Archiv: CRISPR (genetic engineering technique)

26.10.2022 - 07:50 [ ]

Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2


The goal of this paper is to address the question whether SARS-CoV-2 originated from an animal-to-human spillover or from experiments performed in a laboratory. In the latter scenario, it is possible that evidence exists for manipulation of the viral genome by common laboratory techniques. SARS-CoV-2 is a large RNA virus. To create infectious versions of CoVs, the entire 30kb RNA genome is reconstructed in DNA by in vitro genome assembly (IVGA). IVGA has been used to create reverse genetic systems for modified and chimeric RNA viruses for more than 20 years (Yount et al, 2000). Most importantly, IVGA methods can leave genetic fingerprints, and we find those fingerprints in the genome of SARS-CoV-2.

29.03.2022 - 06:16 [ ]

CRISPR gene-editing experiment may have impacted twins‘ brains

(February 21, 2019)

But no one knows how the method may have affected the minds of the Chinese twins at the center of the issue. One scientist involved in the study, University of California, Los Angeles neurobiologist Alcino J. Silva, said the „mutations will probably have an impact on cognitive function,“ but it’s impossible as yet to predict the precise effects. The CRISPR-Cas9 gene-editing technique has previously been linked with unintended DNA damage.

29.03.2022 - 06:10 [ Massachusetts Institute of Technology (MIT) ]

China’s CRISPR twins might have had their brains inadvertently enhanced

(February 21, 2019)

The twins, called Lulu and Nana, reportedly had their genes modified before birth by a Chinese scientific team using the new editing tool CRISPR. The goal was to make the girls immune to infection by HIV, the virus that causes AIDS.

Now, new research shows that the same alteration introduced into the girls’ DNA, deletion of a gene called CCR5, not only makes mice smarter but also improves human brain recovery after stroke, and could be linked to greater success in school.

29.03.2022 - 05:49 [ Alliance for Natural Health ]

The WHO pandemic treaty: a backdoor to global governance?

(23 February 2022)

If the pandemic treaty were to come into effect in 2024, you can guarantee even higher global health surveillance using real-time sequencing for both diagnostics and epidemiology. This would be based on ever-more portable technologies with increasingly rapid turnaround times.

But don’t just think mRNA injections or intranasals. Or gene editing technologies based on CRISPR for diagnostics. Think CRISPR to enhance the immune response will likely see an entry. This is a facet of transhumanism, as is digital surveillance.

29.03.2022 - 05:00 [ Genetic Engineering & Biotechnology News ]

A CRISPR Kitty? Gene Editing Breathes New Life into the Hypoallergenic Cat

As described by Sarah Zhang in The Atlantic, applying biotechnology to tackle cat allergies is not a new feat. From immunity transfer using egg-yolk coating on Purina’s cat food to cat vaccines that reduce shedding of Fel d 1, the goal of a true hypoallergenic cat remains on the industry’s radar. Is CRISPR genetic therapy next on the list?

29.03.2022 - 04:20 [ ]

Gentechnikerinnen basteln an allergenfreien Katzen

Die Sequenzen unterscheiden sich relativ stark, das Gen ist aus evolutionärer Sicht also nicht allzu stabil – und somit auch nicht allzu bedeutsam für die Katzen. Und das macht es zu einem Kandidaten für die „Genschere Crispr“, die die Biotechnologie seit einigen Jahren revolutioniert hat. Mit Crispr können Forscherinnen und Forscher das Erbgut verändern und etwa unliebsame Abschnitte herausschneiden.

04.12.2021 - 17:11 [ RAND Corporation ]

What Is the Internet of Bodies?


Mary Lee, Mathematician; Fellow, RAND Center for Global Risk and Security

The Internet of Bodies, or IoB, is actually an ecosystem. It’s a bunch of devices that are connected to the Internet that contain software and that either collect personal health data about you or can alter the body’s function. We think of the Internet of Bodies as this collection of all these devices, as well as all the data that the devices are gathering about you. And in health care, Internet of Bodies has been around for quite a while. With the advent of the Internet, it makes a lot of sense to connect your pacemaker to the Internet so that your doctor can be automatically notified if something weird happens, if there’s an anomaly. It’s natural in a lot of ways to want to understand more about your body, how it functions, how well it’s doing.

04.12.2021 - 16:55 [ Rubikon ]

Genetisch vernetzt

Die naturwissenschaftliche Fachzeitschrift „Nature“ veröffentlichte im Juni 2020 einen Beitrag, der den elektronischen Anschluss auf Gen-Ebene an das „Internet der Körper“ (IOB) beinhaltet. Das IOB wird vom Weltwirtschaftsforum — zusammen mit dem Great Reset — und der Gesundheitsindustrie forciert und ist verzahnt mit ID2020, GAVI sowie mit der Manipulation aller Menschen auf Erbgut-Ebene zu „Gesundheitszwecken“ und „Pandemiebekämpfung“. Diese Ziele stellte die WHO im Juli 2021 der Öffentlichkeit vor.

29.05.2021 - 15:13 [ ]

EXCLUSIVE: COVID-19 ‚has NO credible natural ancestor‘ and WAS created by Chinese scientists who then tried to cover their tracks with ‚retro-engineering‘ to make it seem like it naturally arose from bats, explosive new study claims

– An explosive new study claims researchers found ‚unique fingerprints‚ in COVID-19 samples that they say could only have arisen from manipulation in a laboratory

– exclusively obtained the new 22-page paper authored by British Professor Angus Dalgleish and Norwegian scientist Dr. Birger Sørensen set to be published in the Quarterly Review of Biophysics Discovery

– The study showed there’s evidence to suggest Chinese scientists created the virus while working on a Gain of Function project in a Wuhan lab

– Gain of Function research, which was temporarily outlawed in the US, involves altering naturally-occurring viruses to make them more infectious in order to study their potential effects on humans
According to the paper, Chinese scientists took a natural coronavirus ‚backbone‘ found in Chinese cave bats and spliced onto it a new ’spike‘, turning it into the deadly and highly transmissible COVID-19

– The researchers, who concluded that COVID-19 ‚has no credible natural ancestor‚, also believe scientists reverse-engineered versions of the virus to cover up their tracks.

‚We think that there have been retro-engineered viruses created,‘ Dalgleish told ‚They’ve changed the virus, then tried to make out it was in a sequence years ago.‘

09.12.2020 - 19:34 [ ]

How Nanotechnology Helped Create mRNA COVID-19 Vaccines


Vaccines that employ mRNA were in early development before COVID-19 brought the world to its knees, and nanotech has been central to these efforts — unsurprisingly, as viruses are just naturally occurring nanoparticles themselves.

The key to making effective nanoparticle vaccines, and medicines in general, lies in mimicking the natural behaviors and tricks that make viruses so successful, and dangerous, in the first place.

09.12.2020 - 19:32 [ ]

Fact check: Lipid nanoparticles in a COVID-19 vaccine are there to transport RNA molecules

False. The lipid nanoparticles in the Pfizer-BioNTech COVID-19 vaccine protect and transport the vaccine component. They do not contain little computers or robots.

This article was produced by the Reuters Fact Check team. Read more about our work to fact-check social media posts here .

09.12.2020 - 19:30 [ ]

Video shares false claim that Pfizer-BioNTech Covid-19 vaccine contains ’nanotechnology‘

A video viewed thousands of times in multiple posts on Facebook claims Pfizer-BioNTech’s Covid-19 mRNA vaccine contains lipid nanoparticles that could be concealing „little computers”. The claims are false; nanoparticles are microscopic particles that measure less than 100 nanometres, which have no relation to nanocomputers; an infectious diseases expert told AFP no technology currently exists by which computers could be inserted into an mRNA vaccine.

07.10.2020 - 12:27 [ BBC ]

Genome editing wins Nobel chemistry prize

Her work showed that tracrRNA is part of the organism’s immune defences.

This system, known as CRISPR/Cas, disarms viruses by cleaving their DNA.

In 2011, the same year she published this work, Charpentier began a collaboration with Doudna to recreate the bacterium’s genetic scissors in a test tube. They also worked on simplifying the scissors‘ molecular components so they were easier to use.

14.01.2020 - 14:27 [ Claire Robinson / GMWatch ]

Researchers assumed CRISPR-mediated disruption of genes was turning them off – but they were wrong

A new study reveals yet another major unintended effect from the CRISPR-Cas9 gene editing tool – with potentially serious implications for the food safety of gene-edited plants. The study found that CRISPR-Cas9 edits intended to knockout the function of a gene fail to do so. Instead, proteins are still produced from the damaged genes, many of which are still functional. The result could be the production of gene-edited plants that are toxic or allergenic.

14.01.2020 - 14:26 [ Radio Utopie ]

US-Militärbehörde D.A.R.P.A. weltweit größter Förderer der „Gen-Drive“-Forschung


Forschungsbehörde des Verteidigungsministeriums der Vereinigten Staaten von Amerika, D.A.R.P.A., weltweit größter Förderer der „Gen-Drive“-Forschung (Genome Editing und CRISPR-Cas9)

U.S.-Geheimdienstkreise sehr interessiert.

04.12.2019 - 16:21 [ MIT Technology Review ]

China’s CRISPR babies: Read exclusive excerpts from the unseen original research

He Jiankui’s manuscript shows how he ignored ethical and scientific norms in creating the gene-edited twins Lulu and Nana.

04.12.2019 - 16:16 [ South China Morning Post ]

Gene-edited babies: Chinese scientist He Jiankui ‘may have created unintended mutations’

Despite biophysicist’s claims, team failed to reproduce changes to make twin girls HIV immune, excerpts from manuscript show
Birth of gene-edited babies Lula and Nana sent shock waves through scientific world in 2018

21.07.2018 - 19:20 [ Japan Today ]

Gene-editing damages DNA more than previously thought: study

They found „large genetic rearrangements such as DNA deletions and insertions“ in cells, which could lead to important genes being switched on or off and causing dangerous changes.

The research also showed that standard tests do not pick up damage to DNA caused by CRISPR-Cas9.

Experts not involved in the study said it was unclear how such large, unintended changes were not noticed before.

06.12.2017 - 06:56 [ Wikipedia ]


Die CRISPR/Cas-Methode (Clustered Regularly Interspaced Short Palindromic Repeats) ist eine biochemische Methode, um DNA gezielt zu schneiden und zu verändern (Genome Editing). Gene können mit dem CRISPR/Cas-System eingefügt, entfernt oder ausgeschaltet werden,[1] auch Nukleotide in einem Gen können geändert werden.[2]

01.05.2016 - 14:24 [ Informationsdienst Gentechnik ]

Kein CRISPR bei Demeter

Gentechnisch veränderte Pflanzen haben in der Bio-Landwirtschaft nichts zu suchen – auch dann nicht, wenn es um ganz neue Gentech-Verfahren wie CRISPR/Cas, Zinkfingernuklease-Technik oder Oligonukleotid-gesteuerte Mutagenese geht. Daran ließen die Delegierten des Anbauverbandes Demeter bei ihrer jährlichen Versammlung keinen Zweifel.

12.04.2016 - 13:45 [ TechinAsia ]

Chinese scientists are changing what it means to be human. We need to think about the downsides.

Still, this experiment and last year’s are a proof of concept: CRISPR could be used to introduce desired genetic mutations into a human embryo. And if that embryo was viable and was implanted into a uterus and carried to term, the resulting child would be something out of science fiction: a genetically-enhanced human being.