Archiv: Oxford University


22.03.2021 - 16:49 [ DailyMail.co.uk ]

Boris ‚will offer to SHARE millions of doses of AstraZeneca’s jab made at Dutch factory with the EU‘ as he warns a THIRD Covid wave will ‚wash up on our shores‘ from Europe

The PM is appealing to other leaders in a bid to resolve the crisis without a clash, and he spoke with continental heavyweights Angela Merkel and Emmanuel Macron last night to try and persuade them to soften their stance. He has also sent Lord Lister, a government ally, to India to ease tensions over the delay to a batch of five million UK-bound doses of the same vaccine.

16.03.2021 - 11:44 [ Boris Johnson - Gov.uk ]

PM Boris Johnson: The Oxford vaccine shows why we and the world need Britain to be global

The objective of Global Britain is not to swagger or strike attitudes on the world stage. It is to use the full spectrum of our abilities, now amplified by record spending on both defence and science, to engage with and help the rest of the world. That is how we serve the British interest, and I mean the economic interest of people up and down the country. And as the vaccine programme begins to inspire a new global hope, we want to use this moment to heal, both literally and figuratively.

17.02.2021 - 17:05 [ Spiegel ]

Spahn gibt neue Daten bekannt: Anteil britischer Mutante in Deutschland bei mehr als 20 Prozent

Die ansteckendere Corona-Variante aus Großbritannien macht bei den Neuinfektionen in Deutschland mittlerweile einen deutlich größeren Anteil aus. Laut Gesundheitsminister Spahn könnte sie bald dominierend sein.

17.02.2021 - 16:45 [ Jasmine the European Cat / Twitter ]

But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce.

(09.02.2021)

It expects to have a vaccine designed to address the variant discovered in South Africa ready by autumn.

17.02.2021 - 16:35 [ usatodaysun.com ]

AstraZeneca expects updated COVID-19 vaccine by autumn

(14.02.2021)

The Anglo-Swedish company, which makes a vaccine developed by the University of Oxford, said it is working with the university’s scientists to adapt the shot to combat new variants.

17.02.2021 - 16:31 [ MSN.com ]

Masks and social distancing could stay until AUTUMN at earliest – sources

(12.02.2021)

SAGE member Professor John Edmunds painted a darker picture and suggested the measures could last even longer.

He told ITV’s Peston face masks could be required „probably forever“ if COVID-19 becomes endemic in the UK.

17.02.2021 - 16:22 [ DailyMail.co.uk ]

New Covid vaccines could be made in 40 DAYS if they need updating to tackle mutated variants, taskforce chief says

Dr Dix added: ‚I think 40 days would be a real stretch but we would aim for something as good as that.

‚But certainly within 60 days and then, after that, we would start the manufacturing.‘

Manufacturing vaccines takes different amounts of time depending on the type of jab.

13.02.2021 - 19:36 [ Telegraph.co.uk ]

Oxford Covid-19 vaccine Q&A: How effective is it, and how is it different to the Pfizer vaccine?

According to new results, a single dose of the Oxford-AstraZeneca vaccine prevents two-thirds of Covid transmissions, raising hopes for the easing of restrictions by Easter.

The data, released on Feb 2, also revealed that the first jab prevents 100 per cent of hospitalisations after 22 days once an immune response has had time to develop.

12.02.2021 - 07:15 [ Politico.eu ]

Belgian plant blamed for AstraZeneca vaccine shortage says it met all deliveries

(10.02.2021)

AstraZeneca subcontracted the plant — previously owned by Novasep — to produce the drug substance of its vaccine. Volanti would not say how many doses the plant was contracted to provide. He said the plant sends its drug substance to an Italian company to be put into vials and packaged for distribution.

AstraZeneca declined to comment on Thermo Fisher’s remarks, according to Reuters.

12.02.2021 - 07:11 [ Jasmine the European Cat / Twitter ]

But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce.

(09.02.2021)

12.02.2021 - 07:07 [ theGuardian.com ]

AstraZeneca says vaccine against new Covid variants may take six months

AstraZeneca has said it could take between six and nine months to produce Covid-19 vaccines that are effective against new variants of the coronavirus, and begin administering them to the public.

09.02.2021 - 21:03 [ Jasmine the European Cat / Twitter ]

But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce.

It expects to have a vaccine designed to address the variant discovered in South Africa ready by autumn.

09.02.2021 - 20:57 [ theGuardian.com ]

How can Covid vaccines be tweaked to tackle new variants?

Production BioNTech has said it can produce a fresh vaccine within six weeks of a decision being made. But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce

09.02.2021 - 20:42 [ DailyMail.co.uk ]

Tories savage Matt Hancock over ’never-ending lockdown‘ as UK’s Covid second wave continues to shrink: Cases and deaths drop 27% with 12,364 infections and 1,052 victims – but Health Secretary warns border restrictions may still be in place until AUTUMN

But hopes the world-beating vaccine roll-out will mean lockdown curbs can be significantly eased any time soon were shot down today by Mr Hancock, who unveiled the latest suite of border curbs and warned they could last until the Autumn when booster vaccines will be available.

09.02.2021 - 12:34 [ DailyMail.co.uk ]

Britain could be trapped in lockdown cycles for several YEARS in fight with Covid variants – but staying in tougher measures for longer now will prevent new vaccine-resistant strains, SAGE scientists warn

Evidence suggests the Oxford University vaccine – the main weapon in Britain’s arsenal to combat the virus – does not stop people falling ill with the South African variant, which is feared to be spreading in the community already.

08.02.2021 - 16:22 [ DailyMail.co.uk ]

AstraZeneca is working on Covid vaccine booster ‚that will be ready by autumn‘ to beat South African strain after research showed its current version had ‚minimal‘ effect on stopping it

Professor Gilbert earlier told the BBC’s Andrew Marr Show that her team currently has ‚a version with the South African spike sequence in the works‘ with hopes it will be ready to administer by the autumn.

‚It’s not quite ready to vaccinate people with yet, but, as all of the developers are using platform technologies, these are ways of making a vaccine that are very quick to adapt,‘ she added.

07.02.2021 - 15:40 [ University of Oxford ]

Oxford coronavirus vaccine shows sustained protection of 76% during the 3-month interval until the second dose

(02.02.2021)

The authors also report further on the potential for the vaccine to reduce transmission of the virus, based on swabs obtained from volunteers in the UK arms of the trial with a 67% reduction after the first dose of the vaccine.

02.02.2021 - 23:55 [ Social Science Research Network ]

Single dose administration, and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine

If there was no impact of a vaccine on asymptomatic infection, it would be expected that an efficacious vaccine would simply convert severe cases to mild cases and mild cases to asymptomatic, with overall PCR positivity unchanged. A measure of overall PCR positivity is appropriate to assess whether there is a reduction in the burden of infection. Analyses presented here show that a single standard dose of the vaccine reduced PCR positivity by 67%, and that, after the second dose, the SD/SD schedule reduced PCR positivity by 49.5% overall. These data indicate that ChAdOx1 nCoV-19, used in the authorised schedules, may have a substantial impact on transmission by reducing the number of infected individuals in the population.

02.02.2021 - 23:55 [ DailyMail.co.uk ]

Single shot of Oxford University’s Covid jab ‚is 76% effective for 12 weeks and may block seven in 10 people from spreading the disease‘

Meanwhile, analysis of PCR positive swabs carried out on nearly 7,000 patients in the UK arm of Oxford’s trial suggests the vaccine may reduce transmission by 67 per cent.

29.01.2021 - 05:12 [ theGuardian.com ]

Why has Germany advised against Oxford/AstraZeneca jab for over-65s?

Prof Andy Pollard, of the University of Oxford, said the lack of data is understandable. “In our trials, the older adults were recruited later and, because they were recruited later there has been less time for cases to occur, and, older adults are known to be more cautious in the pandemic, meaning the ‘attack rate’ is lower,” he said.

AstraZeneca has stressed that older adults were recruited later because the team wanted to be sure the vaccine was safe before administering it to older age groups.

27.01.2021 - 01:34 [ theGuardian.com ]

Why experts say there is no basis to claims in Germany about efficacy of AstraZeneca vaccine

A University of Oxford spokesperson said clinical trials showed similar immune responses in younger and older adults, a good safety profile and high efficacy in younger adults. “There is no basis for the claims of very low efficacy of the Oxford/AstraZeneca vaccine which have been circulating in the media,” they said.

While it is true that there was less data from older adults involved in the trials, the team say early figures were promising: “Preliminary efficacy data in older adults supports the importance of this vaccine for use in this population,” they said.

21.01.2021 - 12:57 [ Radio Utopie ]

Denkt Boris Johnson mit?

Wir berichteten am 4. Dezember, dass der bereits im Frühjahr 2020 von der Oxford Universität entwickelte Impfstoff ChAdOx1 nCoV-19 (später AZD1222 oder Covishield) „jederzeit allen weiteren Varianten“ von SARS II angepasst werden kann. Wie der britische „Telegaph“ nun berichtet, geschieht dies jetzt.

Premierminister Boris Johnson, ansonsten umflutet von Myraden von Experten und sicherlich auch privat als Daddy gefordert, soll sich nun ausnahmsweise mit den Wissenschaftler.innen der Oxford Universität „intensiv“ unterhalten.

Es wurde auch Zeit.

21.01.2021 - 09:54 [ ORF.at ]

Bericht: AstraZeneca-Impfstoff wird überarbeitet

Wissenschaftlerinnen und Wissenschaftler der Universität Oxford überarbeiten den zusammen mit dem Konzern AstraZeneca entwickelten CoV-Impfstoff, damit dieser gezielt gegen die neuen, hochansteckenden Coronavirus-Mutationen eingesetzt werden kann, die in Großbritannien, Südafrika und Brasilien entdeckt wurden.

21.01.2021 - 09:45 [ Telegraph.co.uk ]

Oxford scientists preparing new vaccine versions to combat emerging Covid strains

A laboratory study found that the 501Y.V2 variant achieved „complete escape“ from monoclonal antibodies, the man-made proteins that act like the antibodies produced by jabs.

Boris Johnson said he was holding „intensive talks“ with scientists about the new variants. The Prime Minister told MPs he was confident that the Medicines and Healthcare products Regulatory Agency (MHRA) was capable of approving new vaccine modifications as quickly as necessary.

20.01.2021 - 12:15 [ BioProcessintl.com ]

AstraZeneca: ‘Manufacturing should take lion’s share of credit for vaccine success’

Back in March, Oxford University had “a limited manufacturing and supply capacity so they needed a partner,” Srinivasan said. “We decided to immediately offer our capacity in terms of the global reach. But that was only the beginning. Then we had to establish various alliances whether public partnerships that have been governments, or with for profit organizations or CMOs [some of which can be found here, here, and here], or not for profit organizations such as The Gates Alliance, GAVI, CEPI, and other organizations.”

16.01.2021 - 19:20 [ ABC News ]

India starts world’s largest COVID-19 vaccination drive

India on Jan. 4 approved emergency use of two vaccines, one developed by Oxford University and U.K.-based drugmaker AstraZeneca, and another by Indian company Bharat Biotech. Cargo planes flew 16.5 million shots to different Indian cities last week.

13.01.2021 - 17:57 [ theGuardian.com ]

How well does the Oxford vaccine work? What we know so far

(30.12.2020)

And while there are some early signs the Oxford/AstraZeneca vaccine might not only prevent people becoming seriously ill with Covid but also prevent asymptomatic infections, more data is needed to confirm such protection.

12.01.2021 - 14:35 [ Yahoo.com ]

China’s Kangtai starts mid-stage trial of its COVID-19 vaccine candidate

(29.10.2020)

Apart from developing its own vaccine, Kangtai also has a deal to make and supply mainland China with the vaccine candidate developed by AstraZeneca and researchers at the University of Oxford.

12.01.2021 - 14:20 [ LSE.co.uk ]

UPDATE 1-Brazil’s Fiocruz says AstraZeneca vaccine ingredients may be delayed weeks

(08.01.2021)

A source with knowledge of the situation said the active
ingredient is ready to be shipped to Brazil, but is still
waiting for an export license from China, where it is produced.

12.01.2021 - 14:15 [ theHill.com ]

AstraZeneca vaccine likely won’t be authorized in US until April

(30.12.2020)

The coronavirus vaccine developed by AstraZeneca and Oxford University is not likely to be authorized for use in the U.S. until April, a top Trump administration health official said Wednesday.

“We project, if everything goes well, that the readout and emergency use authorization may be granted somewhere early in the month of April,” Moncef Slaoui, the chief science adviser for the administration’s Operation Warp Speed, told reporters.

12.01.2021 - 13:08 [ Ben Mulcahy / Twitter ]

AstraZ did not apply for approval until now. EMA cannot approve what they do not get.

(…)

12.01.2021 - 13:01 [ Ursula von der Leyen, President of the @EU_Commission / Twitter ]

Good news! @AstraZeneca has applied to @EMA_News to have its vaccine authorised in the EU. @EMA_News will assess the vaccine’s safety & efficacy.

Once the vaccine receives a positive scientific opinion, we will work full speed to authorise its use in Europe.

12.01.2021 - 12:54 [ KleineZeitung.at ]

Zulassung beantragt: EU-Entscheidung über Astrazeneca-Vakzine folgt noch im Jänner

Für die EU und Österreich soll der ChAdOx1 nCoV-19-Impfstoff mit 400 Millionen vorbestellten Dosen das Rückgrat für die Durchimpfung der breiten Bevölkerung darstellen. Das wird auch dadurch erleichtert, dass die Vakzine bei normaler Kühlschranktemperatur von zwei bis acht Grad Celsius länger aufbewahrt werden kann.

10.01.2021 - 15:33 [ theGuardian.com ]

NHS could vaccinate UK against Covid in five days, says Oxford professor

Sir John Bell, regius chair of medicine at the University of Oxford, said stubborn NHS bureaucrats were standing in the way of a high-speed mass inoculation programme that could prevent many further deaths.

“The NHS has the theoretical capacity to immunise everybody in five days if they want to, but I don’t get the sense they are really motivated,” Bell told the Times.

06.01.2021 - 10:00 [ Ian Cornwell / Twitter ]

Ireland. Just had a 16 Billion Euro COVID bill, that it gets 1.5 back from. Waits patiently for the EMA to approve its vaccines. No sign of the EMA approving Oxford any time soon. 2009 – gets another Lisbon ref, whilst being threatened with perdition. „Independence“

06.01.2021 - 09:53 [ Giles Maybe / Twitter ]

EU land news. EMA who sign off vaccine has not even began to look at the AZ Oxford vaccine while its own curevac vaccine is still months away from approval. The eu failed to buy needles & its vaccine distributions hit a brick wall yesterday (accept holland They not yet started)

05.01.2021 - 08:22 [ Hindustan Times ]

Covid-19: UK begins immunisation drive of second vaccine, Mexico okays Oxford-AstraZeneca candidate

2. Mexico has approved the Oxford-AstraZeneca vaccine, its government announced on Monday, joining the UK, Argentina and India in giving a nod to the shot.

05.01.2021 - 08:19 [ NewsGhana.com.gh ]

Argentina and El Salvador approve AstraZeneca/Oxford Covid-vaccine

(31.12.2020)

Argentina has approved the coronavirus vaccine developed by Oxford University and the pharmaceutical company AstraZeneca, making it the second country after Britain to do so.

04.01.2021 - 17:17 [ Independent.co.uk ]

Matt Hancock blames Covid spread on public as government under pressure for new lockdown

Health secretary Matt Hancock has said that Boris Johnson’s tier system is “no longer strong enough” to deal with the new more virulent variant of coronavirus.

04.01.2021 - 07:37 [ DailyMail.co.uk ]

Operation Hope begins: Half a MILLION Covid-19 jabs will be made available to vulnerable people this week in UK’s biggest EVER mass vaccination drive as health bosses ramp up efforts to beat the pandemic

Elderly and infirm people in Oxford, London, Brighton, Morecambe in Lancashire and Nuneaton in Warwickshire are due to be first to receive the jab.

A total of 530,000 doses will be made available at 540 GP vaccination sites and 101 hospitals this week.

The NHS has ordered 100million doses which it is hoped will free the country from Covid-19.

04.01.2021 - 07:30 [ theSun.co.uk ]

First of 530,000 Oxford/AstraZeneca jabs to be rolled out today in Britain’s war on coronavirus

Hospitals at six NHS trusts across London, Brighton, Oxford, Morecambe and Nuneaton will be the first to give the vaccine.

It will reach more than 500 GP surgeries and community centres by the end of the week — with PM Boris Johnson saying “we are going as fast as we can”.

04.01.2021 - 07:28 [ theSun.co.uk ]

Amazing 7,750 volunteers sign up to The Sun’s Jabs Army appeal in first 48 hours

The Sun joined forces with the NHS and the Royal Voluntary Service to urge readers to volunteer as stewards at the pop-up vaccination centres across the UK. It launched on New Year’s Day.

According to the latest figures, 7,744 have signed up to help, with most of those crediting The Sun.

Catherine Johnstone CBE, chief exec of the Royal Voluntary Service, said: “The response from Sun readers has been incredible.

03.01.2021 - 08:08 [ Times of India ]

Global partnership COVAX secures two billion COVID-19 vaccine doses

(19.12.2020)

UNITED NATIONS: Global vaccine partnership COVAX has lined up almost two billion doses of existing and candidate COVID-19 vaccines for use worldwide, including 200 million doses of the AstraZeneca/Oxford vaccine through an agreement between the Vaccine Alliance Gavi, the Serum Institute of India and the Bill and Melinda Gates Foundation.

03.01.2021 - 06:56 [ DailyMail.co.uk ]

Boris Johnson hails Oxford vaccine as a ‚triumph for British science‘ and says he is ‚confident this is the year we will defeat coronavirus‘

The initial supplies of Oxford-AstraZeneca vaccine have been produced by a company called Halix in the Netherlands.

Once produced in bulk, the vaccine goes to a plant in Wrexham, run by an Indian company called Wockhardt, where it is decanted into vials in a process known as ‚fill and finish‘. The plant can bottle at least 150,000 doses a day.

02.01.2021 - 19:20 [ theSun.co.uk ]

First Oxford Covid vaccine doses arrive at UK hospitals with 530,000 jabs to be rolled out from Monday

While the Oxford vaccine uses a harmless, weakened version of a common virus in chimpanzees, the Pfizer jab is known as a messenger vaccine (MRNA), using a genetic code rather than a weakened form of the virus.

And experts have urged patients not to mix and match the two.

02.01.2021 - 19:11 [ ORF.at ]

EU-Kommissarin verteidigt Impfstrategie

Gleichzeitig habe man mit anderen Herstellern Verträge geschlossen. „Wir waren uns in der EU einig, dass wir nicht alles auf eine Karte setzen dürfen“, so die Kommissarin. Sonst wären die EU-Staaten womöglich ohne wirksamen Impfstoff dagestanden.

02.01.2021 - 19:06 [ DailyMail.co.uk ]

EU bureaucracy is accused of ‚costing lives‘ after European regulators said they cannot approve the Oxford vaccine before February

(31.12.2020)

Mr Wathion told Belgian newspaper Het Nieuwsblad the EMA was ‘in the dark’ about what kind of data was being used for Britain to approve the use of the Oxford vaccine.

The EU has already bought 400million doses of the jab while awaiting regulatory approval.

02.01.2021 - 14:59 [ news.com.au ]

Why no jab? Australia lags behind in race for vaccine

Despite assurances by Health Minister Greg Hunt that the progression of the vaccine was well under way, the Australian Government is unlikely to start immunising health workers and the elderly until at least March.

02.01.2021 - 14:56 [ SBS.com.au ]

AstraZeneca vaccine could get approval in Australia by late January

(31.12.2020)

The Australian government could grant final approval for the AstraZeneca/Oxford vaccine by late January, according to AstraZeneca Australia.

A spokesperson for the company told SBS World News that the federal government has indicated the vaccine could get final approval by January 31, with a roll out in March.

02.01.2021 - 08:32 [ .business-live.co.uk ]

Wrexham factory to produce millions of doses of the Oxford/AstraZeneca vaccine

(30.12.2020)

The Wrexham plant is able to produce around 300 million doses of the vaccine each year, and has been producing 150,000 phials a day for months in readiness to roll out the vaccine across the UK.

The CP Pharmaceuticals lab will carry out the „fill and finish“ stage of the manufacturing process. This involves dispensing the vaccine into vials ready for it to be sent out across the country.

The 18-month agreement with parent company Wockhardt was announced back in August.

02.01.2021 - 08:21 [ IndiaToday.in ]

Oxford Covid-19 vaccine Covishield gets emergency use approval in India

An expert panel on Covid-19 of the Central Drugs Standard Control Organisation (CDSCO) on Friday granted emergency use authorisation for the Oxford Covid-19 vaccine Covishield, being manufactured by Serum Institute of India, sources said on Friday.

01.01.2021 - 08:55 [ Radio Utopie ]

Wie die Briten mit der neuen Totalen Weltordnung brechen und die Aufhebung des Ausnahmezustands feiern könnten

Ich sage nicht, dass das passieren wird. Ich sage – sie könnten.

Stellt es Euch vor…

01.01.2021 - 08:50 [ Firstpost.com ]

EU still holds out on granting approval to Oxford-AstraZeneca’s COVID-19 vaccine

„Additional scientific information on issues related to quality, safety and efficacy of the vaccine is deemed necessary to support the rigour required for a conditional marketing authorisation (CMA) and this has been requested from the company,“ the EMA said in a statement. „Further information from the ongoing clinical trials is also expected from January.“

The Amsterdam-based agency earlier told AFP that it had not yet received any formal marketing authorisation and that it had set no timetable for approving the vaccine.

31.12.2020 - 06:48 [ DailyMail.co.uk ]

PROFESSOR ANGUS DALGLEISH: The Oxford AstraZeneca coronavirus vaccine is as close to a miracle as medicine ever gets

Everyone can see what a serious emergency this is. We have to act. Bin the bureaucracy, and get this miracle vaccine to work right now.

31.12.2020 - 05:26 [ theGuardian.com ]

How well does the Oxford vaccine work? What we know so far

And while there are some early signs the Oxford/AstraZeneca vaccine might not only prevent people becoming seriously ill with Covid but also prevent asymptomatic infections, more data is needed to confirm such protection.

30.12.2020 - 17:39 [ New York Times ]

U.K. Authorizes Covid-19 Vaccine From Oxford and AstraZeneca

A decision is further off in the United States, where the Food and Drug Administration is waiting for data from a separate clinical trial. The study was halted in September and delayed for nearly seven weeks — much longer than in other countries — as regulators investigated whether an illness in a participant in Britain was related to the vaccine. American regulators ultimately allowed the trial to proceed.

30.12.2020 - 16:16 [ Boris Johnson, Prime Minister of the United Kingdom / Twitter ]

It is truly fantastic news – and a triumph for British science – that the @UniofOxford /@AstraZeneca vaccine has been approved for use. We will now move to vaccinate as many people as quickly as possible.

30.12.2020 - 12:24 [ AstraZeneca.com ]

AstraZeneca and Oxford University announce landmark agreement for COVID-19 vaccine

(30.04.2020)

The collaboration aims to bring to patients the potential vaccine known as ChAdOx1 nCoV-19, being developed by the Jenner Institute and Oxford Vaccine Group, at the University of Oxford. Under the agreement, AstraZeneca would be responsible for development and worldwide manufacturing and distribution of the vaccine.

30.12.2020 - 12:14 [ thehindubusinessline.com ]

AstraZeneca’s Covid-19 vaccine may have to wait for EU’s approval

The EMA’s deputy executive director Noel Wathion told Belgian newspaper Het Nieuwsblad that the pharmaceutical company “has not even filed an application” with the European drug regulators yet.

He further said that EMA “did not even have enough to warrant a conditional marketing license.”

30.12.2020 - 11:55 [ ntv Nachrichten / Twitter ]

Wohl keine Zulassung im Januar: EMA: Astrazeneca hat noch nichts beantragt

30.12.2020 - 11:06 [ ABC.net.au ]

Australia locks in coronavirus vaccine deal to produce Oxford University-AstraZeneca candidate if approved

(18 August 2020)

Amid rising pressure to lock in supply of a coronavirus vaccine, the Government has signed an agreement with UK-based drug company AstraZeneca to secure the potential COVID-19 vaccine developed by Oxford University, if its trials prove successful.

30.12.2020 - 11:00 [ Sydney Morning Herald ]

AstraZeneca/Oxford COVID-19 vaccine approved in Britain

Australia has secured 53.8 million doses of the Oxford vaccine, most of which could be manufactured locally by CSL. The federal government has also ordered 10 million doses of the Pfizer vaccine, which will all have to be imported.

Federal Health Minister Greg Hunt said on Monday he expects Australia to be „fully vaccinated“ against coronavirus by October next year.

30.12.2020 - 10:53 [ zeenews.india.com ]

COVID-19: UK approves use of AstraZeneca-Oxford vaccine, all eyes on India now

The approval by UK government is a good news for India because as per sources, the government was waiting for this approval and it is expected that Indian regulators would call SEC meet soon and reconsider the data and approve AstraZeneca vaccine for its use in India.

30.12.2020 - 10:09 [ UK Department of Health and Social Care / UK Medicines and Healthcare Products Regulatory Agency ]

Oxford University/AstraZeneca vaccine authorised by UK medicines regulator

The Government has today accepted the recommendation from the Medicines and Healthcare products Regulatory Agency (MHRA) to authorise Oxford University/AstraZeneca’s Covid-19 vaccine for use.

30.12.2020 - 10:05 [ BBC ]

Covid-19: Oxford-AstraZeneca coronavirus vaccine approved for use in UK

The Oxford-AstraZeneca vaccine has been approved for use in the UK, with the first doses due to be given on Monday amid rising coronavirus cases.

30.12.2020 - 03:58 [ mark cording / Twitter ]

What’s the update on the Oxford vaccine Mr Hancock

30.12.2020 - 03:50 [ Matt Hancock, secretary of State for Health & Social Care / Twitter ]

Fantastic to see Margaret Keenan receive her second dose of the @Pfizer /@BioNTech_Group #coronavirus vaccine

30.12.2020 - 03:38 [ BBC ]

Covid: Millions more braced for tougher rules in England

Government sources have indicated an announcement later will see more areas move into tier four – „stay at home“.

Health Secretary Matt Hancock is due to detail the changes – which could be introduced within days – in the House of Commons after 14:30 GMT.

30.12.2020 - 03:35 [ noone@nowhere / Twitter ]

Still no Oxford vaccine emergency approval. Unbelievable.

(23.12.2020)

28.12.2020 - 17:26 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

28.12.2020 - 17:25 [ Telegraph.co.uk ]

Coronavirus latest news: One million vaccinations a week will not bring pandemic under control, warns Sage expert

Sir Jeremy Farrar, the director of the Wellcome Trust who advises Number 10’s advisory panel Scientific Advisory Group for Emergencies (Sage) said: „We’re not going to be free of this pandemic by February, this is now a human endemic infection.

28.12.2020 - 17:24 [ .oxfordmail.co.uk ]

No herd immunity through vaccine programme before summer, Sage scientist warns

Calum Semple, professor of outbreak medicine at the University of Liverpool and a member of the Scientific Advisory Group for Emergencies (Sage), described the Oxford/AstraZeneca vaccine as a “game changer” if it is approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the coming days.

But he told BBC Breakfast…

28.12.2020 - 09:24 [ Telegraph.co.uk ]

Oxford coronavirus vaccine: 10,000 medics and volunteers recruited to administer jab

The Oxford/AstraZeneca jab could be approved early next week by the independent Medicines and Healthcare products Regulatory Agency (MHRA), after the final cut of data was submitted by the Government last Monday.

28.12.2020 - 05:18 [ noone@nowhere / Twitter ]

Still no Oxford vaccine emergency approval. Unbelievable.

(23.12.2020)

27.12.2020 - 11:09 [ DailyMail.co.uk ]

Britain could be free of Covid restrictions by February after ministers pinpointed the 15million people to vaccinate to end the cycle of lockdowns, with Oxford’s jab due to be approved Monday and rolled out within a week

Government sources say that between 12 million and 15 million people have been identified as likely to require hospital treatment if they contract coronavirus, or be at risk of dying from it. Once this group has received the vaccine – which some officials hope could be achieved by the end of February – then the NHS would no longer be at risk of being overwhelmed if the virus spread through the greater population. That would remove the main argument for shutting the economy at a stroke.

A source said: ‚The path to liberation is finally becoming clear.‘

27.12.2020 - 11:02 [ theSun.co.uk ]

‚THE BEST OF BRITISH‘: Oxford Covid vaccine expected to be approved MONDAY as huge efforts ‘pay off’

„We have seen the best of British at every stage, from our world-leading scientists working around the clock to carry out vital research, to builders and engineers constructing new facilities.

“Manufacturers are boosting their capabilities and hundreds of thousands of people in every corner of the UK are taking part in clinical trials ­­— developing, finding and preparing for a vaccine has involved us all.

“It has and continues to be a truly UK-wide effort and one which showcases what a fantastic nation we are.”

27.12.2020 - 05:22 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

27.12.2020 - 05:20 [ Sean / Twitter ]

Can I ask why the Oxford vaccine approval is taking so long? It only took 23 days for Pfizers, we are nearly at day 30 and still no sign of approval!

(21.12.2020)

27.12.2020 - 05:05 [ Telegraph.co.uk ]

Millions to receive Oxford coronavirus vaccine from Jan 4

The Government is aiming for two million people to receive their first dose of either the Oxford vaccine or the Pfizer jab within a fortnight as part of a major ramping up of the inoculation programme.

23.12.2020 - 11:32 [ BBC ]

Oxford vaccine: How did they make it so quickly?

(23.11.2020)

Scientists took a common cold virus that infected chimpanzees and engineered it to become the building block of a vaccine against almost anything.

Before Covid, 330 people had been given ChAdOx1 based-vaccines for diseases ranging from flu to Zika virus, and prostate cancer to the tropical disease chikungunya.

The virus from chimps is genetically modified so it cannot cause an infection in people. It can then be modified again to contain the genetic blueprints for whatever you want to train the immune system to attack.

23.12.2020 - 11:18 [ inews.co.uk ]

Boris Johnson’s future as Prime Minister rests on the Oxford vaccine being approved

The hope in Downing Street is that the Oxford vaccine will get the green light by the end of the year. This would allow the Prime Minister to start laying out plans for restrictions to be lifted.

23.12.2020 - 11:13 [ Times of India ]

India likely to approve AstraZeneca vaccine by next week

India is likely to approve Oxford/AstraZeneca’s coronavirus vaccine for emergency use by next week after its local manufacturer submitted additional data sought by authorities, two sources with knowledge of the matter told Reuters on Tuesday.

21.12.2020 - 22:37 [ DailyMail.co.uk ]

UK has vaccinated 500,000 people against Covid since December 8, Boris Johnson says as regulators face growing pressure to approve Oxford’s jab in desperate race to speed up the roll-out

The MHRA drugs regulator has been doing its final review of the vaccine for three weeks now, since November 27, with a decision expected by next Tuesday.

(…)

However, they made a decision about Pfizer and BioNTech’s jab within 10 days of being instructed to do so by the Department of Health.

21.12.2020 - 22:35 [ New York Times ]

How the Oxford-AstraZeneca Vaccine Works

The Oxford-AstraZeneca team used a modified version of a chimpanzee adenovirus, known as ChAdOx1. It can enter cells, but it can’t replicate inside them. (…)

The Oxford-AstraZeneca vaccine for Covid-19 is more rugged than the mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. As a result, the Oxford vaccine doesn’t have to stay frozen.

20.12.2020 - 10:10 [ theGuardian.com ]

Oxford vaccine still under review, says UK medicine agency

But Whitehall sources said that while they hoped the vaccine would be available that week, it was by no means certain, and the authorisation could be delayed until the beginning of January.

The delay has caused frustration in Whitehall and the NHS, with the vaccine taking much longer to meet approval than the Pfizer vaccine, which was rolled out in the UK last week.

12.12.2020 - 20:01 [ NBC News ]

Scientist behind Oxford vaccine urges FDA not to delay data review

Professor Adrian Hill, part of the team behind the Oxford-AstraZeneca Covid-19 vaccine, says he hopes the FDA will review the available data in January, because waiting for the trial’s end next year would be “too late.”

12.12.2020 - 20:00 [ CNN ]

It took AstraZeneca researchers 1 month to get vaccine trial data to FDA, source tells CNN

(14.10.2020)

The source said the root of the delay is that the participant was in the United Kingdom, and the European Medicines Agency and the FDA store data differently.

„They had to convert data from one format to another format. It’s like taking stuff off a PC and putting it onto an Apple. They had to spend a lot of hours to get what they wanted,“ the source said.

12.12.2020 - 19:43 [ New York Times ]

Blunders Eroded U.S. Confidence in Early Vaccine Front-Runner

AstraZeneca was in part to blame for the delay, said the people with knowledge of the F.D.A. talks. The company was slow to provide the F.D.A. with all the data that regulators wanted to review before allowing the trial to start up again.

In late October, after 47 days, the F.D.A. cleared the U.S. trial to restart.

It was now even further behind the late-stage trials that Pfizer and Moderna had begun in the United States about a month before AstraZeneca’s trial started.

09.12.2020 - 20:31 [ Standard.co.uk ]

How does Oxford University’s coronavirus vaccine work and how is it different to Pfizer and Moderna’s?

Does it differ to PFizer and Moderna’s vaccines?

Yes. The jabs from Pfizer and Moderna are messenger RNA (mRNA) vaccines.

Conventional vaccines are produced using weakened forms of the virus, but mRNAs use only the virus’s genetic code.

08.12.2020 - 18:13 [ University of Oxford ]

First peer-reviewed results of phase 3 human trials of Oxford coronavirus vaccine demonstrate efficacy

. These data indicate that the low dose / standard dose vaccine may provide a protection against asymptomatic infection, but stress that these data are at an early phase, with too high a level of uncertainty to be certain that this vaccine will protect against asymptomatic infection.

08.12.2020 - 18:12 [ theLancet.com ]

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

ChAdOx1 nCoV-19 appears to be better tolerated in older adults than in younger adults and has similar immunogenicity across all age groups after a boost dose.

08.12.2020 - 18:11 [ DailyMail.co.uk ]

Oxford confirms its Covid vaccine is 70% effective and safe – but scientists warn regulators face ‚dilemma‘ in approving jab to be given as 1.5 doses (which they accidentally found is 90% protective)

The MHRA has been considering whether to approve the vaccine since November 27 and is expected to reach a decision before the end of the year.

03.12.2020 - 19:58 [ FT.com ]

Oxford vaccine professor Sarah Gilbert on working as the world watches

Sarah Gilbert was at home at the start of the year when she received her first inkling of the perplexing new disease that within months would make her one of the best-known scientists on the planet………..

02.12.2020 - 15:25 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

(23.11.2020)

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

02.12.2020 - 15:19 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

01.12.2020 - 12:19 [ fiercepharma.com ]

AstraZeneca CEO blames trial delays, not manufacturing, for COVID-19 vaccine delivery shortfall

In fact, AZ has already produced a bulk vaccine that’s kept at freezing temperatures.

01.12.2020 - 12:12 [ Yahoo.com ]

Delivery timetable for Oxford/AstraZeneca vaccine slips, UK official says

UK Vaccine Taskforce Chair Kate Bingham said that the vaccine was being made in bulk first, known as „drug substance“, but could not yet be put into vials until more was known on the timing of late-stage trial data.

„We’ve not yet put them into vials because as soon as you put them into vials you start the clock for the… shelf life, or how quickly you have to use the vaccine,“ she told lawmakers.

23.11.2020 - 17:15 [ DailyMail.co.uk ]

‚I’m so thrilled that you’ve cracked it!‘: Prince William congratulates Oxford scientists via Zoom as their Covid vaccine is proved to be 90 per cent effective

– The Duke of Cambridge hailed the team’s ‚amazing achievement‘ this morning
– Three Oxford professors told how the vaccine is based on decades of research
– It emerged this month that William caught coronavirus in April but didn’t reveal it

23.11.2020 - 17:11 [ Politico.com ]

AstraZeneca to seek FDA authorization for vaccine based on foreign trial data

The company halted its U.S. trial in early September over safety concerns, after a trial participant reported neurological problems. The study resumed earlier this month after FDA concluded that no evidence linked the volunteer’s symptoms to the shot.

23.11.2020 - 17:04 [ Telegraph.co.uk ]

AstraZeneca shares slip after analyst says vaccine will struggle to get green light in US – live updates

SVB Leerink analyst Geoffrey Porges said the treatment may never gain approval from US regulator the FDA, and said Astra had highlighted results from a “relatively small” number of patients.

23.11.2020 - 16:40 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

23.11.2020 - 16:23 [ Tagesschau.de ]

Studienergebnisse von AstraZeneca: Britischer Impfstoff wirkt zu 70 Prozent

Das Ergebnis bleibt zwar hinter den Werten der Präparate von Pfizer/Biontech und Moderna zurück. Wenn man aber zunächst nur eine halbe Dosis verabreiche und erst einen Monat später eine volle, dann erreiche der Impfstoff eine Effektivität von 90 Prozent, lässt AstraZeneca wissen. Er soll zudem deutlich preiswerter sein, sich sehr viel leichter lagern und weltweit transportieren lassen als andere Vakzine.

23.11.2020 - 16:15 [ University of Oxford ]

Oxford University breakthrough on global COVID-19 vaccine

he University of Oxford, in collaboration with AstraZeneca plc, today announces interim trial data from its Phase III trials that show its candidate coronavirus vaccine, ChAdOx1 nCoV-2019, is effective at preventing COVID-19 (SARS-CoV-2) and offers a high level of protection.

16.11.2020 - 13:40 [ ChronicleLive.co.uk ]

UK’s Covid-19 Oxford AstraZeneca vaccine on course to be ready by end of 2020

The UK has ordered 100 million doses of the Oxford AstraZeneca vaccine – enough for the entire population

12.11.2020 - 11:12 [ HeraldScotland.com ]

Top Scots academic warns ministers not to prioritise Pfizer vaccine

The vaccine, which is thought to be effective against Covid-19 in nine out of 10 people, could be ready for distribution by next month but it needs to be stored at -80C for it to work.

This ‚ultra-cold‘ state is part of the logistical challenge facing the country, particularly if the vaccine is manufactured overseas.

The professor, from the university’s Centre for Sustainable Road Freight, explained that it may make more sense to prioritise the AstraZenica Oxford vaccine which can be made in the UK.

12.11.2020 - 11:09 [ Mark Sanders / Twitter ]

So the Pfizer vaccine is expected to be up to seven times more expensive than the Oxford one, reports the Times.

Welcome to profit first, morals later America.

12.11.2020 - 11:01 [ eastdevonwatch.org ]

Oxford v Pfizer: how costs and logistics could still see Oxford’s vaccine win out

Matt Hancock has warned the mass distribution would be a “colossal exercise” involving not just the NHS but the Armed Forces.

The Health Secretary acknowledged there was “enormous complexity” in administering the Pfizer vaccine.

10.11.2020 - 17:39 [ Brian / Twitter ]

Oxford vaccine is not mRNA based its DNA based. This is prolly the best description right now:

10.11.2020 - 17:36 [ Keir Shiels / Twitter ]

This vaccine needs to be kept at below -80 ^C because it uses mRNA. Not suitable for most clinics and GP practices. My money is still on Oxford to produce a more effective and ergonomic one.

09.11.2020 - 18:27 [ timesnownews.com ]

Oxford-AstraZeneca COVID-19 vaccine production begins in Australia

The Sydney Morning Herald reported that it will take CSL about 50 days to completely process the vaccine. According to the newspaper, the company has separate contracts with AstraZeneca and the Australian government for the production of the vaccine.

The AstraZeneca vaccine still needs to be approved by Australia’s Therapeutic Goods Administration (TGA). Phase three clinical trials of the vaccine are expected to wrap up by the end of this year.

08.11.2020 - 19:43 [ DailyMail.co.uk ]

The tube that could change the world: First vial of COVID-19 vaccine ’starting material‘ after Australian breakthrough – with millions to be made from tomorrow

Biotechnology giant CSL announced they would start producing the AstraZeneca AZD1222 coronavirus vaccine at its factory in Melbourne this week.

About 30million doses will be manufactured as part of a first-of-its-kind agreement with the Australian government, with the company hoping to release them in the first half of 2021 pending clinical trials and approval.

The jab, which was produced at the University of Oxford, is seen as the leading candidate across the globe and is in final-stage trials.

07.11.2020 - 14:53 [ University of Oxford ]

The Oxford Vaccine

The University of Oxford’s Jenner Institute and Oxford Vaccine Group have been at the forefront of scientific endeavour to develop vaccines for diseases of major global importance for more than 30 years.

Their ChAdOx1 trials are currently assessing whether the vaccine will be effective in combatting COVID-19.

07.11.2020 - 14:30 [ Indiatoday.in ]

Coronavirus Vaccine Update: India shifts focus on indigenous vaccine as AstraZeneca deliveries run late

India seems to have shifted focus on its indigenous novel coronavirus vaccine soon after AstraZeneca said earlier this week that it was holding back deliveries of its Covid-19 vaccine.

07.11.2020 - 14:26 [ Boris Johnson, Prime Minister of the United Kingdom / Twitter ]

Thank you to all of our brilliant scientists at @UniOfOxford , @AstraZeneca & across the UK who are working tirelessly to find a vaccine and to all those who have volunteered to take part in a clinical trial. This government – and the whole country – are backing you 100%

(06.11.2020)

07.11.2020 - 14:21 [ Reuters ]

COVID vaccine deliveries on ice as AstraZeneca awaits trial data

(05.11.2020)

A summer dip in UK coronavirus infections has pushed back test results for AstraZenca’s potential COVID-19 vaccine, leading the drugmaker to delay deliveries of shots to the UK government.

03.11.2020 - 14:59 [ DailyMail.co.uk ]

More proof England’s lockdown was premature? Top researchers say R rate has dropped to 1 as Oxford expert claims Covid infections are ‚flatlining‘ and the ‚4,000 deaths‘ graph used to justify restrictions has ‚proven to be incorrect‘

– King’s College London said cases were now ‚plateauing‘ and there was a ’slight fall‘ in infections across UK
– Oxford’s Carl Heneghan said told how coronavirus hospital admissions, cases and ‚in effect‘ deaths in retreat
– It comes as Sir Patrick Vallance and Prof Chris Whitty face questions from MPs over the 4,000 deaths figure

02.11.2020 - 15:38 [ DailyMail.co.uk ]

How Vallance’s secret blood-curdling press briefing on looming lockdown – an hour BEFORE Boris agreed to it – lit the fuse on Nov 5th shutdown that could blow up our economy

– Boris Johnson announced England-wide lockdown after weeks insisting he would stick to his local ‚Tiers‘
– The PM summoned a dramatic press conference Saturday night after details of the U-turn idea were leaked
– Sir Patrick Vallance gave blood-curdling briefing about the situation on Friday before ministers made decision
– More details were then leaked overnight before the wider Cabinet had been gathered, forcing the PM’s hand
Mr Johnson is set to use a statement to the House of Commons this afternoon to say there is ’no alternative‘

02.11.2020 - 15:33 [ DailyMail.co.uk ]

Apocalyptic forecast of 4,000 coronavirus deaths a day could be FIVE TIMES too high and had already been proved wrong when government revealed it at weekend

– Sir Patrick Vallance presented worst-case scenario in Saturday’s briefing when lockdown was confirmed
– But it has emerged it was based on forecasts made weeks ago and since updated to give lower estimates
– Oxford’s Carl Heneghan said he was ‚concerned‘ at officials‘ choice to use old data which could be misleading
– Tory MPs accused SAGE, of which Vallance is chair, of ‚cherry-picking‘ figures and not giving full picture
– England will be thrust into a second lockdown from Thursday, pending a vote in Parliament on Wednesday

01.11.2020 - 18:09 [ Reuters Canada ]

Britain starts accelerated review for AstraZeneca’s potential COVID-19 vaccine

Work began on the Oxford vaccine in January. Called AZD1222 or ChAdOx1 nCoV-19, the viral vector vaccine is made from a weakened version of a common cold virus that causes infections in chimpanzees.

30.10.2020 - 13:20 [ DailyMail.co.uk ]

German Pfizer vaccine could be ready before Oxford-AstraZeneca injection and be given to Brits before Christmas

Ms Bingham was appointed chair of the UK’s Vaccine Taskforce for Covid-19 in May and reports directly to the Prime Minister on the progress of a coronavirus vaccine, which experts say is key to controlling the pandemic.

The taskforce, which Ms Bingham says was the ‚brainchild of Sir Patrick Vallance‘ — Number 10’s chief scientific adviser, is at the forefront of putting plans in place to get the UK population vaccinated.

30.10.2020 - 12:50 [ Cleveland.com ]

University Hospitals and CWRU join global study of AstraZeneca’s COVID-19 vaccine

AstraZeneca paused its trial in early September to review safety data because a British trial participant developed a neurological condition.

Last week, the Food and Drug Administration authorized the resumption of the company’s U.S. trials after reviewing global safety data. The trial had already resumed in other countries.

30.10.2020 - 12:46 [ tipranks.com ]

Astrazeneca Scores $286.9M US Army Contract For Covid Vaccine

Astrazeneca Pharmaceuticals (AZN) has been awarded a $286.9 milllion firm-fixed-price contract for the delivery of 200 million doses of AZD1222 vaccine for COVID- 19.

Bids were solicited via the internet with one received, the US Department of Defense revealed.

29.10.2020 - 05:51 [ marketscreener.com ]

EU warns not enough COVID vaccines for all in Europe until 2022

(27.10.2020)

The EU has so far secured doses of the potential vaccines being developed by AstraZeneca, Sanofi and Johnson & Johnson. It has also said it is in talks with …

29.10.2020 - 05:48 [ Times of Israel ]

Germany to include Israel in EU deal for vaccine, citing ‘special relationship’

(14.10.2020)

Berlin’s foreign minister reportedly tells Gabi Ashkenazi that Israel will get AstraZeneca COVID-19 inoculation when it is sold to European countries

29.10.2020 - 05:43 [ Zara / Twitter ]

European Commission say that AstraZeneca has sold its jab at about $3 to $4 a dose in deals with the EU

29.10.2020 - 05:31 [ Bloomberg ]

Astra-Oxford Vaccine Stays Near Front of Line Despite U.S. Delay

A seven-week halt to a U.S. trial of the Covid vaccine developed by AstraZeneca Plc and the University of Oxford bumped it from pole position in the race for a protective shot, but it’s still in the leading pack.

26.10.2020 - 17:20 [ CNBC ]

AstraZeneca says its coronavirus vaccine triggers immune response among adults

“It is encouraging to see immunogenicity responses were similar between older and younger adults and that reactogenicity was lower in older adults, where the COVID-19 disease severity is higher,” an AstraZeneca spokesman told CNBC via email.

“The results further build the body of evidence for the safety and immunogenicity of AZD1222,” the spokesman said, referring to the technical name of the Oxford-AstraZeneca vaccine.

26.10.2020 - 17:19 [ CNN ]

It took AstraZeneca researchers 1 month to get vaccine trial data to FDA, source tells CNN

(14.10.2020)

The source said the root of the delay is that the participant was in the United Kingdom, and the European Medicines Agency and the FDA store data differently.

„They had to convert data from one format to another format. It’s like taking stuff off a PC and putting it onto an Apple. They had to spend a lot of hours to get what they wanted,“ the source said.

26.10.2020 - 17:17 [ Statnews.com ]

As AstraZeneca’s Covid-19 vaccine trial remains on hold in U.S., participants waiting on a second dose are in limbo

(06.10.2020)

Still, such participants occupy an unusual position in a trial shutdown that is being closely watched as a potential indicator of the prospects of a frontrunner in the race to develop a vaccine to curb the devastation of the Covid-19 pandemic.

For the participant who spoke with STAT — and others in his same position who can’t currently get their booster shot — the trial halt has become a waiting game. “Now, we’re waiting as the lab rats in the corner,” said the participant, who requested anonymity because he was worried he could face consequences if study investigators found out he had spoken to the press.

23.10.2020 - 11:34 [ University of Bristol ]

Oxford COVID-19 vaccine follows its programmed genetic instructions, independent analysis finds

The AstraZeneca Oxford COVID-19 vaccine (ChAdOx1 nCoV-19 and also known as AZD1222) now undergoing Phase III clinical trials, has already undergone rigorous testing to ensure the highest standards of quality and safety. Now a team at Bristol University has used recently developed techniques to further validate that the vaccine accurately follows the genetic instructions programmed into it by the Oxford team. This novel analysis provides even greater clarity and detail about how the vaccine successfully provokes a strong immune response.

20.07.2020 - 17:39 [ Bloomberg ]

U.K. Orders 90 Million Vaccine Doses from Pfizer and Valneva

“It’s the right thing to be doing to be at the absolute front of the queue to make sure we’re in a position to get those vaccines first when they become available,” Education Secretary Gavin Williamson told the BBC during the government’s media round on Monday.

20.07.2020 - 17:31 [ Telegraph.co.uk ]

Oxford coronavirus vaccine is safe and induces immune reaction, findings suggest

Initial trials on 1,077 British adults found that the vaccine induced strong antibody and T-cell responses, which may improve further after a booster jab, as reported by the Telegraph.

There were found to be no serious adverse events, and minor side effects could be controlled by paracetamol, two papers in The Lancet reported.

10.05.2020 - 06:26 [ Medrxiv.org ]

Fundamental principles of epidemic spread highlight the immediate need forlarge-scale serological surveys to assess the stage of the SARS-CoV-2 epidemic

(26.03.2020)

Three different scenarios under which the model closely reproduces the reported death counts in the UK up to 19/03/2020​ are presented in ​Figure 1​. Red and green colours represent solutions attached respectively to transmission scenarios with R​0​=2.75 and R​0​=2.25 (reflecting variation in estimates of R​0in literature) with the proportion of the population at risk being distributed around 1%.

10.05.2020 - 06:20 [ Ooxfordstudent.com ]

The Oxford study on Covid-19 could be too good to be true…

(29.03.2020)

Overall, the researchers conclude an infection rate of between 36-68% among the UK population before 19 March. This percentile range is unquestionably large, but we must remember that this is an early model with quite limited data. The study itself says that 36-40% of the population could have been infected if the mortality rate was 1%.