Archiv: studies


08.02.2021 - 16:34 [ Reuters ]

New COVID-19 variant defeats plasma treatment, may reduce vaccine efficacy

(20.01.2021)

“This lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies,” the team of scientists from three South African universities working with the National Institute for Communicable Diseases (NICD) wrote in a paper in bioRxiv, a website that publishes scientific research prior to its being peer-reviewed and submitted to journals.

08.02.2021 - 16:22 [ DailyMail.co.uk ]

AstraZeneca is working on Covid vaccine booster ‚that will be ready by autumn‘ to beat South African strain after research showed its current version had ‚minimal‘ effect on stopping it

Professor Gilbert earlier told the BBC’s Andrew Marr Show that her team currently has ‚a version with the South African spike sequence in the works‘ with hopes it will be ready to administer by the autumn.

‚It’s not quite ready to vaccinate people with yet, but, as all of the developers are using platform technologies, these are ways of making a vaccine that are very quick to adapt,‘ she added.

08.02.2021 - 16:16 [ DailyMaverick.co.za ]

South Africa switches to J&J’s ‘silver bullet’ as AstraZeneca vaccine falters against local variant of coronavirus

“Unfortunately, viruses mutate. Sometimes this is by accident. But often the reason is that the virus wants to become more adept to infect the host.”

This, Madhi explained, was what had happened with the South African variant as well as another variant that was first identified in the United Kingdom.

07.02.2021 - 15:40 [ University of Oxford ]

Oxford coronavirus vaccine shows sustained protection of 76% during the 3-month interval until the second dose

(02.02.2021)

The authors also report further on the potential for the vaccine to reduce transmission of the virus, based on swabs obtained from volunteers in the UK arms of the trial with a 67% reduction after the first dose of the vaccine.

02.02.2021 - 23:55 [ Social Science Research Network ]

Single dose administration, and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine

If there was no impact of a vaccine on asymptomatic infection, it would be expected that an efficacious vaccine would simply convert severe cases to mild cases and mild cases to asymptomatic, with overall PCR positivity unchanged. A measure of overall PCR positivity is appropriate to assess whether there is a reduction in the burden of infection. Analyses presented here show that a single standard dose of the vaccine reduced PCR positivity by 67%, and that, after the second dose, the SD/SD schedule reduced PCR positivity by 49.5% overall. These data indicate that ChAdOx1 nCoV-19, used in the authorised schedules, may have a substantial impact on transmission by reducing the number of infected individuals in the population.

02.02.2021 - 23:55 [ DailyMail.co.uk ]

Single shot of Oxford University’s Covid jab ‚is 76% effective for 12 weeks and may block seven in 10 people from spreading the disease‘

Meanwhile, analysis of PCR positive swabs carried out on nearly 7,000 patients in the UK arm of Oxford’s trial suggests the vaccine may reduce transmission by 67 per cent.

17.01.2021 - 19:52 [ Newsweek ]

COVID Lockdowns May Have No Clear Benefit vs Other Voluntary Measures, International Study Shows

(14.01.2021)

The peer reviewed study was published in the European Journal of Clinical Investigation on January 5, and analyzed coronavirus case growth in 10 countries in early 2020.

The study compared cases in England, France, Germany, Iran, Italy, Netherlands, Spain and the U.S. – all countries that implemented mandatory lockdown orders and business closures – to South Korea and Sweden, which instituted less severe, voluntary responses. It aimed to analyze the effect that less restrictive or more restrictive measures had on changing individual behavior and curbing the transmission of the virus.

14.01.2021 - 12:17 [ Stanford University / Wiley Online Library ]

ASSESSING MANDATORY STAY-AT-HOME AND BUSINESS CLOSURE EFFECTS ON THE SPREAD OF COVID-19

(released 05.01.2021)

Conclusions: While small benefits cannot be excluded, we do not find significant benefits on case growth of more restrictive NPIs. Similar reductions in case growth may be achievable with less restrictive interventions.

14.01.2021 - 12:06 [ Zero Hedge ]

Lockdowns Do Not Control The Coronavirus: The Evidence

(21.12.2020)

Much of the following list has been put together by data engineer Ivor Cummins, who has waged a year-long educational effort to upend intellectual support for lockdowns. AIER has added its own and the summaries. The upshot is that the virus is going to do as viruses do, same as always in the history of infectious disease. We have extremely limited control over them, and that which we do have is bound up with time and place. Fear, panic, and coercion are not ideal strategies for managing viruses. Intelligence and medical therapeutics fare much better.

(These studies are focused only on lockdown and their relationship to virus control. They do not get into the myriad associated issues that have vexed the world such as mask mandates, PCR-testing issues, death misclassification problem, or any particular issues associated with travel restrictions, restaurant closures, and hundreds of other particulars about which whole libraries will be written in the future.)

11.01.2021 - 20:39 [ University of Cambridge / Phys.org ]

Study identifies genetic changes likely to have enabled SARS-CoV-2 to jump from bats to humans

A new study, involving the University of Cambridge and led by the Pirbright Institute, has identified key genetic changes in SARS-CoV-2—the virus that causes COVID-19—that may be responsible for the jump from bats to humans, and established which animals have cellular receptors that allow the virus to enter their cells most effectively.

The genetic adaptions identified were similar to those made by SARS-CoV—which caused the 2002-2003 SARS epidemic—when it adapted from bats to infect humans.

21.12.2020 - 21:45 [ BJG, Former National Press Secretary for #BernieSanders2020 / Twitter ]

Why don’t elected Democrats support a bill that nearly 90% of Democratic voters support? #ForceTheVote

21.12.2020 - 21:41 [ Jacobin Magazine ]

A New Congressional Budget Office Study Shows That Medicare for All Would Save Hundreds of Billions of Dollars Annually

The most exhaustive study on Medicare for All just came out. Its conclusion: a single-payer system would guarantee health insurance to all people while reducing overall health spending by hundreds of billions of dollars every year.

21.12.2020 - 09:00 [ Wiley Online Library ]

The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin

(17.11.2020)

We here describe how the two main SARS‐CoV‐2 features, (1) the presence of a furin cleavage site missing in other CoVs of the same group and (2) an receptor binding domain (RBD) optimized to bind to human cells[2] might be the result of lab manipulation techniques such as site‐directed mutagenesis. The acquisition of both unique features by SARS‐CoV‐2 more or less simultaneously is less likely to be natural or caused only by cell/animal serial passage.

02.12.2020 - 16:10 [ Wiley Online Library ]

The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin

(17.11.2020)

We here describe how the two main SARS‐CoV‐2 features, (1) the presence of a furin cleavage site missing in other CoVs of the same group and (2) an receptor binding domain (RBD) optimized to bind to human cells[2] might be the result of lab manipulation techniques such as site‐directed mutagenesis. The acquisition of both unique features by SARS‐CoV‐2 more or less simultaneously is less likely to be natural or caused only by cell/animal serial passage.

02.12.2020 - 15:54 [ DailyMail.co.uk ]

How did Covid REALLY spread around the world? As damning test results show antibodies were in US in December – WEEKS before China raised the alarm – growing global evidence points to a cover-up

– Blood samples unveiled this week show people in California, Oregon and Washington infected in December
– Further tests on blood taken in mid-to-late December and into early January found virus in six more states
– Italy, Brazil and France have all since found traces of the virus before China even acknowledged it existed
– Evidence has emerged in Spain and the UK suggesting that Covid-19 was around before testing was possible
– Claims the virus emerged in a market in Wuhan last winter have crumbled in the face of scientific evidence

09.08.2020 - 08:07 [ journals.plos.org ]

The Earth’s magnetic field in Jerusalem during the Babylonian destruction: A unique reference for field behavior and an anchor for archaeomagnetic dating

Archaeomagnetism, the application of paleomagnetic methods to archaeological materials, is interdisciplinary not only in its methods but also in its impact. Well-dated archaeological materials are a critical data source for geomagnetic secular variation models [1–6], which are used to explore the dynamic structure of Earth’s core [7, 8], the rates of cosmogenic isotope production in the atmosphere [9–11] and the possible effect of geomagnetism on climate [11–13]. Precise documentation of the ancient field also helps contextualize geomagnetic observations from the modern era, such as the evolution of the South Atlantic Anomaly [14, 15] and the ongoing decline in the field’s intensity [16–18].

09.08.2020 - 08:05 [ Haaretz ]

Ruins of Ancient Jerusalem Help Unravel Enigmas of Earth’s Magnetic Field

Albert Einstein once called the behavior of the magnetic field one of the great mysteries of physics, but understanding and possibly predicting its changes has taken on a new urgency for scientists. The field has lost around 10 percent of its strength since measurements began less than 200 years ago, leading some researchers to question whether we are on the way to a flip in polarity, which would be preceded by a loss of our precious shield against cosmic radiation.

30.07.2020 - 02:52 [ Telegraph.co.uk ]

‚Lockdown has killed 21,000 people‘, say experts

The study by economists and academics from Sheffield and Loughborough universities suggests more than 21,000 people died as a result of the measures introduced in March.

The analysis examines Office for National Statistics (ONS) data in the eight weeks that followed the national lockdown.

Researchers said the findings show that “lockdown has killed 21,000 people” because the policy has had “significant unintended consequences” such as lack of access to critical healthcare and a collapse in A&E attendances.

09.07.2020 - 18:49 [ ReclaimTheNet.org ]

Twitter mob: College researcher forced to resign after study finding no racial bias in police shootings

And while 800 people supported a petition to fire him, more than 2,000 backed him with their signatures, including top academics such as Harvard’s Steven Pinker, as well as MSU professors who said there is “zero concrete evidence that Hsu has performed his duties as VP in an unfair or biased manner.”

“Therefore, removing Hsu from his post as VP would be to capitulate to rumor and character assassination,” the petition said.