26.03.2020 - 08:35 [ Deutsches Primatenzentrum - Leibniz-Institut für Primatenforschung ]

Preventing spread of SARS coronavirus-2 in humans: Göttingen infection researchers identify potential drug

(05.03.2020)

Since it is known that the drug camostat mesilate inhibits the protease TMPRSS2, the researchers have investigated whether it can also prevent infection with SARS-CoV-2. „We have tested SARS-CoV-2 isolated from a patient and found that camostat mesilate blocks entry of the virus into lung cells,“ says Markus Hoffmann, the lead author of the study. Camostat mesilate is a drug approved in Japan for use in pancreatic inflammation. „Our results suggest that camostat mesilate might also protect against COVID-19,“ says Markus Hoffmann. „This should be investigated in clinical trials.“