Archiv: genes / genetic engineering / DNA / pharma / biotechnology / biomechanics / industries


26.02.2021 - 03:40 [ ec.europa.eu ]

ROADMAP FOR THE IMPLEMENTATION OF ACTIONS BY THE EUROPEAN COMMISSION BASED ON THE COMMISSION COMMUNICATION AND THE COUNCIL RECOMMENDATION ON STRENGTHENING COOPERATION AGAINST VACCINE PREVENTABLE DISEASES

(March 2019)

Examine the feasibility of developing a common vaccination card/passport for EU citizens (that takes into account potentially different national vaccination schedules and), that is compatible with electronic immunisation information systems and recognised for use across borders, without duplicating work at national level.

25.02.2021 - 08:07 [ New York Times ]

As Israel Reopens, ‘Whoever Does Not Get Vaccinated Will Be Left Behind’

(18.02.2021)

New government and business initiatives are moving in the direction of a two-tier system for the vaccinated and unvaccinated, raising legal, moral and ethical questions.

23.02.2021 - 11:19 [ Reuters ]

Israeli studies find Pfizer COVID-19 vaccine reduces transmission

(19.02.2021)

Findings of the pre-published study, not yet peer-reviewed, but based on a national database that is one of the world’s most advanced, were first reported by the Israeli news site Ynet late on Thursday and were obtained by Reuters on Friday.

Pfizer declined to comment and the Israeli Health Ministry did not respond to a request for comment.

23.02.2021 - 11:15 [ theGuardian.com ]

Covid: vaccinated Israelis to enjoy bars and hotels with ‘green pass’

(19.02.2021)

Israel is preparing itself to be split in half from next week, with the government creating a new privileged tier in society: the vaccinated.

16.02.2021 - 09:39 [ Peter Ben Embarek / Twitter ]

Thanks @kakape for the opportunity to clarify our findings. One of the misunderstanding has been about the nature of our work in the past month. It was a joint @WHO – #China mission to review the July agreed phase 1 studies and plan a series of new studies. Work in progress.

16.02.2021 - 09:37 [ Peter Daszak / Twitter ]

This was NOT my experience on @WHO mission. As lead of animal/environment working group I found trust & openness w/ my China counterparts. We DID get access to critical new data throughout. We DID increase our understanding of likely spillover pathways.

(13.02.2021)

09.02.2021 - 20:57 [ theGuardian.com ]

How can Covid vaccines be tweaked to tackle new variants?

Production BioNTech has said it can produce a fresh vaccine within six weeks of a decision being made. But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce

09.02.2021 - 12:00 [ World Health Organization (WHO) / Twitter ]

LIVE from Wuhan : Media briefing on #COVID19 origin mission

08.02.2021 - 16:35 [ Telegraph.co.uk ]

Did the Covid-19 virus really escape from a Wuhan lab?

Chan and her colleague Dr Shing Hei Zhan scrutinised the evolutions of SARS-CoV-1 (the cause of the 2003 SARS epidemic) and SARS-CoV-2 (the cause of the current pandemic) in the early months of their respective outbreaks and found that while the former mutated rapidly in early human cases, as the virus adapted to its new host, the latter did not. This implies that the virus causing Covid-19 was already well adapted to infecting human beings, a point that was also suggested by the World Health Organization in its global study on the origins of Covid-19, published in November.

There are three possible explanations for this. The first is that the virus had circulated, undetected, in people for months. The second is that the virus was already highly adept at human-to-human transmission, even while it was still in bats or other animals. The third is that it had become adapted in human cells, or humanised animals, in a laboratory.

08.02.2021 - 16:34 [ Reuters ]

New COVID-19 variant defeats plasma treatment, may reduce vaccine efficacy

(20.01.2021)

“This lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies,” the team of scientists from three South African universities working with the National Institute for Communicable Diseases (NICD) wrote in a paper in bioRxiv, a website that publishes scientific research prior to its being peer-reviewed and submitted to journals.

08.02.2021 - 16:20 [ Telegraph.co.uk ]

Exclusive: Alarming new evidence on coronavirus mutation could bring tougher restrictions

(18.12.2020)

Government scientists at the Porton Down laboratory in Wiltshire have been conducting experiments on the new strain, and have confirmed ministers‘ fears about it being far more infectious than the original strain of the virus.

08.02.2021 - 16:16 [ DailyMaverick.co.za ]

South Africa switches to J&J’s ‘silver bullet’ as AstraZeneca vaccine falters against local variant of coronavirus

“Unfortunately, viruses mutate. Sometimes this is by accident. But often the reason is that the virus wants to become more adept to infect the host.”

This, Madhi explained, was what had happened with the South African variant as well as another variant that was first identified in the United Kingdom.

08.02.2021 - 16:14 [ New York Times ]

The Coronavirus Is a Master of Mixing Its Genome, Worrying Scientists

(05.02.2021)

In recent weeks, scientists have sounded the alarm about new variants of the coronavirus that carry a handful of tiny mutations, some of which seem to make vaccines less effective.

But it is not just these small genetic changes that are raising concerns. The novel coronavirus has a propensity to mix large chunks of its genome when it makes copies of itself. Unlike small mutations, which are like typos in the sequence, a phenomenon called recombination resembles a major copy-and-paste error in which the second half of a sentence is completely overwritten with a slightly different version.

07.02.2021 - 22:52 [ ChildrensHealthDefense.org ]

501 Deaths + 10,748 Other Injuries Reported Following COVID Vaccine, Latest CDC Data Show

As of Jan. 29, about 35 million people in the U.S. had received one or both doses of a COVID vaccine. So far, only the Pfizer and Moderna vaccines have been granted Emergency Use Authorization in the U.S. by the U.S. Food and Drug Administration (FDA). By the FDA’s own definition, the vaccines are still considered experimental until fully licensed.

According to the latest data, 453 of the 501 reported deaths were in the U.S. Fifty-three percent of those who died were male, 43% were female, the remaining death reports did not include the gender of the deceased. The average age of those who died was 77, the youngest reported death was of a 23-year-old. The Pfizer vaccine was taken by 59% of those who died, while the Moderna vaccine was taken by 41%.

07.02.2021 - 22:50 [ Wavy.com ]

Virginia’s medical examiner investigating if Gloucester woman’s death was related to Pfizer COVID-19 vaccine

(05.02.2021)

A statement released Friday from State Health Commissioner M. Norman Oliver confirmed the death occurred within hours of the woman receiving the vaccine, although it did not state the day of her death.

07.02.2021 - 22:48 [ Metro.co.uk ]

X-ray worker who was ‘so excited’ to get Covid vaccine dies days after ‘severe reaction’

(27.01.2021)

‘Never been so excited to get a shot before. I am now fully vaccinated after receiving my 2nd Pfizer dose’ on Facebook on January 5. The 60 year-old uploaded a photo of his arm with a Band-Aid on it, as well as a snap of his vaccination card. But just hours later Zook suffered an upset stomach at work, and began struggling to breathe.

07.02.2021 - 22:46 [ DailyMail.co.uk ]

Californian dies hours after receiving COVID vaccine as investigation into cause of death gets underway

(24.01.2021)

– They had tested positive for COVID-19 in late December, but died hours after receiving a dose of the vaccine, local officials said
– It’s unclear if the person was given the Moderna or Pfizer vaccine
– Police say the person’s death is being investigated with an autopsy due Monday
– Dr. Dean Blumberg, an infectious disease expert at UC Davis Children’s hospital, said he believes the person’s death is ‚probably not related to the vaccine‘

07.02.2021 - 22:44 [ connexionfrance.com ]

Covid France: Five deaths after vaccine, no link proven

(20.01.2021)

The deaths were all among elderly care home residents aged 75 and over with pre-existing conditions. France’s health minister has said studies will be carried out to determine if there is a link to the vaccine or it is just ‚bad timing‘

07.02.2021 - 22:42 [ business-standard.com ]

German specialists probing 10 deaths of people vaccinated against Covid-19

(15.01.2021)

According to the medical expert, the deceased were aged from 79 to 93, all with antecedent diseases. The time between vaccination and death ranged from several hours to four days.

07.02.2021 - 22:40 [ wbrz.com ]

Virginia woman experiences anaphylaxis, dies within hours of receiving Pfizer vaccine

(04.01.2021)

According to WTKR, Drene Keyes, a gifted singer and grandmother of six, was vaccinated with the first dose of the Pfizer vaccine in the town of Warsaw shortly before she found herself unable to breathe as she began vomiting. It was after this that fluid filled her lungs and she died.

Keyes suffered from obesity, diabetes, and sleep apnea, but was still eligible for the vaccine.

07.02.2021 - 22:28 [ Massachusetts Institute of Technology (MIT) ]

So you got the vaccine. Can you still infect people? Pfizer is trying to find out.

(02.02.2021)

Whether or not the vaccines stop “onward transmission” of the virus is likely to be a critical variable in determining how the pandemic plays out and how soon life goes back to normal. Right now, researchers say, their best guess is that vaccines will reduce transmission but may not prevent it entirely.

07.02.2021 - 21:21 [ Times of Israel ]

TV: Several vaccinated elderly tested positive for COVID, but had no symptoms

Pfizer and Moderna, which produce the vaccines used in Israel, have said their shots appear to be slightly less effective in preventing the so-called South African strain of the virus, though the companies say they remain quite potent.

07.02.2021 - 21:15 [ KTOO.org ]

Juneau nursing home outbreak could be a model for what COVID-19 looks like after vaccine

(07.02.2021)

Staff and outside experts attribute the health of these people in the face of their COVID-19 infections primarily to the Pfizer and Moderna vaccines. Nearly 80% of the people who live and work in the facility have received at least one of the shots in the two-shot series.

07.02.2021 - 16:01 [ Dr. Simon, PhD in Biotech / Twitter ]

The statements that German virologist @BrinkmannLab makes are an utter disgrace. She said that a delay in measured in November 2020 cost 30,000 lives in Germany and that the same will happen again with the new „mutants“. Isn’t there any lawyer out there to legally stop her?

07.02.2021 - 15:44 [ Groo The Wonderer / Twitter ]

The left has become very authoritarian; the idea that the govt shouldn’t shut down businesses or tell people when they can leave their homes is now “ libertarian”

07.02.2021 - 15:30 [ theSun.co.uk ]

LOCKED IN: Restrictions can’t ease until NEXT YEAR due to aggressive mutant Covid strains, warns Sage

They came to their conclusions by modelling what could happen in the next few months under the vaccine rollout, presenting their findings to Sage on January 14.

Researchers at Warwick University wrote in the document, published today: “With the new aggressive covid strain, likely transmission efficacies prove insufficient to prevent further infection outbreaks across the population.

07.02.2021 - 14:54 [ Telegraph.co.uk ]

Coronavirus latest news: Restrictions on large gatherings likely to be in place ‚for next few years‘

Prof Spector also suggested that basic infection control measures – including physical distancing, face masks and handwashing – should remain in place as they „don’t cost really anything to do“.

„I think we need to get used to that and that will allow us to do the things we really want to do more easily and more readily,“ he said.

05.02.2021 - 21:32 [ Clarity / Twitter ]

The flu abruptly disappeared in March of 2020. It disappeared at about the exact same time covid-19 testing and detection ramped up. See the timing overlay below

05.02.2021 - 12:27 [ theGuardian.com ]

Ursula von der Leyen: UK is Covid vaccine ’speedboat‘ compared with EU ‚tanker‘

“I am aware that alone a country can be a speedboat, while the EU is more like a tanker,” Von der Leyen said. “Before concluding a contract with a pharmaceutical company, the 27 member states had five full days to say whether they agreed or not.

“This naturally delays the process. Indeed, we must constantly put pressure on ourselves so that each step of the decision-making process is as fast and efficient as possible.

“But I am absolutely convinced that the European approach is the right one. On these vaccines, we worked faster than usual.

02.02.2021 - 08:02 [ BusinessInsider.com ]

Elon Musk says Neuralink implanted a chip in a monkey’s brain, and now he ‚can play video games using his mind‘

Neuralink has been testing neural interfaces on animals for years. In a video released last year, Neuralink demonstrated its work on a pig named Gertrude.

02.02.2021 - 08:00 [ BusinessInsider.com ]

Elon Musk says there’s a chance his AI-brain-chip company will be putting implants in humans within a year

(May 7, 2020)

Elon Musk says the brain implant his company Neuralink is working on could potentially be ready to be put inside a patient within a year.
Musk made similar claims in 2019, saying that he hoped to have an implant in a patient by the end of 2020.

01.02.2021 - 21:30 [ Independent.co.uk ]

Elon Musk says he has ‘totally happy’ monkey with brain chip so it can play video games using its mind

Elon Musk has revealed that his Neuralink startup has implanted a wireless chip into a monkey’s brain in order to allow it to play video games.

The technology billionaire, who also heads SpaceX and Tesla, said the monkey “looks totally happy” and that Neuralink’s facilities meet US regulatory requirements.

01.02.2021 - 21:24 [ COVID-19 Genomics UK Consortium ]

COVID-19 Genomics UK Consortium

The current COVID-19 pandemic, caused by the SARS-CoV-2 virus, represents a major threat to health. The COVID-19 Genomics UK (COG-UK) consortium has been created to deliver large-scale and rapid whole-genome virus sequencing to local NHS centres and the UK government.

COG-UK is made up of an innovative partnership of NHS organisations, the four Public Health Agencies of the UK, the Wellcome Sanger Institute and over twelve academic partners providing sequencing and analysis capacity.

01.02.2021 - 21:17 [ Regierung des Vereinigten Königreichs - Gov.uk ]

Genome UK: the future of healthcare

(26 September 2020)

Genome UK sets out how the genomics community will work together to harness the latest advances in genetic and genomic science, research, and technology for the benefit of patients.

Our vision is to create the most advanced genomic healthcare ecosystem in the world, where government, the NHS, research and technology communities work together to embed the latest advances in patient care.

Our goal is that patients in the UK will benefit from world-first advances in genomic healthcare through globally leading collaborations between the government, NHS and researchers, building on already successful programmes such as the 100,000 Genomes Project, delivered by NHS England and Genomics England, and UK Biobank.

01.02.2021 - 20:30 [ Washington Post ]

Why Vaccines Might Not Be Able to Eliminate Covid-19

There’s good evidence that the shots made by Pfizer Inc.-BioNTech SE and Moderna Inc. are very effective — as much as 95% — at preventing recipients from developing Covid-19 itself. However, data haven’t been released on their ability to prevent people from developing asymptomatic infections or transmitting the virus to others. The gold standard in vaccinology is to stop infection as well as disease, providing so-called sterilizing immunity.

29.01.2021 - 05:12 [ theGuardian.com ]

Why has Germany advised against Oxford/AstraZeneca jab for over-65s?

Prof Andy Pollard, of the University of Oxford, said the lack of data is understandable. “In our trials, the older adults were recruited later and, because they were recruited later there has been less time for cases to occur, and, older adults are known to be more cautious in the pandemic, meaning the ‘attack rate’ is lower,” he said.

AstraZeneca has stressed that older adults were recruited later because the team wanted to be sure the vaccine was safe before administering it to older age groups.

28.01.2021 - 15:07 [ DailyMail.co.uk ]

Germany blocks Oxford jab for over-65s: Panel says data on older people is insufficient – but does not support ‚8% effectiveness‘ claim – amid EU row with Britain over AstraZeneca supplies

AstraZeneca’s vaccine has not been granted approval yet for general use in the European Union, but the bloc’s medicines regulator EMA is poised to authorise it on Friday.

The German panel, STIKO did not detail the data from clinical trials on the vaccine on older people, but two prominent German media outlets had reported that the efficacy on above-65s was below 10 per cent.

27.01.2021 - 19:15 [ SAfm news / Twitter ]

The EU Commission has confirmed that a meeting with the Astrazeneca pharmaceutical company will go ahead later today.

The meeting comes as a row escalates over the supply of its coronavirus vaccine. #sabcnews

27.01.2021 - 14:03 [ DailyMail.co.uk ]

German media savages the EU for its vaccine shambles and tears into Ursula von der Leyen’s UK jabs threat – while jealously admiring ‚Brexit Brits‘ for ordering vaccines THREE MONTHS before Brussels

Embarrassingly for the bloc, it appears that Germany, the Netherlands, France and Italy had originally been looking to do a deal with AstraZeneca in May alongside the UK – but were blocked by the EU, which insisted it take over negotiations.

According to ITV’s Robert Peston: ‚The extra talks with the European Commission led to no material changes to the contract, but wasted time on making arrangements to make the vaccine with partner sites.‘

27.01.2021 - 13:00 [ ABC News ]

AstraZeneca says it has not pulled out of talks with the EU on vaccine deliveries, plans meeting later Wednesday

AstraZeneca says it has not pulled out of talks with the EU on vaccine deliveries, plans meeting later Wednesday.

27.01.2021 - 12:38 [ Politico.eu ]

AstraZeneca cancels steering board meeting with EU

The cancellation follows an explosive interview with AstraZeneca CEO Pascal Soriot on Tuesday night, in which he insisted the company didn’t have a contractual obligation but rather a „best effort“ to supply the EU with its vaccine.

Instead of the meeting, the company will respond in writing to Health Commissioner Stella Kyriakides‘ demand for more information, the Commission official said. AstraZeneca did not immediately confirm this plan.

27.01.2021 - 02:34 [ theDispatch.com/ ]

Is the U.S. Holdup of the Oxford/AstraZeneca Vaccine Justified?

The Oxford/AstraZeneca vaccine has advantages that make it an attractive possibility. It can be stored at normal refrigeration temperatures, and its price is low relative to its competitors. Public health experts have long targeted it as ideal for use in lower and moderate-income countries because of these features.

The problem is that its U.S. Phase III trial was delayed because of an adverse event investigation in the fall, and the data from the international trials used by the U.K. government are difficult to interpret due to unplanned modifications to dosing levels.

26.01.2021 - 19:49 [ BBC ]

Coronavirus: Germany rejects ‚mixed up‘ reports on AstraZeneca jab

The reports emerged in Handelsblatt, a respected financial daily, and the mass-circulation Bild, quoting sources within Germany’s governing coalition.

23.01.2021 - 19:56 [ theHill.com ]

Pfizer chairman: We’re not sure if someone can transmit virus after vaccination

(DEc 3, 2020)

Pfizer chairman Albert Bourla told Dateline host Lester Holt that the pharmaceutical company was “not certain” if the vaccine prevented the coronavirus from being transmitted, saying, “This is something that needs to be examined.”

23.01.2021 - 11:00 [ Stella Kyriakides, European Commissioner for Health and Food Safety / Twitter ]

. @EU_Commission and Member States expressed deep dissatisfaction with this. We insisted on a precise delivery schedule on the basis of which Member States should be planning their vaccination programs, subject to the granting of a contitional marketing authorisation. /2

The @EU_Commission will continue to insist with @AstraZeneca on measures to increase predictability and stability of deliveries, and acceleration of the distribution of doses/3.

23.01.2021 - 10:39 [ Sky.com ]

COVID-19: AstraZeneca to ‚cut COVID-19 vaccine delivery to EU by 60%‘

The company was expected to deliver around 80 million doses to the 27 EU countries by the end of March, an EU official told the agency.

However, it now expects that to be cut to 31 million doses due to „production problems“ at a vaccine factory in Belgium run by its partner Novasep.

22.01.2021 - 18:52 [ Weltgesundheitsorganisation - WHO.int ]

Berlin, Jan 17th, 2020: Diagnostic detection of 2019-nCoV by real-time RT-PCR

All oligonucleotides were synthesised and provided by Tib-Molbiol, Berlin. Thermal cycling was performed at 55°C for 10 min for reverse transcription, followed by 95°C for 3 min and then 45 cycles of 95°C for 15 s, 58°C for 30 s.

20.01.2021 - 12:15 [ BioProcessintl.com ]

AstraZeneca: ‘Manufacturing should take lion’s share of credit for vaccine success’

Back in March, Oxford University had “a limited manufacturing and supply capacity so they needed a partner,” Srinivasan said. “We decided to immediately offer our capacity in terms of the global reach. But that was only the beginning. Then we had to establish various alliances whether public partnerships that have been governments, or with for profit organizations or CMOs [some of which can be found here, here, and here], or not for profit organizations such as The Gates Alliance, GAVI, CEPI, and other organizations.”

20.01.2021 - 11:10 [ DailyMail.co.uk ]

Slow vaccine rollout could make lockdown last PAST Easter as Priti Patel blames AstraZeneca and Pfizer for causing ’supply issues‘ by ‚upgrading their factories‘ – even though ’21m doses are already in UK‘ and Scotland is ’sitting on 400k‘

Priti Patel today blamed AstraZeneca and Pfizer for an alarming slowdown in the UK’s vaccine rollout – amid warnings the target of giving jabs to the 14million most vulnerable people by mid-February is now ‚very tight‘.

The Home Secretary pointed the finger at the firms after the daily rate fell for a third consecutive day, saying ‚upgrades‘ at factories and ‚reconfiguring‘ of supply chains were causing delays.

19.01.2021 - 17:52 [ DailyMail.co.uk ]

388 people aged under 60 with ‚NO underlying health conditions‘ have died of Covid in England’s hospitals

(27.12.2020)

Just 388 people aged under 60 with no underlying health conditions have died of Covid-19 in England’s hospitals since the start of the pandemic, NHS data has showed.

The figures show that 1,979 previously healthy people died in hospitals in England after testing positive for Covid-19 between April 2 and December 23.

19.01.2021 - 17:36 [ DerbyShireTimes.co.uk ]

Derbyshire health chiefs warn that vaccines alone will not mean an end to restrictions

“We don’t know yet whether an individual can, although not becoming ill from the virus because they have been vaccinated, still catch it and spread it on to others.

19.01.2021 - 17:24 [ Standard.co.uk ]

Vaccinated Brits told not to hug kids amid fears millions will ignore Covid rules once they have jab

Asked whether people who had received the jab could hug their children, Janet Lord, director of Birmingham University’s Institute of Inflammation and Ageing, said: “I would certainly advise not to do that at the moment because as you probably know with the vaccines they take several weeks before they are maximally effective.“

19.01.2021 - 17:20 [ bestlifeonline.com ]

The COVID Vaccine May Not Protect You From This One Thing, Experts Warn

(05.12.2020)

In order to halt the spread of coronavirus completely, a vaccine would need to produce antibodies that stop the virus from replicating. „To prevent asymptomatic infection and transmission, you need what’s called sterilizing immunity,“ Greg Poland, MD, director of the Mayo Clinic’s Vaccine Research Group, explained to USA Today. While it’s possible that one or more of the vaccines could produce sterilizing immunity, it currently remains unproven.

17.01.2021 - 17:35 [ John Crace / theGuardian.com ]

In these grim times we all need a saviour and right now it is Chris Whitty

(11.01.2021)

Cometh the hour, cometh the man. In these exceptionally grim times we’re all – Boris Johnson included – looking for a saviour to rise from these streets. And right now that salvation appears to be the England’s chief medical officer, Chris Whitty. Just about the only person left whom anyone can trust to tell the country the naked truth about coronavirus.

17.01.2021 - 17:15 [ Neil O'Brien / theGuardian.com ]

I’d love to ignore ‘Covid sceptics’ and their tall tales. But they make a splash and have no shame

They rubbished those who knew what they were talking about. Professors Chris Whitty and Patrick Vallance were “Messrs Doom and Gloom”, “fear-mongering” and “self-serving”. That Whitty and Jonathan Van-Tam used their tiny amount of spare time to volunteer in hospitals suggests that’s not true. Now, as the death toll still rises, the same people crawl from the woodwork to demand we lift all restrictions as soon as the most vulnerable are vaccinated.

17.01.2021 - 17:03 [ BMJ.com ]

Covid-19: the problems with case counting

(03 September 2020)

At the moment it seems that a polymerase chain reaction (PCR) positive result is the only criterion required for a case to be recognised.

“In any other disease we would have a clearly defined specification that would usually involve signs, symptoms, and a test result,” says Carl Heneghan, director of the Centre for Evidence Based Medicine at the University of Oxford and the editor of BMJ Evidence-Based Medicine. “We are moving into a biotech world where the norms of clinical reasoning are going out of the window. A PCR test does not equal covid-19; it should not, but in some definitions it does.”

16.01.2021 - 18:44 [ The Norwegian Medicines Agency - legemiddelverket.no ]

Covid-19 vaccination associated with adverse drug reactions in elderly people who are frail

(15.01.2021)

The reports suggest that common adverse reactions to mRNA vaccines, such as fever and nausea, may have contributed to a fatal outcome in some frail patients, says Sigurd Hortemo, chief physician at the Norwegian Medicines Agency.

The large studies on Comirnaty (BioNTec/Pfizer) did not include patients with unstable or acute illness – and included few participants over 85 years of age.

16.01.2021 - 18:33 [ Alex Berenson / Twitter ]

BIG news: Citing post-vaccination deaths, Norway now says “very frail” people should NOT receive the #Covid vaccine. Norway reports 23 post-vaccine deaths (out of only 25,000 shots). After examining 13, it says “side effects from the mRNA vaccines… may have led to deaths.”

(15.01.2021)

16.01.2021 - 13:04 [ MSN.com ]

Coronavirus D614G mutation found in 99.9% of cases at US hospital

(02.11.2020)

The finding adds credence to the theory the mutation, which accounts for 85 per cent of global cases, is more contagious than the original strain.

D614G is by far the most common strain of coronavirus affecting humans worldwide and first appeared in February in Europe.

16.01.2021 - 13:04 [ Wall Street Journal ]

The World Needs a Real Investigation Into the Origins of Covid-19

The world needs an inquiry that considers not just natural origins but the possibility that SARS-CoV-2, the virus that causes Covid-19, escaped from a laboratory. The WHO team, however, plans to build on reports by Chinese scientists rather than mount an independent investigation. Given that Chinese authorities have been slow to release information, penalized scientists and doctors who shared clinical and genomic details of the novel coronavirus, and have since demonstrated a keen interest in controlling the narrative of how the virus emerged, this is not a promising foundation for WHO’s investigation.

14.01.2021 - 09:52 [ .LancashireTelegraph.co.uk ]

Those who have received Covid jab to be offered ‚vaccine passport‘ in new trial

The news comes depsite the Vaccines Minister, Nadhim Zahawi, ruling out immunity passports back in December, a week after suggesting it was something ministers were considering, saying: “We are not looking at immunity passports at all.”

Matt Hancock also denied plans to implement passporting last week, telling the Spectator: „It’s not an area that we’re looking at.“

14.01.2021 - 09:30 [ Public Health England / Twitter ]

Even if you’ve had your #COVID19 vaccine, it’s important that you continue to follow national restrictions. We don’t yet know if the vaccine prevents transmission – you could potentially still carry and transmit the virus to other vulnerable people, even if you are protected

13.01.2021 - 18:30 [ Nature.com ]

UK science advisers: publish evidence behind COVID vaccine changes

Pfizer–BioNTech say they do not have evidence of what happens to immunity beyond 21 days after the first dose.

(…)

The JCVI adds that: “Protective immunity from the first dose likely lasts for a duration of 12 weeks.” But it has not published evidence to support this.

13.01.2021 - 18:18 [ New York Times ]

Doctor’s Death After Covid Vaccine Is Being Investigated

Shortly after receiving the vaccine, Dr. Michael developed an extremely serious form of a condition known as acute immune thrombocytopenia, which prevented his blood from clotting properly.

In a statement, Pfizer, the maker of the vaccine, said it was “actively investigating” the case, “but we don’t believe at this time that there is any direct connection to the vaccine.”

11.01.2021 - 20:39 [ University of Cambridge / Phys.org ]

Study identifies genetic changes likely to have enabled SARS-CoV-2 to jump from bats to humans

A new study, involving the University of Cambridge and led by the Pirbright Institute, has identified key genetic changes in SARS-CoV-2—the virus that causes COVID-19—that may be responsible for the jump from bats to humans, and established which animals have cellular receptors that allow the virus to enter their cells most effectively.

The genetic adaptions identified were similar to those made by SARS-CoV—which caused the 2002-2003 SARS epidemic—when it adapted from bats to infect humans.

11.01.2021 - 09:13 [ Abir Ballan, Master in Public Health| Psychology / Twitter ]

They used a tactical warfare strategy against us. ‚Divide and conquer‘. We fell for it. Now we must become aware of it and fight back. We must reunite. We must find true solidarity to save our world. To free ourselves. To regain our autonomy.

Understand the strategy of your opponent and think of your next move.

We, the people, are the only ones who know what is for our greater good. The people on top who are pulling the strings don’t know what is good for us and don’t care about what is good for us. They only care about their self-interests and what is good for them.

11.01.2021 - 07:55 [ Dr Naomi Wolf / Twitter ]

Oh. My. God. Huge new restrictions in Sweden. It’s looking a lot like a global coup based on/predicated upon medical fascism.

09.01.2021 - 18:18 [ BMJ.com ]

Covid-19: the problems with case counting

(03 September 2020)

At the moment it seems that a polymerase chain reaction (PCR) positive result is the only criterion required for a case to be recognised.

“In any other disease we would have a clearly defined specification that would usually involve signs, symptoms, and a test result,” says Carl Heneghan, director of the Centre for Evidence Based Medicine at the University of Oxford and the editor of BMJ Evidence-Based Medicine. “We are moving into a biotech world where the norms of clinical reasoning are going out of the window. A PCR test does not equal covid-19; it should not, but in some definitions it does.”

04.01.2021 - 22:34 [ Diogo Simão Lemos / Twitter ]

• @ECDC_EU assesses that the probability of #SARSCoV2 VOC 202012/01 and 501.V2 being introduced and further spread in the EU/EEA is currently 𝐡𝐢𝐠𝐡. 1/4

(29.12.2020)

(…)

Therefore, the overall risk of an increased impact on health systems in the coming weeks is assessed as 𝐡𝐢𝐠𝐡. 4/4

04.01.2021 - 22:31 [ yenisafak.com ]

ECDC releases report on new COVID-19 strain

(22 Dec 2020)

Noting that the ECDC’s report on the new strain was published last night, Balik said “this mutant variant has been named SARS-CoV-2 VUI 202012/01 [Variant Under Investigation, year 2020, month 12, variant 01] for now.”

Balik said the report points out the importance of a comprehensive examination of the new strain.

03.01.2021 - 18:22 [ theAustralian.com.au ]

Coronavirus: Scientists cast doubt on WHO’S China mission to find COVID-19 origin in Wuhan

(today)

Daszak was a frequent traveller to Wuhan and the bat colonies of Yunnan with WIV scientists on projects funded by EcoHealth with US grants — until the Trump administration abruptly severed support, citing bio-security concerns.

The British scientist has forcefully dismissed the scenario of a laboratory leak as “baloney” and a “conspiracy theory”, and praised the work of his Chinese counterparts, notably Shi Zhengli, the “bat woman” of Wuhan, who traced the origins of the earlier Sars coronavirus outbreak to a colony of horseshoe bats in Yunnan.

03.01.2021 - 18:16 [ DailyMail.co.uk ]

The world must investigate all the mounting evidence Covid leaked from a Wuhan lab, writes IAN BIRRELL

(2 January 2021 | Updated: 12:06 GMT, 3 January 2021)

Now there is growing clamour from experts around the world that no stone should be left unturned during this inquiry – and that it must include one key element of a hunt which has all the hallmarks of a thriller novel.

This centres on a cave filled with bats, a clutch of mysterious deaths, some brilliant scientists carrying out futuristic experiments in a secretive laboratory – and a cover-up of epic proportions that, if proven, would have huge consequences for the Chinese Communist Party and the global practice of science.

03.01.2021 - 18:07 [ ChildrensHealthDefense.org ]

Did Top Medical Journal Help Cover Up Origins of SARS-CoV-2?

(11.09.2020)

– According to Alina Chan, a molecular biologist at the Broad Institute of Harvard and MIT, SARS-CoV-2 did not evolve in a manner you’d expect, had it jumped from an animal to a human. It sprang into action fully evolved for human transmission
– It appears Nature, a top medical journal, has allowed authors to secretly alter data sets in their papers without publishing notices of correction
– Chan’s investigation reveals authors have renamed samples, failed to attribute them properly, and produced a genomic profile that doesn’t match the samples in their paper. Others are missing data
– RaTG13 — the coronavirus that most resembles SARS-CoV-2, being 96% identical — is actually btCoV-4991, a virus found in samples collected in 2013 and published in 2016
– If SARS-CoV-2, the virus responsible for COVID-19 and the subsequent response to it, came from a lab, then we need to reassess the future of gain-of-function research that allows for the weaponization of viruses

03.01.2021 - 17:53 [ Alina Chan / Twitter / threadreaderapp.com ]

Get ready. This is going to be an important thread. Election season will be over soon and hopefully more people will devote some attention to this… I’m going to walk through a timeline of SARS2-related virus data published in the months after the outbreak. (1/30)

(25 Oct 20)

Since the outbreak in late 2019, events have been unfolding at such a fast pace that it is difficult to keep track of what happened and in what order.

I use visualizations of the timeline to follow key events relating to the search for the animal host of SARS2. (2/30)

Even today, I still hear people saying that SARS-CoV-2 came from pangolins and a Seafood market in Wuhan. I hope this analysis will help to clear things up. It will refresh us on significant early pandemic events and major publications discussing the origins of the virus (3/30).

03.01.2021 - 17:36 [ Annette Gartland / changingtimes.media ]

SARS-CoV-2: lab-origin hypothesis gains traction

(October 12, 2020)

– Researchers say there’s evidence within the SARS-CoV-2 spike protein that suggests the virus is a product of genetic manipulation.
– Exiled Chinese scientist Li-Meng Yan says SARS-CoV-2 is an “unrestricted bioweapon” and there’s been “large-scale, organised scientific fraud”.
– Six miners in Yunnan, who were removing bat faeces from a cave, suffered a severe pneumonia-like illness in 2012 and three of them died. They had a high fever, dry cough, sore limbs, and headaches – all symptoms associated with Covid-19.
– A database containing information about the sequencing of samples collected from the Yunnan mine by researchers from the Wuhan Institute of Virology has been taken offline.
– There are said to be sequences of HIV-1 in the SARS-CoV-2 genome.
American and Chinese scientists have collaborated for decades on gain-of-function research.
– There have been numerous ‘leaks’ of viruses from laboratories, including during the SARS outbreak in 2003–2004.

03.01.2021 - 17:07 [ The Australian / ecambiomed.com ]

THE AUSTRALIAN | RaBtCoV/4991 | Out of the bat cave: China’s deadly maze Deep in China, three men entered a cave and died with a mystery illness. Why was it kept under wraps for years?

(July 6th, 2020)

Ebright believes an even more controversial theory should not be ruled out. “It also, of course, is a distinct possibility that work done in the laboratory on RaTG13 may have resulted in artificial in-laboratory adaptation that erased those three to five decades of evolutionary distance.”

It is a view Hibberd does not believe is possible. “Sars-Cov-2 and RaTG13 are not the same virus and I don’t think you can easily manipulate one into the other. It seems exceptionally difficult.”

Ebright alleges, however, that the type of work required to create COVID-19 from RaTG13 was “identical” to work the laboratory had done in the past. “The very same techniques, the very same experimental strategies using RaTG13 as the starting point, would yield a virus essentially identical to Sars-Cov-2.”

03.01.2021 - 16:55 [ Dr. Jurgen Mayer / Peakprosperity.com ]

Scientific history of RaTG13

(Jul 07, 2020)

In early February 2019, Dr. Shi’s team suddenly tossed a brand new genome online and published a paper, citing that hCoV-2019 must come from (horseshoe) Bats because it is so similar to this other sample obtained from Bats in July 2013.

*If an existing genome was already in the system and the new data was uploaded we would expect to see reference notes and that the previous listing had been removed or updated.

*The scientists were forcing an argument that this newly published genome (RaTG13) came from a Bat and is the closest relative to hCoV-2019, therefore our pandemic virus more than likely came from a bat.

At the time of this publication, there is quite literally zero record or publication referencing this sudden new virus that they designated as Bat SL-CoV RaTG13 (Ra being Rhinolophus affinis, 13 being sampling year). How could this new virus have been just ABSENT from the scientific community for SEVEN YEARS?!

In fact, there are (comparatively) barely any Rhinolophus Affinis Samples in our databases. Meaning there is a small pool or Bat viruses from this specific species. The team simply renamed the sample and maybe forgot that 4991 was already in GenBank?! Because 4991 is actually RaTG13, yet this super important publication which was read by all of the top scientists in the world makes zero mention of this important fact.

03.01.2021 - 16:33 [ Shing Hei Zhan, Benjamin E. Deverman, Yujia Alina Chan / bioRxiv.org ]

SARS-CoV-2 is well adapted for humans. What does this mean for re-emergence?

(May 02, 2020)

Abstract: In a side-by-side comparison of evolutionary dynamics between the 2019/2020 SARS-CoV-2 and the 2003 SARS-CoV, we were surprised to find that SARS-CoV-2 resembles SARS-CoV in the late phase of the 2003 epidemic after SARS-CoV had developed several advantageous adaptations for human transmission. Our observations suggest that by the time SARS-CoV-2 was first detected in late 2019, it was already pre-adapted to human transmission to an extent similar to late epidemic SARS-CoV. However, no precursors or branches of evolution stemming from a less human-adapted SARS-CoV-2-like virus have been detected. The sudden appearance of a highly infectious SARS-CoV-2 presents a major cause for concern that should motivate stronger international efforts to identify the source and prevent near future re-emergence.

03.01.2021 - 08:21 [ Sky.News ]

COVID-19: Chief medical officer Chris Whitty warns coronavirus vaccine shortages will last months

(01.01.2021)

„At the moment it doesn’t look good – a hole is appearing because there’s a lack of other approved vaccines and we have to fill the gap with our own vaccine,“ BioNTech CEO Ugur Sahin told news weekly Spiegel.

03.01.2021 - 08:08 [ Times of India ]

Global partnership COVAX secures two billion COVID-19 vaccine doses

(19.12.2020)

UNITED NATIONS: Global vaccine partnership COVAX has lined up almost two billion doses of existing and candidate COVID-19 vaccines for use worldwide, including 200 million doses of the AstraZeneca/Oxford vaccine through an agreement between the Vaccine Alliance Gavi, the Serum Institute of India and the Bill and Melinda Gates Foundation.

03.01.2021 - 06:56 [ DailyMail.co.uk ]

Boris Johnson hails Oxford vaccine as a ‚triumph for British science‘ and says he is ‚confident this is the year we will defeat coronavirus‘

The initial supplies of Oxford-AstraZeneca vaccine have been produced by a company called Halix in the Netherlands.

Once produced in bulk, the vaccine goes to a plant in Wrexham, run by an Indian company called Wockhardt, where it is decanted into vials in a process known as ‚fill and finish‘. The plant can bottle at least 150,000 doses a day.

02.01.2021 - 19:20 [ theSun.co.uk ]

First Oxford Covid vaccine doses arrive at UK hospitals with 530,000 jabs to be rolled out from Monday

While the Oxford vaccine uses a harmless, weakened version of a common virus in chimpanzees, the Pfizer jab is known as a messenger vaccine (MRNA), using a genetic code rather than a weakened form of the virus.

And experts have urged patients not to mix and match the two.

02.01.2021 - 08:17 [ Sky.News ]

COVID-19: Chief medical officer Chris Whitty warns coronavirus vaccine shortages will last months

„At the moment it doesn’t look good – a hole is appearing because there’s a lack of other approved vaccines and we have to fill the gap with our own vaccine,“ BioNTech CEO Ugur Sahin told news weekly Spiegel.

30.12.2020 - 03:58 [ mark cording / Twitter ]

What’s the update on the Oxford vaccine Mr Hancock

30.12.2020 - 03:50 [ Matt Hancock, secretary of State for Health & Social Care / Twitter ]

Fantastic to see Margaret Keenan receive her second dose of the @Pfizer /@BioNTech_Group #coronavirus vaccine

30.12.2020 - 03:38 [ BBC ]

Covid: Millions more braced for tougher rules in England

Government sources have indicated an announcement later will see more areas move into tier four – „stay at home“.

Health Secretary Matt Hancock is due to detail the changes – which could be introduced within days – in the House of Commons after 14:30 GMT.

30.12.2020 - 03:35 [ noone@nowhere / Twitter ]

Still no Oxford vaccine emergency approval. Unbelievable.

(23.12.2020)

28.12.2020 - 17:26 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

28.12.2020 - 17:25 [ Telegraph.co.uk ]

Coronavirus latest news: One million vaccinations a week will not bring pandemic under control, warns Sage expert

Sir Jeremy Farrar, the director of the Wellcome Trust who advises Number 10’s advisory panel Scientific Advisory Group for Emergencies (Sage) said: „We’re not going to be free of this pandemic by February, this is now a human endemic infection.

28.12.2020 - 17:24 [ .oxfordmail.co.uk ]

No herd immunity through vaccine programme before summer, Sage scientist warns

Calum Semple, professor of outbreak medicine at the University of Liverpool and a member of the Scientific Advisory Group for Emergencies (Sage), described the Oxford/AstraZeneca vaccine as a “game changer” if it is approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the coming days.

But he told BBC Breakfast…

28.12.2020 - 17:20 [ DailyMail.co.uk ]

SAGE demands ALL pupils are kept home till February: Scientists demand new national lockdown for kids after Gove says only Years 11 and 13 and primary schools will return on January 4

Pressure has also been growing on Boris Johnson from within his own party to keep all pupils in school at the start the new term – but the PM has sided with SAGE scientists, who are pushing for schools, especially secondary schools to close for all of January, at least, because of the new super-strain of Covid-19, according to Politico.

Mr Johnson was reportedly told last week by SAGE, led by Chief Scientific Adviser Patrick Vallance, that a stricter lockdown is required because the one in November, where schools remained open, did not keep the ‚R‘ rate below 1, an adviser has claimed.

27.12.2020 - 19:51 [ Forbes ]

What Every Vaccine Skeptic Should Know About The New Coronavirus Vaccines

What hasn’t been demonstrated, at least so far, is that these vaccines prevent you from getting infected entirely. We’ve shown that these vaccines provide neutralizing immunity, where the virus will no longer severely harm you, but not necessarily sterilizing immunity, where you cannot pass the virus onto others. Additionally, it isn’t known how long your immunity will persist. This, very importantly, means that you still need to wear a mask, wash/sanitize your hands, and practice social distancing — and to be rigorous about doing them all — for now.

27.12.2020 - 05:22 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

27.12.2020 - 05:20 [ Sean / Twitter ]

Can I ask why the Oxford vaccine approval is taking so long? It only took 23 days for Pfizers, we are nearly at day 30 and still no sign of approval!

(21.12.2020)

27.12.2020 - 05:05 [ Telegraph.co.uk ]

Millions to receive Oxford coronavirus vaccine from Jan 4

The Government is aiming for two million people to receive their first dose of either the Oxford vaccine or the Pfizer jab within a fortnight as part of a major ramping up of the inoculation programme.

27.12.2020 - 04:30 [ ChildrensHealthDefense.org ]

5 Questions Fauci and FDA Need to Answer on Pfizer and Moderna COVID Vaccines

1. Why didn’t the FDA’s Center for Biological Evaluation and Research require Moderna and Pfizer-BioNTech to conduct immunogenicity testing on their COVID-19 vaccines for anti-drug antibodies as recommended in the agencies’ own guidelines for drug development during clinical trials?

(…)

2. Why does the FDA seem surprised by the recent reports of life-threatening anaphylactic reactions after the agency approved emergency use of two mRNA COVID-19 vaccines that contain polyethylene glycol?

(…)

3. Why did FDA officials not acknowledge the valid and scientifically supported concerns regarding the use of PEG in COVID-19 vaccines when CHD first notified them in September?

(…)

4. Why did the FDA abandon its regulatory authority to the pharmaceutical companies developing COVID-19 vaccines?

(…)

5. Will FDA and NIAID now require mRNA vaccine manufacturers to conduct assessments of the immunogenicity of the pegylated lipid nanoparticles used in their COVID-19 vaccines, and will they also consider pre-screening of all mRNA vaccine recipients for the presence and titers of anti-PEG antibodies?

23.12.2020 - 11:32 [ BBC ]

Oxford vaccine: How did they make it so quickly?

(23.11.2020)

Scientists took a common cold virus that infected chimpanzees and engineered it to become the building block of a vaccine against almost anything.

Before Covid, 330 people had been given ChAdOx1 based-vaccines for diseases ranging from flu to Zika virus, and prostate cancer to the tropical disease chikungunya.

The virus from chimps is genetically modified so it cannot cause an infection in people. It can then be modified again to contain the genetic blueprints for whatever you want to train the immune system to attack.

23.12.2020 - 11:18 [ inews.co.uk ]

Boris Johnson’s future as Prime Minister rests on the Oxford vaccine being approved

The hope in Downing Street is that the Oxford vaccine will get the green light by the end of the year. This would allow the Prime Minister to start laying out plans for restrictions to be lifted.

21.12.2020 - 22:37 [ DailyMail.co.uk ]

UK has vaccinated 500,000 people against Covid since December 8, Boris Johnson says as regulators face growing pressure to approve Oxford’s jab in desperate race to speed up the roll-out

The MHRA drugs regulator has been doing its final review of the vaccine for three weeks now, since November 27, with a decision expected by next Tuesday.

(…)

However, they made a decision about Pfizer and BioNTech’s jab within 10 days of being instructed to do so by the Department of Health.

21.12.2020 - 22:35 [ New York Times ]

How the Oxford-AstraZeneca Vaccine Works

The Oxford-AstraZeneca team used a modified version of a chimpanzee adenovirus, known as ChAdOx1. It can enter cells, but it can’t replicate inside them. (…)

The Oxford-AstraZeneca vaccine for Covid-19 is more rugged than the mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. As a result, the Oxford vaccine doesn’t have to stay frozen.

21.12.2020 - 21:45 [ BJG, Former National Press Secretary for #BernieSanders2020 / Twitter ]

Why don’t elected Democrats support a bill that nearly 90% of Democratic voters support? #ForceTheVote

21.12.2020 - 21:41 [ Jacobin Magazine ]

A New Congressional Budget Office Study Shows That Medicare for All Would Save Hundreds of Billions of Dollars Annually

The most exhaustive study on Medicare for All just came out. Its conclusion: a single-payer system would guarantee health insurance to all people while reducing overall health spending by hundreds of billions of dollars every year.

21.12.2020 - 09:00 [ Wiley Online Library ]

The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin

(17.11.2020)

We here describe how the two main SARS‐CoV‐2 features, (1) the presence of a furin cleavage site missing in other CoVs of the same group and (2) an receptor binding domain (RBD) optimized to bind to human cells[2] might be the result of lab manipulation techniques such as site‐directed mutagenesis. The acquisition of both unique features by SARS‐CoV‐2 more or less simultaneously is less likely to be natural or caused only by cell/animal serial passage.

20.12.2020 - 15:24 [ DailyMail.co.uk ]

It felt like a meeting of horror movie scriptwriters: GLEN OWEN tells the inside story of how a libertarian PM ended up feeling he had no choice but to cancel Christmas

The grim countenances of Chris Whitty and Sir Patrick Vallance told the story before they even started talking – Christmas was off. As Boris Johnson sat in the Cabinet Room at 5pm on Friday, Whitty and Vallance appeared on the Zoom monitors and started reeling off increasingly alarming data about the new mutant strain of the coronavirus…

20.12.2020 - 10:00 [ theHill.com ]

FDA investigating allergic reactions to Pfizer vaccine reported in multiple states

“We are working hand in hand with the Centers for Disease Control and Prevention (CDC), and we’ve actually been working closely with our United Kingdom colleagues, who of course reported the allergic reaction. I think we’ll be looking at all the data we can from each of these reactions to sort out exactly what happened, and we’ll also be looking to try to understand which component of the vaccine might be helping to produce them,” Marks said.

19.12.2020 - 20:43 [ Downing Street No 10 / Regierung von Großbritannien ]

Prime Minister announces Tier 4: ‚Stay At Home‘ Alert Level in response to new COVID variant

The Prime Minister has announced tougher restrictions for large parts of South East England with a new Tier 4: ‘Stay at Home’ alert level.

The decision follows a rapid rise in infections attributed to the rapid spread of a new variant of COVID-19.

Based on preliminary modelling data, the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) now consider that the new strain can spread significantly more quickly and could increase R by 0.4 or more. New and existing data will continue to be analysed as we learn more about the variant.

19.12.2020 - 20:38 [ Telegraph.co.uk ]

Exclusive: Alarming new evidence on coronavirus mutation could bring tougher restrictions

Government scientists at the Porton Down laboratory in Wiltshire have been conducting experiments on the new strain, and have confirmed ministers‘ fears about it being far more infectious than the original strain of the virus.

(…)

The meeting of ministers was expected to continue late into the night, with Whitehall sources refusing to rule out a press conference on Saturday to announce additional restrictions.

17.12.2020 - 09:19 [ USA Today ]

FDA says Pfizer’s COVID-19 vaccine vials may hold extra ‚obtainable‘ doses, adding to US supply

Pharmacists must throw away any extra amount of the vaccine if it does not consist of the 0.3 mL needed for a full dose, Pfizer said. The remaining amount „must never“ be combined with the vaccine from another vial.

The Pfizer vaccine, green-lighted by the FDA on Dec. 11, was developed in less than a year, a fraction of the time it would usually take as researchers worldwide frantically sought an antidote to a virus discovered in China in December 2019.

17.12.2020 - 08:55 [ New York Times ]

2 Alaska Health Workers Got Emergency Treatment After Receiving Pfizer’s Vaccine

One of the workers, who did not have a history of allergies, remained in the hospital on Wednesday night. Some reactions to the vaccine were also reported last week in Britain.

15.12.2020 - 10:12 [ BMJ ]

Peter Doshi: Pfizer and Moderna’s “95% effective” vaccines—let’s be cautious and first see the full data

(26.11.2020)

Let’s put this in perspective. First, a relative risk reduction is being reported, not absolute risk reduction, which appears to be less than 1%. Second, these results refer to the trials’ primary endpoint of covid-19 of essentially any severity, and importantly not the vaccine’s ability to save lives, nor the ability to prevent infection, nor the efficacy in important subgroups (e.g. frail elderly). Those still remain unknown.

14.12.2020 - 23:53 [ FT.com ]

Researchers looking at new coronavirus strain, says health minister

Chris Whitty, England’s chief medical officer, told a press conference that London was being moved to more stringent Tier 3 restrictions because cases were surging in and around the capital — and not directly in response to the discovery of the new variant.

13.12.2020 - 19:40 [ BMJ.com ]

Conflicts of interest among the UK government’s covid-19 advisers

(09.12.2020)

Little is known about the interests of the doctors, scientists, and academics on whose advice the UK government relies to manage the pandemic. Attempts to discover more are frequently thwarted, finds Paul D Thacker

13.12.2020 - 14:55 [ CormanDrostenReview.com ]

Review report Corman-Drosten et al. Eurosurveillance 2020

(27.11.2020)

It should be noted that there is no mention anywhere in the Corman-Drosten paper of a test being positive or negative, or indeed what defines a positive or negative result. These types of virological diagnostic tests must be based on a SOP, including a validated and fixed number of PCR cycles (Ct value) after which a sample is deemed positive or negative. The maximum reasonably reliable Ct value is 30 cycles. Above a Ct of 35 cycles, rapidly increasing numbers of false positives must be expected .

PCR data evaluated as positive after a Ct value of 35 cycles are completely unreliable.

13.12.2020 - 14:50 [ National Center for Biotechnology Information - ncbi.nlm.nih.gov ]

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

(23.01.2020)

All oligonucleotides were synthesised and provided by Tib-Molbiol (Berlin, Germany). Thermal cycling was performed at 55 °C for 10 min for reverse transcription, followed by 95 °C for 3 min and then 45 cycles of 95 °C for 15 s, 58 °C for 30 s.

(…)

This work was funded by European Union DG Research through projects Prepare (GA602525), Compare (GA643476), and EVAg (GA653316); by European Union DG SANCO through EVD-LabNet, as well as by the German Ministry of Research through projects RAPID (01KI1723A) and DZIF (301-4-7-01.703).

13.12.2020 - 14:41 [ WHO.int ]

Berlin, Jan 17th, 2020: Diagnostic detection of 2019-nCoV by real-time RT-PCR

All oligonucleotides were synthesised and provided by Tib-Molbiol, Berlin. Thermal cycling was performed at 55°C for 10 min for reverse transcription, followed by 95°C for 3 min and then 45 cycles of 95°C for 15 s, 58°C for 30 s.

12.12.2020 - 20:00 [ CNN ]

It took AstraZeneca researchers 1 month to get vaccine trial data to FDA, source tells CNN

(14.10.2020)

The source said the root of the delay is that the participant was in the United Kingdom, and the European Medicines Agency and the FDA store data differently.

„They had to convert data from one format to another format. It’s like taking stuff off a PC and putting it onto an Apple. They had to spend a lot of hours to get what they wanted,“ the source said.

12.12.2020 - 19:43 [ New York Times ]

Blunders Eroded U.S. Confidence in Early Vaccine Front-Runner

AstraZeneca was in part to blame for the delay, said the people with knowledge of the F.D.A. talks. The company was slow to provide the F.D.A. with all the data that regulators wanted to review before allowing the trial to start up again.

In late October, after 47 days, the F.D.A. cleared the U.S. trial to restart.

It was now even further behind the late-stage trials that Pfizer and Moderna had begun in the United States about a month before AstraZeneca’s trial started.

12.12.2020 - 19:40 [ New York Times ]

Covid-19: F.D.A. Clears Pfizer Vaccine and Millions of Doses Will Be Shipped Right Away

The authorization is a historic turning point in a pandemic that has taken more than 290,000 lives in the United States. With the decision, the United States becomes the sixth country — in addition to Britain, Bahrain, Canada, Saudi Arabia and Mexico — to clear the vaccine. Other authorizations, including by the European Union, are expected within weeks.

11.12.2020 - 14:15 [ Times of Israel ]

Israel said considering restrictions on those who refuse COVID vaccine

Under the proposal being considered, those who refuse to be inoculated will only be allowed to fly, attend certain events, dine at restaurants or frequent cultural venues by providing a recent negative result from a coronavirus test, according to Channel 12 news, which quoted unnamed senior officials.

Health officials were also reportedly considering barring medical personnel who refuse vaccination from working in coronavirus wards or intensive care units.

09.12.2020 - 20:31 [ Standard.co.uk ]

How does Oxford University’s coronavirus vaccine work and how is it different to Pfizer and Moderna’s?

Does it differ to PFizer and Moderna’s vaccines?

Yes. The jabs from Pfizer and Moderna are messenger RNA (mRNA) vaccines.

Conventional vaccines are produced using weakened forms of the virus, but mRNAs use only the virus’s genetic code.

09.12.2020 - 18:18 [ Standard.co.uk ]

Warning after two NHS workers have allergic reaction to Pfizer/BioNTech Covid vaccine

They developed symptoms of “anaphylactoid reaction” shortly after receiving the vaccine, but both recovered after the appropriate treatment.

After the incident, the Medicines and Healthcare products Regulatory Agency (MHRA) told NHS trusts that anyone who has a history of “significant” allergic reactions – including to medicines, food or vaccines – should not currently receive the vaccine.

06.12.2020 - 15:48 [ Kulvinder Kaur MD, Physician / Twitter ]

There’s NO evidence that Covid candidate vaccines prevent infection, prevent/reduce transmission, reduce hosps or reduce mortality. Nor are clinical trials designed to determine these endpoints. Longterm efficacy/safety also unknowns All we know—may reduce “common cold symptoms”

06.12.2020 - 15:45 [ BMJ ]

Peter Doshi: Pfizer and Moderna’s “95% effective” vaccines—let’s be cautious and first see the full data

(26.11.2020)

Let’s put this in perspective. First, a relative risk reduction is being reported, not absolute risk reduction, which appears to be less than 1%. Second, these results refer to the trials’ primary endpoint of covid-19 of essentially any severity, and importantly not the vaccine’s ability to save lives, nor the ability to prevent infection, nor the efficacy in important subgroups (e.g. frail elderly). Those still remain unknown. Third, these results reflect a time point relatively soon after vaccination, and we know nothing about vaccine performance at 3, 6, or 12 months, so cannot compare these efficacy numbers against other vaccines like influenza vaccines (which are judged over a season). Fourth, children, adolescents, and immunocompromised individuals were largely excluded from the trials, so we still lack any data on these important populations.

I previously argued that the trials are studying the wrong endpoint, and for an urgent need to correct course and study more important endpoints like prevention of severe disease and transmission in high risk people. Yet, despite the existence of regulatory mechanisms for ensuring vaccine access while keeping the authorization bar high (which would allow placebo-controlled trials to continue long enough to answer the important question), it’s hard to avoid the impression that sponsors are claiming victory and wrapping up their trials (Pfizer has already sent trial participants a letter discussing “crossing over” from placebo to vaccine), and the FDA will now be under enormous pressure to rapidly authorize the vaccines.

04.12.2020 - 21:50 [ CNN ]

Vaccination cards will be issued to everyone getting Covid-19 vaccine, health officials say

(02.12.2020)

„Everyone will be issued a written card that they can put in their wallet that will tell them what they had and when their next dose is due,“ Moore said. „Let’s do the simple, easy thing first. Everyone’s going to get that.“

04.12.2020 - 21:47 [ Zero Hedge ]

‚Immunity Cards‘ To Be Issued To All Americans; Enable CDC To Track COVID-19 Vaxx Status In Database

On Wednesday the Department of Defense released the first images of a COVID-19 vaccination record card as well as vaccination kits, according to CNN.

„Everyone will be issued a written card that they can put in their wallet that will tell them what they had and when their next dose is due,“ says Dr. Kelly Moore, associate director of the Immunization Action Coalition.

04.12.2020 - 21:33 [ theLocal.ch ]

‚Freedom Pass‘: Will Switzerland introduce a British-style coronavirus immunity card?

Ruth Humbel, a National Councillor with the Swiss People’s Party, said that people who are immune to the virus should receive a card or certificate which will allow them to participate in certain activities, such as going to football games, clubs or travelling, 20 Minutes reports.

04.12.2020 - 21:24 [ DailyMail.co.uk ]

No10 stops short of ruling out Covid ‚immunity passports‘ despite saying it is ’not something the PM wants‘ – as Wales raises fears of spot checks at pubs and shops by bringing in ID-style cards for people who get vaccine

– Pfizer vaccines licensed by UK regulator and will be distributed from next week
– Wales says people will be issued with ID-style cards to show they have had jab
– Fears that pubs and shops could demand proof of vaccine before allowing entry

04.12.2020 - 20:50 [ InfectiousDiseaseAdvisor.com ]

Challenges in Assessing the Efficacy of COVID-19 Vaccines

Determining whether a vaccine can protect against severe disease and death from COVID-19 may not be possible in phase 3 clinical trials and will often require long-term, ongoing studies after widespread deployment of a vaccine.

To ensure ongoing evaluation of vaccine safety, well-supported pharmacovigilance studies after licensure will be necessary.

04.12.2020 - 20:47 [ theHill.com ]

Pfizer chairman: We’re not sure if someone can transmit virus after vaccination

Pfizer chairman Albert Bourla told Dateline host Lester Holt that the pharmaceutical company was “not certain” if the vaccine prevented the coronavirus from being transmitted, saying, “This is something that needs to be examined.”

03.12.2020 - 19:54 [ DailyMail.co.uk ]

Why is the Pfizer vaccine so difficult to transport? Light, temperatures above -70C and movement ALL speed up the chemical reactions that destroy fragile mRNA — meaning care homes have been sidelined

The approval of Pfizer/BioNTech’s coronavirus vaccine on Wednesday was hailed as the light at the end of the lockdown tunnel that could finally revert Britain back to pre-pandemic normality.

But the breakthrough jab — shown to be 95 per cent effective at blocking Covid-19 infection — has thrown up a series of logistical hurdles that make getting the vaccine to those who need it most challenging, including care homes.

02.12.2020 - 16:10 [ Wiley Online Library ]

The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin

(17.11.2020)

We here describe how the two main SARS‐CoV‐2 features, (1) the presence of a furin cleavage site missing in other CoVs of the same group and (2) an receptor binding domain (RBD) optimized to bind to human cells[2] might be the result of lab manipulation techniques such as site‐directed mutagenesis. The acquisition of both unique features by SARS‐CoV‐2 more or less simultaneously is less likely to be natural or caused only by cell/animal serial passage.

02.12.2020 - 15:25 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

(23.11.2020)

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

02.12.2020 - 15:19 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

02.12.2020 - 15:13 [ apnrews.com ]

UK authorizes Pfizer coronavirus vaccine for emergency use

The Medicines and Healthcare Products Regulatory Agency, which licenses drugs in the U.K., recommended the vaccine could be used after it reviewed the results of clinical trials that showed the vaccine was 95% effective overall — and that it also offered significant protection for older people, among those most at risk of dying from the disease.

23.11.2020 - 17:11 [ Politico.com ]

AstraZeneca to seek FDA authorization for vaccine based on foreign trial data

The company halted its U.S. trial in early September over safety concerns, after a trial participant reported neurological problems. The study resumed earlier this month after FDA concluded that no evidence linked the volunteer’s symptoms to the shot.

23.11.2020 - 17:04 [ Telegraph.co.uk ]

AstraZeneca shares slip after analyst says vaccine will struggle to get green light in US – live updates

SVB Leerink analyst Geoffrey Porges said the treatment may never gain approval from US regulator the FDA, and said Astra had highlighted results from a “relatively small” number of patients.

23.11.2020 - 16:40 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

14.11.2020 - 15:59 [ BMJ.com ]

Covid-19: politicisation, “corruption,” and suppression of science

Science is being suppressed for political and financial gain. Covid-19 has unleashed state corruption on a grand scale, and it is harmful to public health.1 Politicians and industry are responsible for this opportunistic embezzlement. So too are scientists and health experts. The pandemic has revealed how the medical-political complex can be manipulated in an emergency—a time when it is even more important to safeguard science.

The UK’s pandemic response provides at least four examples of suppression of science or scientists. First, the membership, research, and deliberations of the Scientific Advisory Group for Emergencies (SAGE) were initially secret until a press leak forced transparency.

12.11.2020 - 11:12 [ HeraldScotland.com ]

Top Scots academic warns ministers not to prioritise Pfizer vaccine

The vaccine, which is thought to be effective against Covid-19 in nine out of 10 people, could be ready for distribution by next month but it needs to be stored at -80C for it to work.

This ‚ultra-cold‘ state is part of the logistical challenge facing the country, particularly if the vaccine is manufactured overseas.

The professor, from the university’s Centre for Sustainable Road Freight, explained that it may make more sense to prioritise the AstraZenica Oxford vaccine which can be made in the UK.

12.11.2020 - 11:09 [ Mark Sanders / Twitter ]

So the Pfizer vaccine is expected to be up to seven times more expensive than the Oxford one, reports the Times.

Welcome to profit first, morals later America.

12.11.2020 - 11:01 [ eastdevonwatch.org ]

Oxford v Pfizer: how costs and logistics could still see Oxford’s vaccine win out

Matt Hancock has warned the mass distribution would be a “colossal exercise” involving not just the NHS but the Armed Forces.

The Health Secretary acknowledged there was “enormous complexity” in administering the Pfizer vaccine.

12.11.2020 - 10:06 [ theGuardian.com ]

Vaccine taskforce chief may benefit from £49m UK investment

She is expected to leave her post at the end of the year, according to a government source who said her contract ran until January 2021 and she had always intended to leave at that point.

12.11.2020 - 09:26 [ NPR.org ]

Pfizer CEO Sold Millions In Stock After Coronavirus Vaccine News, Raising Questions

Daniel Taylor, an expert in insider trading and an associate professor of accounting at the Wharton School of the University of Pennsylvania, has closely monitored stock trades by executives at companies developing coronavirus vaccines. He told NPR that the close timing between the adoption of Bourla’s stock plan and the press release looked „very suspicious.“

„It’s wholly inappropriate for executives at pharmaceutical companies to be implementing or modifying 10b5-1 plans the business day before they announce data or results from drug trials,“ Taylor said.

10.11.2020 - 17:51 [ Boris Johnson, Prime Minister of the United Kingdom / Twitter ]

Huge thanks to Kate Bingham and the Vaccine Taskforce for all their fantastic work in securing 40 million doses of the @pfizer & @BioNTech_Group vaccine and over 300 million doses of other promising vaccine candidates.

10.11.2020 - 17:36 [ Keir Shiels / Twitter ]

This vaccine needs to be kept at below -80 ^C because it uses mRNA. Not suitable for most clinics and GP practices. My money is still on Oxford to produce a more effective and ergonomic one.

07.11.2020 - 14:21 [ Reuters ]

COVID vaccine deliveries on ice as AstraZeneca awaits trial data

(05.11.2020)

A summer dip in UK coronavirus infections has pushed back test results for AstraZenca’s potential COVID-19 vaccine, leading the drugmaker to delay deliveries of shots to the UK government.

06.11.2020 - 18:15 [ DailyMail.co.uk ]

Downing Street REJECTS calls to end lockdown despite four more sets of real-world data showing second wave of Covid was dropping and R rate was stable BEFORE crippling restrictions based on flawed projections

Downing Street today refused calls for England’s second lockdown to be cut short and insisted it will run until December 2, despite four more sets of real-world data that show the second wave was already shrinking before the Government pushed the panic button on a drastic month-long shutdown.

Promising figures published today by the Office for National Statistics (ONS) – which runs a massive government surveillance scheme that randomly swabs tens of thousands of people to track the size of the outbreak – suggest that the country’s coronavirus outbreak has shrunk.

06.11.2020 - 13:35 [ Telegraph.co.uk ]

Exclusive: ‚Covid graphs were wrong in suggesting daily deaths would soon surpass first wave‘

Official projections which pushed the country into a second lockdown have been quietly revised to no longer suggest deaths could soon overtake those at the peak of the first wave, The Telegraph has learned.

03.11.2020 - 14:59 [ DailyMail.co.uk ]

More proof England’s lockdown was premature? Top researchers say R rate has dropped to 1 as Oxford expert claims Covid infections are ‚flatlining‘ and the ‚4,000 deaths‘ graph used to justify restrictions has ‚proven to be incorrect‘

– King’s College London said cases were now ‚plateauing‘ and there was a ’slight fall‘ in infections across UK
– Oxford’s Carl Heneghan said told how coronavirus hospital admissions, cases and ‚in effect‘ deaths in retreat
– It comes as Sir Patrick Vallance and Prof Chris Whitty face questions from MPs over the 4,000 deaths figure

03.11.2020 - 14:49 [ DailyMail.co.uk ]

Is the NHS actually QUIETER than usual? Leaked document claims hospitals are 84% full (but last autumn the figure was 92%)

– Beds have never been less than 85% full for a three-month period since 2010
– Spring this year was the first time, because patients were turfed out for Covid-19
– And occupancy remains below average levels despite second wave, stat shows

02.11.2020 - 15:38 [ DailyMail.co.uk ]

How Vallance’s secret blood-curdling press briefing on looming lockdown – an hour BEFORE Boris agreed to it – lit the fuse on Nov 5th shutdown that could blow up our economy

– Boris Johnson announced England-wide lockdown after weeks insisting he would stick to his local ‚Tiers‘
– The PM summoned a dramatic press conference Saturday night after details of the U-turn idea were leaked
– Sir Patrick Vallance gave blood-curdling briefing about the situation on Friday before ministers made decision
– More details were then leaked overnight before the wider Cabinet had been gathered, forcing the PM’s hand
Mr Johnson is set to use a statement to the House of Commons this afternoon to say there is ’no alternative‘

02.11.2020 - 15:33 [ DailyMail.co.uk ]

Apocalyptic forecast of 4,000 coronavirus deaths a day could be FIVE TIMES too high and had already been proved wrong when government revealed it at weekend

– Sir Patrick Vallance presented worst-case scenario in Saturday’s briefing when lockdown was confirmed
– But it has emerged it was based on forecasts made weeks ago and since updated to give lower estimates
– Oxford’s Carl Heneghan said he was ‚concerned‘ at officials‘ choice to use old data which could be misleading
– Tory MPs accused SAGE, of which Vallance is chair, of ‚cherry-picking‘ figures and not giving full picture
– England will be thrust into a second lockdown from Thursday, pending a vote in Parliament on Wednesday

01.11.2020 - 18:24 [ Telegraph.co.uk ]

Coronavirus latest news: Boris Johnson faces Tory rebellion over national lockdown

Boris Johnson faces a rebellion from his backbenches over the new national lockdown restrictions for England amid warnings that the measures would be „disastrous“ for the economy.

This comes after Cabinet Minister Michael Gove admitted the four-week-long national lockdown could be extended beyond December 2.

01.11.2020 - 18:18 [ CNN ]

Boris Johnson accused of ‚giving in to scientific advisers‘ as England heads for lockdown

Former Conservative leader Iain Duncan Smith wrote in the UK’s Telegraph newspaper that the month-long lockdown showed government was „giving in to the scientific advisers,“ claiming that government experts had „pressurised“ Johnson into the step.

„Normally, advisers advise and ministers decide. Yet that system has broken down with Sage [the Scientific Advisory Group for Emergencies] believing its advice to be more like commandments written on stone and its members publicly lecturing the Government over the airways,“ Duncan Smith wrote.

30.10.2020 - 13:20 [ DailyMail.co.uk ]

German Pfizer vaccine could be ready before Oxford-AstraZeneca injection and be given to Brits before Christmas

Ms Bingham was appointed chair of the UK’s Vaccine Taskforce for Covid-19 in May and reports directly to the Prime Minister on the progress of a coronavirus vaccine, which experts say is key to controlling the pandemic.

The taskforce, which Ms Bingham says was the ‚brainchild of Sir Patrick Vallance‘ — Number 10’s chief scientific adviser, is at the forefront of putting plans in place to get the UK population vaccinated.

29.10.2020 - 05:51 [ marketscreener.com ]

EU warns not enough COVID vaccines for all in Europe until 2022

(27.10.2020)

The EU has so far secured doses of the potential vaccines being developed by AstraZeneca, Sanofi and Johnson & Johnson. It has also said it is in talks with …

29.10.2020 - 05:31 [ Bloomberg ]

Astra-Oxford Vaccine Stays Near Front of Line Despite U.S. Delay

A seven-week halt to a U.S. trial of the Covid vaccine developed by AstraZeneca Plc and the University of Oxford bumped it from pole position in the race for a protective shot, but it’s still in the leading pack.

26.10.2020 - 17:20 [ CNBC ]

AstraZeneca says its coronavirus vaccine triggers immune response among adults

“It is encouraging to see immunogenicity responses were similar between older and younger adults and that reactogenicity was lower in older adults, where the COVID-19 disease severity is higher,” an AstraZeneca spokesman told CNBC via email.

“The results further build the body of evidence for the safety and immunogenicity of AZD1222,” the spokesman said, referring to the technical name of the Oxford-AstraZeneca vaccine.

26.10.2020 - 17:19 [ CNN ]

It took AstraZeneca researchers 1 month to get vaccine trial data to FDA, source tells CNN

(14.10.2020)

The source said the root of the delay is that the participant was in the United Kingdom, and the European Medicines Agency and the FDA store data differently.

„They had to convert data from one format to another format. It’s like taking stuff off a PC and putting it onto an Apple. They had to spend a lot of hours to get what they wanted,“ the source said.

26.10.2020 - 17:17 [ Statnews.com ]

As AstraZeneca’s Covid-19 vaccine trial remains on hold in U.S., participants waiting on a second dose are in limbo

(06.10.2020)

Still, such participants occupy an unusual position in a trial shutdown that is being closely watched as a potential indicator of the prospects of a frontrunner in the race to develop a vaccine to curb the devastation of the Covid-19 pandemic.

For the participant who spoke with STAT — and others in his same position who can’t currently get their booster shot — the trial halt has become a waiting game. “Now, we’re waiting as the lab rats in the corner,” said the participant, who requested anonymity because he was worried he could face consequences if study investigators found out he had spoken to the press.

24.10.2020 - 10:40 [ apnews.com ]

AstraZeneca, J&J resuming US tests of COVID-19 vaccines

The two coronavirus vaccines are among several candidates in final-stage testing, the last step before seeking regulatory approval.

The drugmakers said they got the go-ahead Friday from the Food and Drug Administration to restart tests in the U.S.

23.10.2020 - 11:34 [ University of Bristol ]

Oxford COVID-19 vaccine follows its programmed genetic instructions, independent analysis finds

The AstraZeneca Oxford COVID-19 vaccine (ChAdOx1 nCoV-19 and also known as AZD1222) now undergoing Phase III clinical trials, has already undergone rigorous testing to ensure the highest standards of quality and safety. Now a team at Bristol University has used recently developed techniques to further validate that the vaccine accurately follows the genetic instructions programmed into it by the Oxford team. This novel analysis provides even greater clarity and detail about how the vaccine successfully provokes a strong immune response.

14.10.2020 - 12:37 [ ukcolumn.org ]

Covid-19: The Data Exposing the Deception

Without a functioning mainstream media, and with government scientific advisors seemingly bought and paid for by pharmaceutical corporations, it has been left to independent journalists and researchers to question the Covid-19 narrative that we are all supposed to accept without hesitation. Few have worked harder than Mark Oakford.

Mark has sent 1,392 freedom of information requests to local authorities, Clinical Commissioning Groups, NHS trusts, Police Forces, Education Authorities, Ministerial departments and more.

While a few requests remain unanswered, he has gathered data on more than 1.6 million public sector workers across the UK…

(…)

We are told that lockdowns are essential to avert a so-called second wave. Yet Mark found, for public sector workers who regularly interact with the public in the community, such as police officers, fire officers, park attendants and so forth, mortality was zero.

Our entire way of life is being irrevocably changed because of the claims made about Covid-19. We should insists that those claims be rigorously scrutinised.

14.10.2020 - 02:13 [ Keep Talking Greece ]

Crete: Murderer of US biologist Suzanne Eaton gets life sentence

The body 60-year-old Suzanne Eaton, who was in Chania on Crete to attend a conference, was found nearly 10 km away from her hotel, a week after she was reported missing.

07.10.2020 - 12:27 [ BBC ]

Genome editing wins Nobel chemistry prize

Her work showed that tracrRNA is part of the organism’s immune defences.

This system, known as CRISPR/Cas, disarms viruses by cleaving their DNA.

In 2011, the same year she published this work, Charpentier began a collaboration with Doudna to recreate the bacterium’s genetic scissors in a test tube. They also worked on simplifying the scissors‘ molecular components so they were easier to use.

20.09.2020 - 17:43 [ Prof Michel Chossudovsky / Global Research ]

What is Covid-19, SARS-2. How is it Tested? How is It Measured? The Fear Campaign Has No Scientific Basis

The data and concepts have been manipulated with a view to sustaining the fear campaign.

The estimates are meaningless. The figures have been hyped to justify the lockdown and the closure of the national economy, with devastating economic and social consequences. The Virus is held responsible for poverty and mass unemployment.

Confirmed by prominent scientists as well as by official public health bodies including the World Health Organization (WHO) and the US Center for Disease Control and Prevention (CDC). Covid-19 is a public health concern but it is NOT a dangerous virus.

The COVID-19 crisis is marked by a public health “emergency” under WHO auspices which is being used as a pretext and a justification to trigger a Worldwide process of economic, social and political restructuring. Social engineering is being applied. Governments are pressured into extending the lockdown, despite its devastating economic and social consequences.

There is no scientific basis for implementing the closing down of the global economy as a means to resolving a public health crisis.

Both the media and the governments are involved in spreading disinformation.

02.09.2020 - 13:12 [ Times of India ]

In change of tack, EU leaves door open to COVID vaccines purchase through WHO

The move could allow EU governments to secure vaccines from companies that are not negotiating with Brussels, such as U.S. firms Merck, Inovio and Novavax. They are all in talks with the WHO scheme, dubbed COVAX, but have so far not been reported to be involved in negotiations with the EU Commission.

15.08.2020 - 16:28 [ Matt Taibbi / Rolling Stone ]

Big Pharma’s Covid-19 Profiteers

How the race to develop treatments and a vaccine will create a historic windfall for the industry — and everyone else will pay the price

12.08.2020 - 19:18 [ Sputniknews.com ]

Forbidden Op-Ed: The Sputnik Vaccine as a Lifesaving Global Partnership

The use of two vectors is the unique technology, developed by the Gamaleya Center scientists, which differentiates the Russian vaccine from other adenoviral vector-based vaccines under development around the world. Vaccines based on adenoviral vectors also have clear advantages over other technologies such as mRNA vaccines.

Prospective mRNA vaccines, undergoing clinical trials in the United States and other countries, do not use vectors for delivery and represent an RNA molecule with coronavirus protein code wrapped in a lipid membrane. This technology is promising but its side effects, especially an impact on fertility, have not yet been studied in depth. No mRNA vaccine has yet received regulatory approval in the world.

12.08.2020 - 19:16 [ CNBC ]

Russia wealth fund head: Sputnik V vaccine could be delivered by November or December

„We were just fortunate that the coronavirus was very close to MERS, so we pretty much had a ready-to-go vaccine on MERS, studied for two years on MERS (and) slightly modified to be the coronavirus vaccine, and that is the real story, no politics … Russia has always been at the forefront of vaccine research,“ Kirill Dmitriev, CEO of Russia’s sovereign wealth fund RDIF, which is backing the vaccine, told CNBC.

The World Health Organisation states that no vaccine or treatment for MERS is currently available, but says that there are several in development.

04.08.2020 - 02:20 [ Reuters ]

AstraZeneca to be exempt from coronavirus vaccine liability claims in most countries

July 30, 2020

AstraZeneca has been granted protection from future product liability claims related to its COVID-19 vaccine hopeful by most of the countries with which it has struck supply agreements, a senior executive told Reuters.

30.07.2020 - 02:28 [ Foreigner.fi ]

EU buys 30,000 doses of remdesivir to treat severe Covid-19 cases

Remdesivir is the first drug that received EU approval for coronavirus treatment.

20.07.2020 - 17:39 [ Bloomberg ]

U.K. Orders 90 Million Vaccine Doses from Pfizer and Valneva

“It’s the right thing to be doing to be at the absolute front of the queue to make sure we’re in a position to get those vaccines first when they become available,” Education Secretary Gavin Williamson told the BBC during the government’s media round on Monday.

20.07.2020 - 17:31 [ Telegraph.co.uk ]

Oxford coronavirus vaccine is safe and induces immune reaction, findings suggest

Initial trials on 1,077 British adults found that the vaccine induced strong antibody and T-cell responses, which may improve further after a booster jab, as reported by the Telegraph.

There were found to be no serious adverse events, and minor side effects could be controlled by paracetamol, two papers in The Lancet reported.

12.07.2020 - 15:33 [ DailyMail.co.uk ]

Scientists from the Wuhan virus lab have ‚defected‘ to the West, reveals senior Trump ally Steve Bannon – as FBI gathers evidence that coronavirus pandemic was caused by an accidental leak

He said: ‘The thing was built with French help, so don’t think that there aren’t some monitoring devices in there. I think what you are going to find out is that these guys were doing experiments which they weren’t fully authorised [for] or knew what they were doing and that somehow, either through an inadvertent mistake, or on a lab technician, one of these things got out.

‘It’s not that hard for these viruses to get out. That is why these labs are so dangerous.

‘You essentially had a biological Chernobyl in Wuhan, but the centre of gravity, the Ground Zero, was round the Wuhan lab, in terms of the casualty rates. And like Chernobyl, you also had the cover-up – the state apparatus reports to itself and just protects itself.’

11.07.2020 - 18:33 [ theGrayzone.com ]

Why the Bill Gates global health empire promises more empire and less public health

Behind a veil of corporate media PR, the Gates Foundation has served as a vehicle for Western capital while exploiting the Global South as a human laboratory. The coronavirus pandemic is likely to intensify this disturbing agenda.

09.07.2020 - 19:13 [ Raul Diego / Mint Press ]

Fourth Reich? Mass-Tracking COVI-PASS Immunity Passports Slated to Roll Out in 15 Countries

COVI-PASS will determine whether you can go to a restaurant, if you need a medical test, or are due for a talking-to by authorities in a post-COVID world. Consent is voluntary, but enforcement will be compulsory.

05.07.2020 - 15:55 [ Prof Michel Chossudovsky / Global Research ]

COVID-19 Coronavirus “Fake” Pandemic: Timeline and Analysis

First published on April 8, 2020

Timeline from September 2019 – April 2020

03.07.2020 - 20:59 [ Nasdaq.comMers ]

Why Gilead Sciences Shares Rose 18.4% in the First Half

Early into the health crisis, Gilead began testing remdesivir as a possible treatment for the illness caused by the novel coronavirus. The antiviral initially had been studied in other coronaviruses — severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). More recently, remdesivir entered clinical trials for COVID-19, and as promising data emerged, the U.S. Food and Drug Administration granted the drug Emergency Use Authorization.

03.07.2020 - 20:57 [ Forbes ]

Could Gilead Stock Get A Boost From Inhaled Remdesivir? Great Speculations

(26.06.2020)

Separately, Gilead also provided updates on its production plans for the drug, noting that it expects to have over two million Remdesivir treatment courses manufactured by the end of 2020, with the number rising further over 2021, as it optimizes the manufacturing process.

For more details on the stock price and fundamental performance of some of the key U.S. listed companies developing coronavirus therapeutics, view our theme of Covid-19 Treatment Stocks.

02.07.2020 - 16:23 [ BBC ]

Coronavirus: Could ‚immunity passports‘ create an antibody elite?

Getting to that „new normal“ as quickly as possible is the target for governments around the globe, Many find antibody-testing the entire population a tantalising idea where infection rates are high.

In Germany, the country’s disease control and prevention agency, the Robert Koch Institute, is conducting large-scale random antibody testing.

25.06.2020 - 19:23 [ Politico.com ]

House members, Senate aides traded stocks in early days of coronavirus

(31.03.2020)

Holmes traded out two stocks a week later, on Jan. 29, then on Feb. 27 made two purchases that could prove advantageous in the weeks ahead: Holmes purchased between $15,001 and $50,000 of stock in each of two more companies, the pharmaceutical company Gilead, Inc. — which makes remdesivir, a drug that is currently being tested to treat coronavirus — and wipe manufacturer Clorox.

25.06.2020 - 18:55 [ DailyMail.co.uk ]

Donald Rumsfeld’s controversial links to drug company behind Tamiflu

(2 May 2009)

Mr Rumsfeld, a former chairman of the company, has refused to comment on whether he still holds shares in Californian firm Gilead Sciences, which developed the drug now being desperately stockpiled by governments around the world to combat the threatened pandemic.

25.06.2020 - 18:39 [ Xinhua ]

Israel agrees to receive U.S. donation of experimental drug Remdesivir for COVID-19 treatment

(17.06.2020)

Israel will receive a donation of Remdesivir, an experimental antiviral drug for COVID-19, from its U.S. manufacturer, Israel’s prime minister’s office said on Tuesday.

The Israeli cabinet approved in a telephone vote the decision by the Health Ministry to issue a permit to accept a donation of the drug from Gilead Sciences Inc, the U.S. biopharmaceutical company that produces the drug.

25.06.2020 - 18:32 [ businesstoday.in ]

Coronavirus cure: Gilead signs pacts with 4 more firms for manufacturing of remdesivir

(14.06.2020)

Gilead Sciences Inc has signed agreements with four pharma companies, Dr Reddy’s Laboratories Ltd, Biocon arm Syngene International Ltd, Zydu Cadila Ltd and Egypt-based Eva Pharma Pvt Ltd, for manufacturing and sale of remdesivir, which has shown greater impact during initial two phases of trials. The company had previously signed pacts with five other companies including Cipla, Jubilant Life, Hetero Drugs, Mylon and Pakistan’s Ferozsons Laboratories.

17.06.2020 - 21:53 [ Xinhuanet ]

WHO expert says anti-malaria drug to be stopped from Solidarity Trial in fighting COVID-19

„Based on the analysis and on the review of the published evidence, the executive group of the Solidarity / recovery trial has … after the deliberation … concluded that hydroxychloroquine arm will be stopped from the Solidarity Trial,“ Ana Maria Henao Restrepo, Medical Officer, Department of Immunization Vaccines and Biologicals at WHO said on Wednesday at a press conference in Geneva.

27.05.2020 - 02:09 [ Global Research ]

„Globalized Wellness“: The Big Pharma COVID Vaccine Marathon

An additional (so-called) benefit of this alternative brand of vaccine technology is that, once developed, it will not require refrigeration. Naturally, this has considerable implications for wide-spread use in third world countries. Unsurprisingly, funding for this emerging variation of vaccine technology is coming from the NIH as well as the Bill and Melinda Gates Foundation.

It goes without saying that pharmaceutical companies have become so infused into our globalized wellness infrastructure to the point that we don’t even see them anymore. They have become pervasively entrenched into the background of our social fabric, and are considered as mundanely-important and essential as the plumbing in our houses and our cities. This widespread habituation has ultimately numbed our sense of collective concern to the point where we aren’t as alarmed by how their products are conceived, nor by who is ultimately funding their research and development.

27.05.2020 - 01:45 [ German Foreign Policy ]

Philanthropie als Geschäft

Dabei werden der Einsatz gefährlicher Pestizide und die Nutzung genmanipulierter Pflanzen in Ländern des globalen Südens gefördert oder die wenig profitable Entwicklung von Impfstoffen mit hohen Summen unterstützt. Kritiker monieren seit Jahren, von der Gates Foundation unterstützte Projekte zielten vor allem darauf ab, quantitativ messbare Erfolge zu erzielen – ohne Rücksicht auf ökologische Erwägungen. Zudem werden zentrale Felder der Politik demokratischer Kontrolle entzogen.

17.05.2020 - 06:31 [ Cnet.com ]

COVID-19 could set a new norm for surveillance and privacy

The outbreak has also brought new privacy issues, as companies beef up surveillance with tech like thermal cameras and facial recognition in preparation for when people return to their everyday lives.

Surveillance technology has slowly integrated into our daily lives, with facial recognition getting added as a „convenience“ feature for casinos and ordering food. The coronavirus has sped up that process, in the name of public health.

11.05.2020 - 22:01 [ Dakota Gruener / Harvard.edu ]

Immunity Certificates: If We Must Have Them, We Must Do It Right

(20.04.2020)

Credential Use:

1. When the individual attempts to gain access to, for instance, a place of work, the business will verify1.the validity of the credential, then make a determination to grant or deny access. This verification does not require contacting the issuer of the credential.

2. As part of the process of determining whether to grant or deny access, the verifier can compare the cryptographically verified photo against the individual through manual means or through automated facial recognition.

11.05.2020 - 21:38 [ ec.europa.eu ]

GLOBAL VACCINATION SUMMIT: PANEL MEMBER BIOGRAPHIES ROUNDTABLE 1: „In Vaccines we trust: Stepping up action to increase vaccine confidence”

(12.09.2019)

JASON HIRSCH, Public Policy Manager,

Jason Hirsch joined Facebook’s Public Policy team in October 2018, where he focuses on development of policies to help guide Facebook’s approach to content distribution and moderation. Within that role, Mr. Hirsch heads up Facebook’s Health Integrity Policy efforts, including leading the development of Facebook’s multi-faceted approach to combatting misinformation about vaccinations.

11.05.2020 - 21:20 [ ec.europa.eu ]

ROADMAP FOR THE IMPLEMENTATION OF ACTIONS BY THE EUROPEAN COMMISSION BASED ON THE COMMISSION COMMUNICATION AND THE COUNCIL RECOMMENDATION ON STRENGTHENING COOPERATION AGAINST VACCINE PREVENTABLE DISEASE

(March 2019)

Examine the feasibility of developing a common vaccination card/passport for EU citizens (that takes into account potentially different national vaccination schedules and), that is compatible with electronic immunisation information systems and recognised for use across borders, without duplicating work at nati

06.05.2020 - 18:03 [ InvestmentWatchblog.com ]

France Calls for ‘Health Passports” As Germany Rolls Out ‘Immunity Cards’

(02.05.2020)

The mayor of Nice has urged French PM Edouard Philippe to introduce new travel controls during the Covid-19 pandemic through “health passports” in the parts of France which border other countries.

05.05.2020 - 20:57 [ Sydney Morning Herald ]

Australian intelligence knocks back US government’s Wuhan lab virus claim

Senior members of the Australian intelligence community told The Sydney Morning Herald and The Age a research document shared in political circles under the Five Eyes intelligence arrangement was mostly based on news reports and contained no material from intelligence gathering.

05.05.2020 - 20:38 [ BBC ]

Coronavirus: US allies tread lightly around Trump lab claims

(today)

UK officials believe it is not possible to be absolutely sure about the origins but point to scientific opinion suggesting the most likely scenario is …

05.05.2020 - 20:30 [ theGuardian.com ]

Five Eyes network contradicts theory Covid-19 leaked from lab

(04.05.2020)

There is no current evidence to suggest that coronavirus leaked from a Chinese research laboratory, intelligence sources have told the Guardian, contradicting recent White House claims that there is growing proof this is how the pandemic began.

The sources also insisted that a “15-page dossier” highlighted by the Australian Daily Telegraph which accused China of a deadly cover up was not culled from intelligence from the Five Eyes network, an alliance between the UK, US, Australia, New Zealand and Canada.

05.05.2020 - 20:17 [ ABC News ]

This Week‘ Transcript 5-3-20: Mike Pompeo, Gov. Mike DeWine, Ronna McDaniel, Tom Perez

(03.05.2020)

RADDATZ: Do you believe it was manmade or genetically modified?

POMPEO: Look, the best experts so far seem to think it was manmade. I have no reason to disbelieve that at this point.

RADDATZ: Your — your Office of the DNI says the consensus, the scientific consensus was not manmade or genetically modified.

POMPEO: That’s right. I — I — I agree with that. Yes. I’ve — I’ve seen their analysis. I’ve seen the summary that you saw that was released publicly. I have no reason to doubt that that is accurate at this point.

05.05.2020 - 20:15 [ @renmin_wansui / Twitter ]

5 RADDATZ: OK, so just to be clear, you do not think it was manmade or genetically modified? POMPEO: I’ve seen what the intelligence community has said. I have no reason to believe that they’ve got it wrong.

05.05.2020 - 20:11 [ New York Times ]

Pompeo Ties Coronavirus to China Lab, Despite Spy Agencies’ Uncertainty

Speaking on the ABC program “This Week,” Mr. Pompeo, the former C.I.A. chief and one of the senior administration officials who is most hawkish on dealing with China, said that “there’s enormous evidence” that the coronavirus came from the lab, though he agreed with the intelligence assessment that there was no indication that the virus was man-made or genetically modified.

05.05.2020 - 13:29 [ CNN ]

Intel shared among US allies indicates virus outbreak more likely came from market, not a Chinese lab

The third source said it is also possible the US is not sharing all of its intelligence. While the overwhelming majority is shared among the Five Eyes members, there are pockets of information that each country keeps to itself.