Archiv: CRISPR (genetic engineering technique)


07.10.2020 - 12:27 [ BBC ]

Genome editing wins Nobel chemistry prize

Her work showed that tracrRNA is part of the organism’s immune defences.

This system, known as CRISPR/Cas, disarms viruses by cleaving their DNA.

In 2011, the same year she published this work, Charpentier began a collaboration with Doudna to recreate the bacterium’s genetic scissors in a test tube. They also worked on simplifying the scissors‘ molecular components so they were easier to use.

14.01.2020 - 14:27 [ Claire Robinson / GMWatch ]

Researchers assumed CRISPR-mediated disruption of genes was turning them off – but they were wrong

A new study reveals yet another major unintended effect from the CRISPR-Cas9 gene editing tool – with potentially serious implications for the food safety of gene-edited plants. The study found that CRISPR-Cas9 edits intended to knockout the function of a gene fail to do so. Instead, proteins are still produced from the damaged genes, many of which are still functional. The result could be the production of gene-edited plants that are toxic or allergenic.

14.01.2020 - 14:26 [ Radio Utopie ]

US-Militärbehörde D.A.R.P.A. weltweit größter Förderer der „Gen-Drive“-Forschung

6.12.2017

Forschungsbehörde des Verteidigungsministeriums der Vereinigten Staaten von Amerika, D.A.R.P.A., weltweit größter Förderer der „Gen-Drive“-Forschung (Genome Editing und CRISPR-Cas9)

U.S.-Geheimdienstkreise sehr interessiert.

04.12.2019 - 16:21 [ MIT Technology Review ]

China’s CRISPR babies: Read exclusive excerpts from the unseen original research

He Jiankui’s manuscript shows how he ignored ethical and scientific norms in creating the gene-edited twins Lulu and Nana.

04.12.2019 - 16:16 [ South China Morning Post ]

Gene-edited babies: Chinese scientist He Jiankui ‘may have created unintended mutations’

Despite biophysicist’s claims, team failed to reproduce changes to make twin girls HIV immune, excerpts from manuscript show
Birth of gene-edited babies Lula and Nana sent shock waves through scientific world in 2018

21.07.2018 - 19:20 [ Japan Today ]

Gene-editing damages DNA more than previously thought: study

They found „large genetic rearrangements such as DNA deletions and insertions“ in cells, which could lead to important genes being switched on or off and causing dangerous changes.

The research also showed that standard tests do not pick up damage to DNA caused by CRISPR-Cas9.

Experts not involved in the study said it was unclear how such large, unintended changes were not noticed before.

06.12.2017 - 06:56 [ Wikipedia ]

CRISPR/Cas-Methode

Die CRISPR/Cas-Methode (Clustered Regularly Interspaced Short Palindromic Repeats) ist eine biochemische Methode, um DNA gezielt zu schneiden und zu verändern (Genome Editing). Gene können mit dem CRISPR/Cas-System eingefügt, entfernt oder ausgeschaltet werden,[1] auch Nukleotide in einem Gen können geändert werden.[2]

01.05.2016 - 14:24 [ Informationsdienst Gentechnik ]

Kein CRISPR bei Demeter

Gentechnisch veränderte Pflanzen haben in der Bio-Landwirtschaft nichts zu suchen – auch dann nicht, wenn es um ganz neue Gentech-Verfahren wie CRISPR/Cas, Zinkfingernuklease-Technik oder Oligonukleotid-gesteuerte Mutagenese geht. Daran ließen die Delegierten des Anbauverbandes Demeter bei ihrer jährlichen Versammlung keinen Zweifel.

12.04.2016 - 13:45 [ TechinAsia ]

Chinese scientists are changing what it means to be human. We need to think about the downsides.

Still, this experiment and last year’s are a proof of concept: CRISPR could be used to introduce desired genetic mutations into a human embryo. And if that embryo was viable and was implanted into a uterus and carried to term, the resulting child would be something out of science fiction: a genetically-enhanced human being.