03.04.2020 - 10:35 [ Kai Kupferschmidt / threadreaderapp.com ]

My good news contribution for today: Researchers in Denmark are starting to test a promising drug in #covid19 patients, barely a month after research appeared showing the drug could stop the virus in cell culture.

KroganLab Camostat mesylate binds to a protein on human cells called TMPRSS2. And SARS-CoV-2 needs this protein to efficiently enter human cells: The spike protein on top of the virus attaches to the ACE2 receptor on human cells. And then TMPRSS2 needs to make a cut in the spike.