provide neutralizing immunity, where the virus will no longer severely harm you, but not necessarily sterilizing immunity, where you cannot pass the virus onto others. Additionally, it isn’t known how long your immunity will persist. This, very importantly, means that you still need to wear a mask, wash/sanitize your hands, and practice social distancing — and to be rigorous about doing them all — for now.

27.12.2020 - 04:30 [ ChildrensHealthDefense.org ]

5 Questions Fauci and FDA Need to Answer on Pfizer and Moderna COVID Vaccines

1. Why didn’t the FDA’s Center for Biological Evaluation and Research require Moderna and Pfizer-BioNTech to conduct immunogenicity testing on their COVID-19 vaccines for anti-drug antibodies as recommended in the agencies’ own guidelines for drug development during clinical trials?

(…)

2. Why does the FDA seem surprised by the recent reports of life-threatening anaphylactic reactions after the agency approved emergency use of two mRNA COVID-19 vaccines that contain polyethylene glycol?

(…)

3. Why did FDA officials not acknowledge the valid and scientifically supported concerns regarding the use of PEG in COVID-19 vaccines when CHD first notified them in September?

(…)

4. Why did the FDA abandon its regulatory authority to the pharmaceutical companies developing COVID-19 vaccines?

(…)

5. Will FDA and NIAID now require mRNA vaccine manufacturers to conduct assessments of the immunogenicity of the pegylated lipid nanoparticles used in their COVID-19 vaccines, and will they also consider pre-screening of all mRNA vaccine recipients for the presence and titers of anti-PEG antibodies?

12.12.2020 - 19:43 [ New York Times ]

Blunders Eroded U.S. Confidence in Early Vaccine Front-Runner

AstraZeneca was in part to blame for the delay, said the people with knowledge of the F.D.A. talks. The company was slow to provide the F.D.A. with all the data that regulators wanted to review before allowing the trial to start up again.

In late October, after 47 days, the F.D.A. cleared the U.S. trial to restart.

It was now even further behind the late-stage trials that Pfizer and Moderna had begun in the United States about a month before AstraZeneca’s trial started.

12.12.2020 - 19:40 [ New York Times ]

Covid-19: F.D.A. Clears Pfizer Vaccine and Millions of Doses Will Be Shipped Right Away

The authorization is a historic turning point in a pandemic that has taken more than 290,000 lives in the United States. With the decision, the United States becomes the sixth country — in addition to Britain, Bahrain, Canada, Saudi Arabia and Mexico — to clear the vaccine. Other authorizations, including by the European Union, are expected within weeks.

09.12.2020 - 20:31 [ Standard.co.uk ]

How does Oxford University’s coronavirus vaccine work and how is it different to Pfizer and Moderna’s?

Does it differ to PFizer and Moderna’s vaccines?

Yes. The jabs from Pfizer and Moderna are messenger RNA (mRNA) vaccines.

Conventional vaccines are produced using weakened forms of the virus, but mRNAs use only the virus’s genetic code.

02.12.2020 - 15:25 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

(23.11.2020)

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

01.12.2020 - 11:55 [ ORF ]

Biontech, Pfizer und Moderna beantragten EU-Impfstoffzulassung

Die EMA muss die Anträge nun prüfen. Wie lange das dauert, ist unklar. Sollte die Behörde eine bedingte Zulassung empfehlen, könnte der Impfstoff noch im Dezember eingesetzt werden, teilte Biontech mit. Die endgültige Entscheidung trifft die EU-Kommission, die in der Regel der EMA-Empfehlung folgt.

23.11.2020 - 17:11 [ Politico.com ]

AstraZeneca to seek FDA authorization for vaccine based on foreign trial data

The company halted its U.S. trial in early September over safety concerns, after a trial participant reported neurological problems. The study resumed earlier this month after FDA concluded that no evidence linked the volunteer’s symptoms to the shot.

23.11.2020 - 17:04 [ Telegraph.co.uk ]

AstraZeneca shares slip after analyst says vaccine will struggle to get green light in US – live updates

SVB Leerink analyst Geoffrey Porges said the treatment may never gain approval from US regulator the FDA, and said Astra had highlighted results from a “relatively small” number of patients.

23.11.2020 - 16:40 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

23.11.2020 - 16:31 [ ORF ]

Wie Impfstoffzulassung in EU funktioniert

„Unser Plan ist es, die Impfstoffe innerhalb von 24 Stunden nach Zulassung an die Impfzentren zu liefern“, sagte Slaoui in einem Interview mit CNN. Er rechne daher damit, dass bereits am 11. oder 12. Dezember mit den Impfungen begonnen werden könne. Voraussetzung ist eine Notfallzulassung des Impfstoffs.

23.11.2020 - 16:23 [ Tagesschau.de ]

Studienergebnisse von AstraZeneca: Britischer Impfstoff wirkt zu 70 Prozent

Das Ergebnis bleibt zwar hinter den Werten der Präparate von Pfizer/Biontech und Moderna zurück. Wenn man aber zunächst nur eine halbe Dosis verabreiche und erst einen Monat später eine volle, dann erreiche der Impfstoff eine Effektivität von 90 Prozent, lässt AstraZeneca wissen. Er soll zudem deutlich preiswerter sein, sich sehr viel leichter lagern und weltweit transportieren lassen als andere Vakzine.

10.11.2020 - 17:51 [ Boris Johnson, Prime Minister of the United Kingdom / Twitter ]

Huge thanks to Kate Bingham and the Vaccine Taskforce for all their fantastic work in securing 40 million doses of the @pfizer & @BioNTech_Group vaccine and over 300 million doses of other promising vaccine candidates.

10.11.2020 - 17:36 [ Keir Shiels / Twitter ]

This vaccine needs to be kept at below -80 ^C because it uses mRNA. Not suitable for most clinics and GP practices. My money is still on Oxford to produce a more effective and ergonomic one.

10.11.2020 - 17:25 [ Tagesschau.de ]

Enges Rennen um den Impfstoff

Damit haben Biontech/Pfizer im Rennen um einen durchschlagenden Impferfolg die Nase vorn. Verbunden damit ist auch ein Durchbruch für die spezielle Technologie, die die beiden Partner, aber auch der deutsche Mitbewerber Curevac und der US-Konzern Moderna nutzen: Bei der Impfung auf mRNA-Basis „mit Erbgutschnipseln“ werden Baupläne für Proteine in die menschlichen Zellen eingeschleust, die dann Antigene herstellen – in diesem Fall gegen das Corona-Virus.

02.09.2020 - 13:12 [ Times of India ]

In change of tack, EU leaves door open to COVID vaccines purchase through WHO

The move could allow EU governments to secure vaccines from companies that are not negotiating with Brussels, such as U.S. firms Merck, Inovio and Novavax. They are all in talks with the WHO scheme, dubbed COVAX, but have so far not been reported to be involved in negotiations with the EU Commission.

11.07.2020 - 18:33 [ theGrayzone.com ]

Why the Bill Gates global health empire promises more empire and less public health

Behind a veil of corporate media PR, the Gates Foundation has served as a vehicle for Western capital while exploiting the Global South as a human laboratory. The coronavirus pandemic is likely to intensify this disturbing agenda.

25.06.2020 - 19:23 [ Politico.com ]

House members, Senate aides traded stocks in early days of coronavirus

(31.03.2020)

Holmes traded out two stocks a week later, on Jan. 29, then on Feb. 27 made two purchases that could prove advantageous in the weeks ahead: Holmes purchased between $15,001 and $50,000 of stock in each of two more companies, the pharmaceutical company Gilead, Inc. — which makes remdesivir, a drug that is currently being tested to treat coronavirus — and wipe manufacturer Clorox.

16.03.2020 - 15:10 [ labiotech.eu ]

Battle of the Biotech Unicorns: CureVac vs. Moderna

(06.11.2017)

But despite being competitors, the companies’ CEOs seem to have quite a good relationship and consider each other collaborators rather than enemies. Every year, they organize an mRNA conference together that takes turns between Boston and Berlin to bring together all the stakeholders in the field. It was at this year’s edition, in Berlin, that I had the chance to bring them together for an interview regarding the future of mRNA therapies.

16.03.2020 - 14:55 [ Fox News ]

Coronavirus: Biotech company ships first batches of vaccine, to be tested on humans: report

The trials will be held at Kaiser Permanente Washington Health Research Institute in Seattle. Testing will involve 45 young, healthy volunteers and it uses Moderna’s mRNA-1273 vaccine.

„Unlike a normal vaccine, RNA vaccines work by introducing an mRNA sequence (the molecule which tells cells what to build) which is coded for a disease-specific antigen, once produced within the body, the antigen is recognized by the immune system, preparing it to fight the real thing,“ according to the University of Cambridge.

16.03.2020 - 10:19 [ Wikipedia ]

Coalition for Epidemic Preparedness Innovations: SARS-CoV-2

In January 2020, CEPI funded three teams working on a vaccine for SARS-CoV-2, being: Moderna, Inovio Pharmaceuticals, and the University of Queensland (UQ).[28][29] By February 2020, Inovio announced that it had produced a pre-clinical DNA-based vaccination to fight COVID-19 at its lab in San Diego.[30] Inovio collaborated with a Chinese firm to speed its acceptance by regulatory authorities in China for human trialing.[31] The strategy of the UQ team is to develop a molecular clamp vaccine that genetically modifies viral proteins to make them mimic the coronavirus and stimulate an immune reaction.[29][28]

In January 2020, CEPI announced a fourth SARS-CoV-2 project in a collaboration with their existing partner CureVac, to develop and manufacture a vaccine.

16.03.2020 - 10:15 [ Marketscreener.com ]

Moderna : Germany tries to halt U.S. interest in firm working on coronavirus vaccine

CureVac in 2015 and 2018 secured financial backing for development projects from its investor the Bill & Melinda Gates Foundation, working on shots to prevent malaria and influenza.

In the field of so-called mRNA therapeutics, CureVac competes with U.S. biotech firm Moderna and German rival BioNTech, which Pfizer has identified as a potential collaboration partner.

16.03.2020 - 07:31 [ The Hill ]

Potential coronavirus vaccine trial set to start on Monday: AP

According to the AP, the trial will start testing 45 young, healthy participants with different doses of the vaccine, which was developed by both the NIH and Moderna Inc.

15.03.2020 - 20:50 [ Event201.com ]

Timetable For A Vaccine Against The New Coronavirus? Maybe This Fall: NPR

(12.02.2020)

CEPI is a global partnership of public, private and philanthropic organizations; it’s also supporting efforts at the biotech companies Moderna and CureVac.

(…)

Even in the rosiest of scenarios, Hatchett says, once the vaccine is in hand, it still needs to get to the people who need it, and that takes time — at least weeks to months, depending on the urgency.