Archiv: Oxford vaccine ChAdOx1 nCoV-19 (AZD1222 / Covishield / Vaxzevria) / Oxford vaccine


01.04.2021 - 23:48 [ DailyMail.xo.uk ]

Now EUROPE goes to India in an attempt to buy 10m extra doses of AstraZeneca vaccine while Delhi blocks shipment of 5m jabs to Britain

The European Union has approached India in a bid to buy 10million doses of the AstraZeneca jab from its Serum Institute, as the bloc desperately scrambles to procure more vaccine supplies.

Britain has already blamed India’s export ban for delaying the shipment of five million doses to the UK and restricting the country’s vaccine drive to mainly administering second doses to the over-50s in April.

30.03.2021 - 23:01 [ DailyMail.co.uk ]

Germany BANS AstraZeneca jab for under-60s over unproven blood clot fears despite British scientists insisting there’s NO evidence it increases risks

– German health officials banned use of AstraZeneca vaccine in under-60s
– Earlier Berlin’s Charite hospital banned AZ jabs for women under the age of 55
– It comes despite authoritative rulings by experts that the jab is safe and effective
– Canada yesterday banned AZ jab for under-55s over the blood clot concerns

30.03.2021 - 22:36 [ Haaretz ]

Does Israel Really Need 30 Million More COVID Vaccine Doses?

Levy, the ministry’s director general, points to Europe’s potential ban on exporting the vaccine beyond the continent, particularly to countries such as Israel, where vaccination levels are high. If Israel signs the new contracts, it might be protected against such export bans. The ministry is also hastening Israel to sign contracts prior to the completion of clinical trials of the vaccine on children, before stiff international competition sets in.

30.03.2021 - 16:29 [ DailyMail.co.uk ]

More than HALF of people in England now have Covid antibodies thanks to huge vaccination drive and natural immunity – with PM facing more calls to lift restrictions NOW as lockdown-weary Brits head to beaches and parks to sizzle on hottest day of the year

One Tory MP told MailOnline the PM must bring forward the arbitrary dates in order to ‚maintain public confidence that we are getting our freedom as soon as possible‘. Steve Baker, of the Covid Recovery Group, called on No10 to ask SAGE to see whether the relaxation of restrictions could be safely brought forward.

27.03.2021 - 14:00 [ Express.co.uk ]

What’s the point of a BRILLIANT vaccine if we remain prisoners in our homes? JUDY FINNIGAN

I’m getting very tired of various scientific oddbods turning up on the news and telling us our future. This is invariably gloomy, speculating about how new variants will not allow us to have holidays abroad this summer.

The latest – unbelievably – is Professor Neil Ferguson, who was so publicly caught flouting his own lockdown advice last year by inviting his mistress over for a spot of nooky.

Shamed for a bit, he’s now back on his high horse, saying summer holidays are not for the rest of us.

27.03.2021 - 13:52 [ Yahoo.com ]

Boris Johnson sends envoy to Serum Institute for vaccine deal with India

UK prime minister Boris Johnson has sent an envoy to India to secure millions of doses of the AstraZeneca (AZN.L) COVID-19 vaccine.

Lord Eddie Lister, the PM’s Conservative peer, and international adviser David Quarrey, met with India’s foreign secretary Harsh Shringla in New Delhi on Monday.

27.03.2021 - 13:16 [ Standard.co.uk ]

UK ‘to speed up Covid vaccine rollout’ as EU stops short of export ban

Britain is set to speed up its “world-leading” vaccine roll-out in coming months after the EU stopped short of imposing a ban on exports of jabs across the Channel, a Cabinet minister said today.

Communities Secretary Robert Jenrick stressed that more vaccination supplies were due to arrive in the UK during the spring and summer.

27.03.2021 - 12:38 [ theGuardian.com ]

France claims UK will struggle to source second Covid jabs

“The UK is proud to have vaccinated many people with the first dose, but they will have a problem with the second dose,” Le Drian said. “And we are fully vaccinated with two doses, not one. Today we have the same number of fully vaccinated people in France and the United Kingdom.

25.03.2021 - 18:09 [ theTimes.co.uk ]

EU contract with AstraZeneca is inferior to UK’s, says Matt Hancock

Britain negotiated a better contract to secure vaccine supplies with AstraZeneca that trumps the EU’s agreement with the company, the health secretary has said.

EU leaders will today discuss European Commission proposals for export bans if there are new supply shortages this spring amid a dispute over who gets a stock of four million doses made by AstraZeneca’s Dutch factory.

25.03.2021 - 18:07 [ Tagesschau.de ]

Großbritannien zu AstraZeneca-Impfstoff „Unser Vertrag übertrumpft deren“

Mit Blick auf den Streit zwischen der EU und AstraZeneca über gekürzte Liefermengen sagte Hancock der „Financial Times“: „Unser Vertrag übertrumpft deren. Das nennt sich Vertragsrecht und ist eindeutig.“ Die EU habe einen Vertrag, der lediglich „beste Bemühungen“ seitens des Impfstoffherstellers zusichere, London habe sich hingegen Exklusivität zusichern lassen.

22.03.2021 - 16:49 [ DailyMail.co.uk ]

Boris ‚will offer to SHARE millions of doses of AstraZeneca’s jab made at Dutch factory with the EU‘ as he warns a THIRD Covid wave will ‚wash up on our shores‘ from Europe

The PM is appealing to other leaders in a bid to resolve the crisis without a clash, and he spoke with continental heavyweights Angela Merkel and Emmanuel Macron last night to try and persuade them to soften their stance. He has also sent Lord Lister, a government ally, to India to ease tensions over the delay to a batch of five million UK-bound doses of the same vaccine.

21.03.2021 - 18:49 [ DavidAllenGreen.com ]

What the AstraZeneca agreement actually says

(31.01.2021)

First, the parties.

The agreement is between the European Commission, acting on behalf of European Union member states, and AstraZeneca AB, incorporated in Sweden.

That this is the AstraZeneca entity that is party to the agreement may be significant, for (all other things being equal) only that entity will be bound by obligations on AstraZeneca in the agreement – and not any other AstraZeneca entity.

21.03.2021 - 18:43 [ Express.co.uk ]

EU vaccine export ban: Can Ursula von der Leyen REALLY block jab export? Is it legal?

Ms von der Leyen said Brussels had the right to ban the export of vaccines to the UK. But according to a UK Government official, such a move would be illegal.

The source told the Daily Mail: “The reality is our contract with AstraZeneca is rock-solid and better than the EU’s.

“And we’re only getting what we helped to develop and paid for.”

21.03.2021 - 13:44 [ IndiaToday.in ]

UK to slow Covid vaccine rollout, PM Johnson says delay due to shipment from India’s Serum Institute

(19.03.2021)

The United Kingdom (UK) will have to slow its Covid-19 vaccine rollout in April due to a supply crunch caused by a delay in a shipment of millions of AstraZeneca vaccines from the Serum Institute of India.

21.03.2021 - 13:43 [ DailyMail.co.uk ]

MAIL ON SUNDAY COMMENT: The EU elite’s seething resentment at Britain’s success hurts them more than us and does no one any good

The grotesque behaviour of EU governments and leaders over the Oxford vaccine has gone beyond all limits of reason and civilised action.

First, they attacked its usefulness. Then they cast doubts on its safety. Now they seek to grab hold of supplies, and so slow down its distribution in one of the few countries that has welcomed and used it widely and effectively.

21.03.2021 - 13:30 [ Al Jazeera ]

EU threatens to ban AstraZeneca exports if vaccines not delivered

Von der Leyen said Anglo-Swedish pharma giant AstraZeneca had delivered only 30 percent of the 90 million vaccine doses it had promised for the first quarter of the year.

The company has blamed production delays at its EU plants, but European officials are furious that AstraZeneca has been able to deliver its United Kingdom contract while falling short on the continent.

21.03.2021 - 13:26 [ Politico.eu ]

AstraZeneca cuts EU vaccine delivery targets again

(12.03.2021)

But the 180 million doses expected in the second quarter are now also in jeopardy, since half of these doses were planned to be sourced from the global supply chain.

21.03.2021 - 13:14 [ theGuardian.com ]

Brazil, Saudi Arabia and Morocco ‚told of delay in Covid jabs from India‘

The Serum Institute of India (SII) has told Brazil, Saudi Arabia and Morocco that further supplies of the Oxford/AstraZeneca Covid-19 vaccine will be delayed because of surging demand at home and work on capacity expansion, a source with direct knowledge of the matter said.

19.03.2021 - 06:32 [ The Sun / Youtube ]

Boris Johnson vows ‘roadmap to freedom’ will NOT be delayed despite AstraZeneca jab supply fears

BORIS Johnson has reassured Brits that the AstraZeneca jab is safe and effective – as he calmed nerves about the country’s vaccine rollout.

19.03.2021 - 06:14 [ DailyMail.co.uk ]

‚We over-promised again‘: Matt Hancock faces Tory backlash as he FINALLY admits that India IS behind jabs delay with four million AstraZeneca doses held back by Delhi in ‚act of vaccine nationalism‘ – dealing serious blow to UK’s rollout

– Matt Hancock under fire for raising hopes of huge ramp up in vaccines only for supplies setback to emerge
– Serum Institute of India has been told it must hand jabs to its own citizens before exporting vaccine stocks
– One batch of five million doses of the AstraZeneca jab bound for the UK has been delayed by a month
. Confusingly Boris Johnson insisted Indian government has not blocked any exports, as he prepares to visit

19.03.2021 - 06:07 [ ZDF ]

Spahn nach EMA-Entscheidung – Astrazeneca-Impfungen gehen am Freitag weiter

Ab morgen soll es weitergehen mit der Astrazeneca-Impfkampagne. Das kündigte Gesundheitsminister Spahn an.

19.03.2021 - 06:03 [ Heise.de ]

EMA zu AstraZeneca: „Guter und sicherer Impfstoff“

(18.03.2021)

Die Bundesregierung hatte zuvor angekündigt, dass sie sich nach der EMA-Entscheidung richten werde. „Es ist klar, dass wir dieser Entscheidung folgen“, sagte der Sprecher des Gesundheitsministeriums, Hanno Kautz, am gestrigen Mittwoch.

18.03.2021 - 12:04 [ Express.co.uk ]

‘Is VDL being pressured by Germany?!’ Macron aide speechless at C4 Covid vaccine probe

Channel 4 News presenter Matt Frei asked: „Is this all very political and does Ursula von der Leyen, as a German politician and member of Angela Merkel’s ruling CDU, is she now under pressure?

„Especially after the results of the regional elections on Sunday that she has to come out and take the gloves off.

„Is that what this is? Is it political?“

Ms Trillet-Lenoir replied: „I wouldn’t say so. I would say it’s a complicated explanation.

18.03.2021 - 12:00 [ Express.co.uk ]

BBC’s Katya Adler exposes why Italy ‚under pressure‘ to suspend AstraZeneca vaccine

BBC’s Katya Adler insisted that Italy felt under pressure to suspend the rollout of the AstraZeneca Covid vaccine. While speaking on Newscast, she said despite its own advisors saying not to suspend the use of the vaccine, the Italian Government decided to plough ahead with the temporary ban. She claimed this was due to mounting pressure from their citizens with concerns due to bigger European nations Germany and France suspending the vaccine.

18.03.2021 - 11:55 [ Wall Street Journal ]

Germany, France, Italy Suspend Use of AstraZeneca’s Covid-19 Vaccine

(15.03.2021)

Germany, Italy, France and Spain joined the ranks of European countries that have temporarily halted use of the Covid-19 shot made by AstraZeneca PLC over blood-clot concerns, dealing another blow to the continent’s sluggish vaccination rollout and threatening the credibility of the vaccine itself.

18.03.2021 - 11:50 [ Heise.de ]

Corona-Krise wird Regierungskrise: Frankreich in der Falle

„Ist die Regierung in die Falle ihrer europäischen Partner getappt, insbesondere Deutschland, das am Montag beschlossen hat, den Impfstoff auszusetzen?“, fragt Le Monde.

Die Zeitung Libération geht noch weiter: Macron habe sich von der Bundesregierung unter Handlungszwang gesetzt gesehen. Mit seiner Pressekonferenz habe Gesundheitsminister Jens Spahn (CDU) den französischen Präsidenten kurz vor dessen geplanten Presseauftritt an der Seite des spanischen Ministerpräsidenten Pedro Sánchez unter Druck gesetzt:

17.03.2021 - 01:55 [ DailyMail.co.uk ]

Pfizer’s Covid vaccine is linked to MORE blood clots than AstraZeneca’s – so why isn’t the EU banning it? Hypocrisy of European nations revealed as Italy admits decision was ‚POLITICAL‘

And data from the Medicines and Healthcare products Regulatory Agency (MHRA) regulator in the UK show more people have reported blood clots after having Pfizer’s vaccine than the Oxford one — even though Pfizer’s jab has not been suspended anywhere.

Up to February 28 there were 38 reports from approximately 11.5million doses of Pfizer’s jab, compared to 30 from 9.7m AstraZeneca doses. However, neither figure – the equivalent of one blood clot seen in every 367,000 jabs – is thought to be higher than the risk expected in the general population.

16.03.2021 - 11:44 [ Boris Johnson - Gov.uk ]

PM Boris Johnson: The Oxford vaccine shows why we and the world need Britain to be global

The objective of Global Britain is not to swagger or strike attitudes on the world stage. It is to use the full spectrum of our abilities, now amplified by record spending on both defence and science, to engage with and help the rest of the world. That is how we serve the British interest, and I mean the economic interest of people up and down the country. And as the vaccine programme begins to inspire a new global hope, we want to use this moment to heal, both literally and figuratively.

16.03.2021 - 11:18 [ DailyMail.co.uk ]

‚Your Brexit sulk will cost lives‘: MPs from all parties and the WHO plead with Britons to keep taking ’safe‘ AstraZeneca vaccine amid fury that EU’s ‚fake news‘ has fuelled anti-vax campaign as Sweden joins 12 countries suspending jab

As Sweden became the latest European country to suspend the Oxford vaccine over unproven fears it causes blood clots, politicians, medics and scientists have launched a concerted effort to reassure the public about safety.

France, Germany, Spain and Italy are also among the states to act despite the European Medicines Agency dismissing the link, with warnings that the pausing of inoculations is ‚reckless‘ and will cost lives on the continent.

16.03.2021 - 02:50 [ ABC News ]

WHO: Vaccine rollout unaffected by concerns over AstraZeneca

“We understand these are precautionary measures,“ WHO assistant director-general Mariangela Simao said. “I would like to say this to countries from other regions that are not Europe: That the vaccines (at issue) so far are from European manufacturing not vaccines that are provided through the COVAX facility.”

16.03.2021 - 02:27 [ theGuardian.com ]

Coronavirus live news: keep using AstraZeneca/Oxford vaccine, says WHO

But, Boseley writes, while governments are pulling the plug, most scientists are rolling their eyes, because, so far, there is no evidence that any were caused by the vaccine.

Experts say that the numbers of blood clots and thrombocytopenia cases in people who have been vaccinated is no higher than in the population that has not received the jab

16.03.2021 - 02:17 [ Heise.de ]

Deutschland, Frankreich, Italien: AstraZeneca-Impfung ausgesetzt

Die Entscheidung zur Aussetzung ist keine wirkliche Überraschung – angesichts dessen, dass sich andere Länder, zuerst Dänemark, dann Norwegen, Island, Bulgarien, Irland, die Niederlande und – auf bestimmte Chargen begrenzt – auch Österreich, Estland, Lettland, Litauen, Luxemburg, Italien und Rumänien zu einem solchen Schritt entschlossen hatten und dazu auch Fälle von schweren Blutgerinnseln zur Begründung angegeben wurden.

15.03.2021 - 08:45 [ DailyMail.co.uk ]

Netherlands joins growing list of EU nations to suspend use of AstraZeneca jab over blood clot fears as Bloc’s battle against virus falters with new lockdown in Italy and cases spiking in France with hospitals over-run

It comes as Dutch voters deliver their verdict on the country’s coronavirus response in the first of three days of voting in a snap election, weeks after a curfew prompted three nights of rioting across major cities.

The Netherlands is the fifth country to pause its roll-out, following Ireland, Denmark, Iceland and Norway. Italy and Austria stopped using one particular batch of the jab.

13.03.2021 - 13:59 [ Tagesschau.de ]

Vereinbarte Impfstoff-Lieferung: AstraZeneca kürzt erneut Nachschub für EU

Der Konzern begründete dies gestern so: „Leider werden Exportbeschränkungen die Lieferungen im ersten Quartal nun reduzieren, und werden dies wahrscheinlich auch im zweiten Quartal.“ Weitere Details wurden nicht genannt

13.03.2021 - 13:52 [ Tagesschau.de ]

AstraZeneca: Warum die USA keinen Impfstoff abgeben

Die US Regierung wehrt sich gegen Vorwürfe, sie würden Hersteller mit einem Exportstopp daran hindern, zugesagten Impfstoff nach Europa zu liefern. Es gebe kein Exportverbot. Der Impfstoff im Kühlschrank gehöre den USA, sei gekauft und bezahlt, den gebe man nicht einfach ab. Das habe nichts mit Exportverbot zu tun.

12.03.2021 - 08:48 [ Tagesschau.de ]

Johnson & Johnson: Warum punktet der neue Impfstoff?

Damit ist die Wirkungsweise von Johnson & Johnson die gleiche, wie die des Impfstoffs von AstraZeneca, nur dass beide unterschiedliche Trägerviren verwenden.

Bei den neuartigen mRNA-Impfstoffen von BioNTech/Pfizer und Moderna werden hingegen keine Viren oder Teile von Viren geimpft, sondern direkt ein Teil des Coronavirus-Erbgutes. Diese genetische Information funktioniert wie ein Bauplan

05.03.2021 - 08:22 [ ORF.at ]

Australien über Impfstofflieferstopp aus EU enttäuscht

„Wir haben bis zu 150 Millionen Dosen Impfstoff in Auftrag gegeben, davon 50 Millionen Dosen, die hier in Australien produziert werden sollen“, sagte er. Die Welt befinde sich derzeit in einem ziemlich unerforschtem Gebiet, da sei es wenig überraschend, „dass einige Länder das Regelbuch zerreißen werden“.

Italien hatte EU-Kreisen zufolge die Lieferung von 250.000 Dosen Impfstoff des britisch-schwedischen Herstellers AstraZeneca an Australien verhindert –

05.03.2021 - 08:19 [ Tagesschau.de ]

AstraZeneca-Lieferung: Erstmals Impfstoff-Export aus der EU gestoppt

Erstmals ist die Ausfuhr von Corona-Impfstoff aus der Europäischen Union in einen Drittstaat gestoppt worden. Italien verhinderte die Lieferung von 250.000 Dosen Impfstoff des britisch-schwedischen Herstellers AstraZeneca nach Australien, wie das Außenministerium in Rom mitteilte. Die Dosen stammen demnach aus einer Fabrik in Italien, die von AstraZeneca betrieben wird. Die EU habe der Anordnung aus Rom zugestimmt.

24.02.2021 - 13:33 [ Tagesschau.de ]

AstraZeneca kann wohl Zusagen nicht einhalten

Der britisch-schwedische Konzern habe in internen Gesprächen erklärt, im zweiten Quartal „weniger als 90 Millionen Einheiten“ zu liefern, so der EU-Vertreter, der nach eigenen Angaben in die Gespräche eingebunden war.

22.02.2021 - 08:01 [ ORF.at ]

AstraZeneca: Ärger in Italien wegen Lieferproblemen

Wie aus einer Mitteilung des Unternehmens hervorgeht, will AstraZeneca nun bis Ende März 4,2 Millionen Dosen liefern. Die Regierung hatte mit acht Millionen Dosen für die ersten drei Monate gerechnet.

17.02.2021 - 17:05 [ Spiegel ]

Spahn gibt neue Daten bekannt: Anteil britischer Mutante in Deutschland bei mehr als 20 Prozent

Die ansteckendere Corona-Variante aus Großbritannien macht bei den Neuinfektionen in Deutschland mittlerweile einen deutlich größeren Anteil aus. Laut Gesundheitsminister Spahn könnte sie bald dominierend sein.

17.02.2021 - 16:45 [ Jasmine the European Cat / Twitter ]

But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce.

(09.02.2021)

It expects to have a vaccine designed to address the variant discovered in South Africa ready by autumn.

17.02.2021 - 16:35 [ usatodaysun.com ]

AstraZeneca expects updated COVID-19 vaccine by autumn

(14.02.2021)

The Anglo-Swedish company, which makes a vaccine developed by the University of Oxford, said it is working with the university’s scientists to adapt the shot to combat new variants.

17.02.2021 - 16:31 [ MSN.com ]

Masks and social distancing could stay until AUTUMN at earliest – sources

(12.02.2021)

SAGE member Professor John Edmunds painted a darker picture and suggested the measures could last even longer.

He told ITV’s Peston face masks could be required „probably forever“ if COVID-19 becomes endemic in the UK.

17.02.2021 - 16:22 [ DailyMail.co.uk ]

New Covid vaccines could be made in 40 DAYS if they need updating to tackle mutated variants, taskforce chief says

Dr Dix added: ‚I think 40 days would be a real stretch but we would aim for something as good as that.

‚But certainly within 60 days and then, after that, we would start the manufacturing.‘

Manufacturing vaccines takes different amounts of time depending on the type of jab.

15.02.2021 - 22:34 [ BMJ.com ]

Why did a German newspaper insist the Oxford AstraZeneca vaccine was inefficacious for older people—without evidence?

With huge global public health implications, Handelsblatt’s story rapidly became international news—and was rapidly rebuffed. Calls for the underlying data filled social media. An AstraZeneca spokesperson described the reported figure as “completely incorrect.”

The controversy came at a moment of intense finger pointing between the European Commission and AstraZeneca over unfulfilled vaccine shipments, and in the week that the European Medicines Agency (EMA) was expected to decide whether to recommend authorisation.

15.02.2021 - 22:20 [ ORF.at ]

WHO erteilte Notfallzulassung für AstraZeneca

Für Länder wie Großbritannien, die USA oder die Mitglieder der EU und viele weitere spielt die WHO-Notfallzulassung keine Rolle. Sie machen selbst Risikoanalysen und entscheiden über eine Zulassung.

15.02.2021 - 22:14 [ NBC News ]

WHO approves AstraZeneca/Oxford Covid-19 vaccine for emergency use

„We continue to call for Covid-19 vaccine developers to submit their dossiers to WHO for review at the same time as they submit them to regulators in high-income countries,“ he said.

A WHO statement said it had approved the vaccine as produced by AstraZeneca-SKBio (Republic of Korea) and the Serum Institute of India.

15.02.2021 - 05:53 [ DailyMail.co.uk ]

Single jabs of Covid vaccine are providing 67% protection against infections, data reveals as experts say delaying second dose is ‚paying off‘

Prof Spector said that he no longer watched the Government’s daily briefings as he felt the statistics were not presented in context, particularly the death rates.

He said: ‚It’s very sad people die of anything. Yesterday around 600 people died of Covid but on a normal day in February 1,500 people die of heart disease, strokes, cancer etc or the flu.

‚This has got a lot of people extremely anxious and are petrified to leave their homes and may have problems coming out if we do not put those statistics into context.

‚People are dying of Covid but people die of other things. I would like to see less fear-mongering.‘

13.02.2021 - 19:36 [ Telegraph.co.uk ]

Oxford Covid-19 vaccine Q&A: How effective is it, and how is it different to the Pfizer vaccine?

According to new results, a single dose of the Oxford-AstraZeneca vaccine prevents two-thirds of Covid transmissions, raising hopes for the easing of restrictions by Easter.

The data, released on Feb 2, also revealed that the first jab prevents 100 per cent of hospitalisations after 22 days once an immune response has had time to develop.

13.02.2021 - 19:21 [ DailyMail.co.uk ]

Boris says he’s ‚optimistic‘ about easing lockdown starting with schools in March and we will ‚learn to live with‘ Covid – as leaked data shows hospitalisations falling much FASTER than expected

Modelling by Sage presented to Downing Street and leaked to The Times predicts hospital admissions and deaths will more than halve over the next month.

Patients battling coronavirus in hospital currently number around 24,000, but this figure is expected to be slashed to around 9,000 by mid-March.

Yesterday 1,908 patients were taken to hospital in the UK, a massive drop in admission rates since the peak in January when around 4,500 were admitted on a single day.

12.02.2021 - 07:15 [ Politico.eu ]

Belgian plant blamed for AstraZeneca vaccine shortage says it met all deliveries

(10.02.2021)

AstraZeneca subcontracted the plant — previously owned by Novasep — to produce the drug substance of its vaccine. Volanti would not say how many doses the plant was contracted to provide. He said the plant sends its drug substance to an Italian company to be put into vials and packaged for distribution.

AstraZeneca declined to comment on Thermo Fisher’s remarks, according to Reuters.

12.02.2021 - 07:11 [ Jasmine the European Cat / Twitter ]

But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce.

(09.02.2021)

12.02.2021 - 07:07 [ theGuardian.com ]

AstraZeneca says vaccine against new Covid variants may take six months

AstraZeneca has said it could take between six and nine months to produce Covid-19 vaccines that are effective against new variants of the coronavirus, and begin administering them to the public.

10.02.2021 - 16:55 [ NDR ]

Astrazeneca will in Dessau investieren

Der britisch-schwedische Pharmahersteller AstraZeneca will die Produktion von Corona-Impfstoffen in Europa ausweiten. Der Konzern wird dafür mit der Firma IDT Biologika in Sachsen-Anhalt zusammenarbeiten.

09.02.2021 - 21:03 [ Jasmine the European Cat / Twitter ]

But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce.

It expects to have a vaccine designed to address the variant discovered in South Africa ready by autumn.

09.02.2021 - 20:57 [ theGuardian.com ]

How can Covid vaccines be tweaked to tackle new variants?

Production BioNTech has said it can produce a fresh vaccine within six weeks of a decision being made. But the Oxford/AstraZeneca team, which uses more traditional viral vector technology, says that while it can make a new formulation in days, it takes much longer to produce

09.02.2021 - 20:53 [ CNN ]

Why bad news for AstraZeneca’s vaccine is a roadblock on the way out of the pandemic

The study from South Africa suggested that two doses of the AstraZeneca vaccine provided „substantially reduced“ protection against mild to moderate Covid-19 disease from the new virus variant first identified there, known as B.1.351.

The study has not yet been peer reviewed or published in full, so many unknowns remain. What we do know is that it included a relatively small number of volunteers who were predominantly young and healthy and therefore not likely to suffer from severe Covid-19 disease.

09.02.2021 - 20:42 [ DailyMail.co.uk ]

Tories savage Matt Hancock over ’never-ending lockdown‘ as UK’s Covid second wave continues to shrink: Cases and deaths drop 27% with 12,364 infections and 1,052 victims – but Health Secretary warns border restrictions may still be in place until AUTUMN

But hopes the world-beating vaccine roll-out will mean lockdown curbs can be significantly eased any time soon were shot down today by Mr Hancock, who unveiled the latest suite of border curbs and warned they could last until the Autumn when booster vaccines will be available.

09.02.2021 - 12:34 [ DailyMail.co.uk ]

Britain could be trapped in lockdown cycles for several YEARS in fight with Covid variants – but staying in tougher measures for longer now will prevent new vaccine-resistant strains, SAGE scientists warn

Evidence suggests the Oxford University vaccine – the main weapon in Britain’s arsenal to combat the virus – does not stop people falling ill with the South African variant, which is feared to be spreading in the community already.

08.02.2021 - 16:34 [ Reuters ]

New COVID-19 variant defeats plasma treatment, may reduce vaccine efficacy

(20.01.2021)

“This lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies,” the team of scientists from three South African universities working with the National Institute for Communicable Diseases (NICD) wrote in a paper in bioRxiv, a website that publishes scientific research prior to its being peer-reviewed and submitted to journals.

08.02.2021 - 16:22 [ DailyMail.co.uk ]

AstraZeneca is working on Covid vaccine booster ‚that will be ready by autumn‘ to beat South African strain after research showed its current version had ‚minimal‘ effect on stopping it

Professor Gilbert earlier told the BBC’s Andrew Marr Show that her team currently has ‚a version with the South African spike sequence in the works‘ with hopes it will be ready to administer by the autumn.

‚It’s not quite ready to vaccinate people with yet, but, as all of the developers are using platform technologies, these are ways of making a vaccine that are very quick to adapt,‘ she added.

08.02.2021 - 16:16 [ DailyMaverick.co.za ]

South Africa switches to J&J’s ‘silver bullet’ as AstraZeneca vaccine falters against local variant of coronavirus

“Unfortunately, viruses mutate. Sometimes this is by accident. But often the reason is that the virus wants to become more adept to infect the host.”

This, Madhi explained, was what had happened with the South African variant as well as another variant that was first identified in the United Kingdom.

07.02.2021 - 15:40 [ University of Oxford ]

Oxford coronavirus vaccine shows sustained protection of 76% during the 3-month interval until the second dose

(02.02.2021)

The authors also report further on the potential for the vaccine to reduce transmission of the virus, based on swabs obtained from volunteers in the UK arms of the trial with a 67% reduction after the first dose of the vaccine.

06.02.2021 - 13:18 [ Tagesschau.de ]

Erste AstraZeneca-Impfdosen werden geliefert

Einer Liste des Gesundheitsministeriums zufolge erhalten die Bundesländer insgesamt knapp 350.000 Impfdosen von dem britisch-schwedischen Hersteller. Für die kommende Woche ist eine weitere Lieferung von 390.000 Dosen des jüngst zugelassenen Wirkstoffs angekündigt.

06.02.2021 - 12:21 [ ORF.at ]

„Impfdiplomatie“: Vakzine als Pfand im Rennen um Einfluss

Chinas Zusage an Covax wird als Reaktion auf Indien gewertet, das in der Verteilung von Impfstoffen an andere Staaten inzwischen eine Führungsrolle übernommen hat. Zuletzt unterstützte Indien das schwer von der Pandemie getroffene Südafrika mit einer Million Covishield-Dosen, weitere 500.000 sollen bis Ende Februar folgen. Zuvor hatte Indien bereits zugesagt, rund 20 Mio. Dosen an Nepal, Bangladesch, Sri Lanka, Afghanistan, die Seychellen und Mauritius zu verkaufen oder zu spenden.

05.02.2021 - 21:16 [ theSun.co.uk ]

UK Covid cases fall by a THIRD in a week and deaths down almost 20% piling pressure on Boris to show way out of lockdown

Mark Harper — chairman of the Covid Recovery Group of lockdown sceptics, with 70 Tory MPs — said: “Back-of-the-envelope calculations I did based on two million doses a week mean you could get the top nine priority groups, first doses, and the top four groups, second doses, all done by the end of May.

“So it seems to me by the time you get to the end of May, no later than that, you should be in a position to get rid of restrictions completely.

02.02.2021 - 23:55 [ Social Science Research Network ]

Single dose administration, and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine

If there was no impact of a vaccine on asymptomatic infection, it would be expected that an efficacious vaccine would simply convert severe cases to mild cases and mild cases to asymptomatic, with overall PCR positivity unchanged. A measure of overall PCR positivity is appropriate to assess whether there is a reduction in the burden of infection. Analyses presented here show that a single standard dose of the vaccine reduced PCR positivity by 67%, and that, after the second dose, the SD/SD schedule reduced PCR positivity by 49.5% overall. These data indicate that ChAdOx1 nCoV-19, used in the authorised schedules, may have a substantial impact on transmission by reducing the number of infected individuals in the population.

02.02.2021 - 23:55 [ DailyMail.co.uk ]

Single shot of Oxford University’s Covid jab ‚is 76% effective for 12 weeks and may block seven in 10 people from spreading the disease‘

Meanwhile, analysis of PCR positive swabs carried out on nearly 7,000 patients in the UK arm of Oxford’s trial suggests the vaccine may reduce transmission by 67 per cent.

02.02.2021 - 21:28 [ DailyMail.co.uk ]

AstraZeneca Covid-19 vaccine will not be recommended for over-65s in France or Sweden as countries follow Germany’s lead

The Oxford AstraZeneca vaccine will not be recommended for over-65s in France or Sweden, the countries‘ health ministries announced today.

It comes after Germany advised against administering the jab to those over 65 and Emmanuel Macron claimed it was ‚almost ineffective‘ for the age bracket.

Continental objections to the jab last week came amid a furious row between the Bloc and AstraZeneca over lagging supply, which has seen newly-unshackled Brexit Britain storm ahead in its immunisation roll-out.

29.01.2021 - 16:50 [ Tagesschau.de ]

EMA gibt AstraZeneca-Vakzin frei

Die europäische Arzneimittelagentur EMA hat die Zulassung des Corona-Impfstoffs von AstraZeneca in der EU empfohlen. Die finale Entscheidung liegt nun bei der EU-Kommission. Die Zustimmung gilt als Formsache.

29.01.2021 - 15:35 [ ec.europa.eu ]

Vaccines: contract between European Commission and AstraZeneca now published

Following the renewed request from the European Commission on 27 January 2021, pharmaceutical company AstraZeneca has agreed to publish the redacted contract signed between the two parties on 27 August 2020.

The Commission welcomes the company’s commitment towards more transparency in its participation in the rollout of the EU Vaccines Strategy.

29.01.2021 - 15:30 [ ZDF ]

Streit mit Astrazeneca – EU veröffentlicht Impfstoff-Vertrag

Astrazeneca hat nun zugestimmt, den Vertrag, der am 27. August zwischen EU und dem Pharmaunternehmen unterzeichnet wurde, zu veröffentlichen. Die Brüsseler Behörde stellte das 41 Seiten lange Dokument am Freitag auf ihre Webseite. [Hier können Sie die den Vertrag, der von der EU veröffentlicht wurde, im englischen Original einsehen.]

29.01.2021 - 05:12 [ theGuardian.com ]

Why has Germany advised against Oxford/AstraZeneca jab for over-65s?

Prof Andy Pollard, of the University of Oxford, said the lack of data is understandable. “In our trials, the older adults were recruited later and, because they were recruited later there has been less time for cases to occur, and, older adults are known to be more cautious in the pandemic, meaning the ‘attack rate’ is lower,” he said.

AstraZeneca has stressed that older adults were recruited later because the team wanted to be sure the vaccine was safe before administering it to older age groups.

29.01.2021 - 05:10 [ Dr. ASeidler - Infektiologie / Twitter ]

#STIKO des #RKI empfiehlt den #Impfstoff von #AstraZeneca nicht für Personen über 65 Jahre. Die #Zulassung seitens der #EMA #EU steht noch aus.

29.01.2021 - 04:44 [ Telegraph.co.uk ]

Nicola Sturgeon accused of siding with EU over vaccinations

Nicola Sturgeon has been accused of siding with the EU in its battle with the UK over vaccine doses, with the Scottish First Minister pledging to publish confidential vaccine data despite warnings that the information could jeopardise the UK’s supply.

Ms Sturgeon promised to publish the data – which reveals how many vaccine doses her nation expects each week – to counter claims that she is failing to rollout the vaccine in Scotland at speed.

29.01.2021 - 04:14 [ DailyMail.co.uk ]

Nicola Sturgeon is accused of taking the EU’s side and risking vaccine rollout as she vows to publish details of UK’s supplies despite Boris Johnson ordering her to keep them secret – as Brussels claims AstraZeneca is giving Britain too much

Despite the PM warning that the information must be confidential to protect the rollout, Ms Sturgeon told Holyrood she will release it from next week ‚regardless of what they say‘.

The timing of Ms Sturgeon’s intervention was particularly provocative given that it came as Mr Johnson was on an official visit to Scotland to make the case for the Union.

29.01.2021 - 03:43 [ Tagesschau.de ]

AstraZeneca und die EU: Machtprobe beim Impfstoff

AstraZeneca gehört zu den Pharmaunternehmen, die von der Europäischen Union mit mehreren Hundert Millionen Euro unterstützt werden. 336 Millionen sind allein für AstraZeneca reserviert. Damit sollte die Forschung am Impfstoff beschleunigt und die schnelle Produktion gesichert werden. Ein Teil des Geldes ist schon geflossen, vollständig ausgezahlt ist der Beitrag noch nicht.

Man habe viel vorfinanziert, sagt Kommissionschefin Ursula von der Leyen beim digitalen Weltwirtschaftsforum von Davos, jetzt müsse auch geliefert werden

28.01.2021 - 15:37 [ Tagesschau.de ]

Streit über AstraZeneca-Impfstoff: Hoffen auf einen Kompromiss

Die EU sieht das anders: Man habe dem Unternehmen einen Vorschuss gewährt, um auf Halde zu produzieren. Vor der erwarteten Zulassung des Impfstoffs am Freitag durch die Europäische Arzneimittelbehörde hätte AstraZeneca also längst Impfdosen zurückstellen müssen. Stattdessen habe das Unternehmen die für Europa bestimmten Ampullen nach Großbritannien ausgeliefert.

28.01.2021 - 15:31 [ theHindu.com ]

Vaccine factory in Belgium inspected amid European Union dispute with AstraZeneca

The Novasep’s factory in the town of Seneffe is part of the European production chain for the Oxford-AstraZeneca coronavirus vaccine.

28.01.2021 - 15:27 [ .puls24.at ]

Belgien entsendet Ermittler in AstraZenecas Impfstofffabrik

Beamte der belgischen Arzneimittelbehörde statteten dem AstraZeneca-Standort in Seneffe einen Besuch ab. Die EU-Kommission hatte die Untersuchung angefordert. Sie will wissen, ob auf EU-Gebiet produzierte Dosen nach Großbritannien umgeleitet wurden.

28.01.2021 - 15:07 [ DailyMail.co.uk ]

Germany blocks Oxford jab for over-65s: Panel says data on older people is insufficient – but does not support ‚8% effectiveness‘ claim – amid EU row with Britain over AstraZeneca supplies

AstraZeneca’s vaccine has not been granted approval yet for general use in the European Union, but the bloc’s medicines regulator EMA is poised to authorise it on Friday.

The German panel, STIKO did not detail the data from clinical trials on the vaccine on older people, but two prominent German media outlets had reported that the efficacy on above-65s was below 10 per cent.

27.01.2021 - 19:15 [ SAfm news / Twitter ]

The EU Commission has confirmed that a meeting with the Astrazeneca pharmaceutical company will go ahead later today.

The meeting comes as a row escalates over the supply of its coronavirus vaccine. #sabcnews

27.01.2021 - 16:25 [ ZDF ]

Live: Kyriakides zu Impfstoff-Knappheit

In der EU herrscht Impfstoff-Knappheit. Verfolgen Sie die Pressekonferenz mit der EU-Gesundheitskommissarin Stella Kyriakides jetzt hier im Livestream.

27.01.2021 - 13:45 [ devdiscourse.com ]

India’s Serum Institute says AstraZeneca vaccine output unaffected due to fire

(21.01.2021)

SII has licensed the vaccine developed by Oxford University and AstraZeneca. Many low- and middle-income countries, from Bangladesh to Brazil, are depending on SII delivering the vaccine, known as COVISHIELD in India, to fight the COVID-19 epidemic.

27.01.2021 - 13:37 [ DailyMirror / Twitter ]

500,000 vials of the Oxford Astra Zeneca vaccine will arrive in #SriLanka tomorrow at 11 am on an Air India flight which will be donated by the Indian govt to the Sri Lankan health ministry.

Under this program, 250,000 front line workers will be vaccinated – Lalith Weeratunga

27.01.2021 - 13:00 [ ABC News ]

AstraZeneca says it has not pulled out of talks with the EU on vaccine deliveries, plans meeting later Wednesday

AstraZeneca says it has not pulled out of talks with the EU on vaccine deliveries, plans meeting later Wednesday.

27.01.2021 - 12:38 [ Politico.eu ]

AstraZeneca cancels steering board meeting with EU

The cancellation follows an explosive interview with AstraZeneca CEO Pascal Soriot on Tuesday night, in which he insisted the company didn’t have a contractual obligation but rather a „best effort“ to supply the EU with its vaccine.

Instead of the meeting, the company will respond in writing to Health Commissioner Stella Kyriakides‘ demand for more information, the Commission official said. AstraZeneca did not immediately confirm this plan.

27.01.2021 - 12:22 [ RND / Twitter ]

Der Pharmakonzern #Astrazeneca hat sich aus einem geplanten Treffen mit der EU zu Verzögerungen bei der Lieferung von #Corona-Impfstoffen zurückgezogen.

27.01.2021 - 02:34 [ theDispatch.com/ ]

Is the U.S. Holdup of the Oxford/AstraZeneca Vaccine Justified?

The Oxford/AstraZeneca vaccine has advantages that make it an attractive possibility. It can be stored at normal refrigeration temperatures, and its price is low relative to its competitors. Public health experts have long targeted it as ideal for use in lower and moderate-income countries because of these features.

The problem is that its U.S. Phase III trial was delayed because of an adverse event investigation in the fall, and the data from the international trials used by the U.K. government are difficult to interpret due to unplanned modifications to dosing levels.

27.01.2021 - 01:34 [ theGuardian.com ]

Why experts say there is no basis to claims in Germany about efficacy of AstraZeneca vaccine

A University of Oxford spokesperson said clinical trials showed similar immune responses in younger and older adults, a good safety profile and high efficacy in younger adults. “There is no basis for the claims of very low efficacy of the Oxford/AstraZeneca vaccine which have been circulating in the media,” they said.

While it is true that there was less data from older adults involved in the trials, the team say early figures were promising: “Preliminary efficacy data in older adults supports the importance of this vaccine for use in this population,” they said.

27.01.2021 - 01:12 [ DailyMail.co.uk ]

German media doubles-down on AstraZeneca vaccine stats: Handelsblatt newspaper REPUBLISHES widely rubbished claim that Oxford jab is only 8% effective in Over-65s and says there was NOT a mix-up in its reporting

Handelsblatt was still running the original story today with the headline: ‚Setback to coronavirus vaccine: AstraZeneca vaccine appears to hardly work on seniors‘.

A subheading noted that Germany’s health minister Jens Spahn had been ‚circumspect‘ about the claim, without mentioning the ministry’s subsequent denial.

Gregor Waschinski, one of the journalists behind the story, stood by it on Monday night and said it was confirmed by ‚multiple sources familiar with the German vaccination policy‘.

26.01.2021 - 19:49 [ BBC ]

Coronavirus: Germany rejects ‚mixed up‘ reports on AstraZeneca jab

The reports emerged in Handelsblatt, a respected financial daily, and the mass-circulation Bild, quoting sources within Germany’s governing coalition.

26.01.2021 - 19:38 [ ORF.at ]

Begrenzte Zulassung laut EMA grundsätzlich möglich

Die EU-Arzneimittelagentur (EMA) schließt nicht aus, dass der Coronavirus-Impfstoff von AstraZeneca in Europa nur für eine bestimmte Altersgruppe zugelassen wird. „Ich werde der Entscheidung nicht vorgreifen“, sagte EMA-Chefin Emer Cooke heute in einer Anhörung im Europaparlament. Eine begrenzte Zulassung sei aber grundsätzlich möglich. Das werde genau geprüft.

26.01.2021 - 17:26 [ marketscreener.com ]

ASTRAZENECA HAS PROPOSED TO THE EU TO BRING FORWARD START OF SUPPLIES OF ITS COVID-19 VACCINE TO FEB 7 FROM FEB 15 – EU SOURCES

EXCLUSIVE-ASTRAZENECA HAS PROPOSED TO THE EU TO BRING FORWARD START OF SUPPLIES OF ITS COVID-19 VACCINE TO FEB 7 FROM FEB 15 – EU SOURCES

26.01.2021 - 16:39 [ Reuters ]

EU to monitor vaccine exports, but says it’s not a ban

EU countries learnt late last week that deliveries of the vaccine from AstraZeneca, which is expected to be approved on Friday, would be some 60% lower in the first quarter than initially indicated.

There have also been reduced deliveries of a vaccine jointly produced by Pfizer and BioNTech.

26.01.2021 - 16:32 [ ORF.at ]

Kommission: Keine Exportverbote von CoV-Impfstoffen

„Wir sehen, dass Dosen anderswohin geliefert werden“, sagte der Kommissionssprecher. Da die EU Vorauszahlungen für die Produktion geleistet habe, „sollten diese Dosen eigentlich für die Lieferung verfügbar sein“, sobald die EMA grünes Licht gebe.

AstraZeneca konnte bei zwei Treffen mit der EU-Kommission und den Mitgliedsstaaten gestern Brüssel zufolge nicht ausreichend erklären, wie es zu den Lieferengpässen gekommen ist.

26.01.2021 - 12:22 [ Express.co.uk ]

German Health Ministry DENIES bombshell vaccine claims – says Berlin paper messed up stats

The health ministry insisted the claims made in German media last night were based on confused analysis of a study into the effectiveness of the AstraZeneca jab.

26.01.2021 - 12:18 [ Michaela Kuefner, hief Political Editor at DW, Germany's international TV channel / Twitter ]

In an exclusive interview with @dw_politics German health minister @jensspahn calls for a licensing requirement for the export of vaccines outside the EU. Given the state funds spent on building up production capacity this is not about EU “first, but fair” Spahn told me.

26.01.2021 - 11:52 [ Express.co.uk ]

‚F***ing bonkers!‘ UK attacks Germany over Oxford vaccine ‚lies‘ – EU row erupts

Another Westminster official said: “The efficacy claims circulating in the German media are unsubstantiated and incorrect.”

Speaking to Politico, a third added: “After this, support for Brexit will be at about 90 percent.”

The claims in the German media were made on the same day a row broke out between the European Union and AstraZeneca over supplies of the vaccine to the continent.

26.01.2021 - 11:29 [ Novasep.com ]

Coronavirus: NOVASEP partners with ASTRAZENECA to produce Covid-19 Oxford vaccine for Europe

(15.06.2020)

Novasep brings to AstraZeneca more than 20 years of expertise in viral vector production. Novasep’s investment strategy in the large-scale production of biopharmaceutical products for immunotherapy and gene therapy enables Novasep to support the alliance for the production of the vaccine active substance in Europe.

The production operations will be carried out at Novasep’s Belgian site in Seneffe. Furthermore, the biopharmaceutical ecosystem in the region allows Novasep to rapidly mobilize the additional human resources needed to achieve this project.

26.01.2021 - 11:01 [ DailyMail.co.uk ]

The great vaccine blockade? EU threat to cut off UK’s supply of Pfizer jabs will ‚poison relations for a generation‘ as Germans are accused of ‚Russian-style‘ disinformation over ‚rubbish‘ claim that AstraZeneca version is just 8% effective in elderly

Meanwhile, there is another row raging after two German newspapers claimed the EU’s regulator could refuse to give the Oxford/AstraZeneca jab full approval, with officials anonymously briefing its efficacy for pensioners was just eight per cent.

However, the claim was branded ‚absolutely incorrect‘ and ‚unsubstantiated‘ by the pharmaceutical company – and No10 sources told MailOnline it was ‚rubbish‘. One Whitehall source told Playbook it was the kind of tactics ‚you expect from the Russians‘.

26.01.2021 - 11:00 [ Tagesschau.de ]

Corona-Impfstoff von AstraZeneca: Zu wenig Impfdosen – zu geringe Wirksamkeit?

Möglicherweise wird es Einschränkungen bei der Anwendung des Impfstoffs geben, denn Zeitungsberichten zufolge ist die Wirksamkeit bei älteren Menschen eingeschränkt. AstraZeneca weist das zwar zurück, einen Gegenbeweis bleibt das Unternehmen in seinen Veröffentlichungen bisher aber schuldig.

26.01.2021 - 10:05 [ Stella Kyriakides, European Commissioner for Health and Food Safety / Twitter ]

With our Member States, we have requested from AZ a detailed planning of vaccine deliveries and when distribution will take place to Member States. Another meeting will be convened on Wednesday to discuss the matter further.

25.01.2021 - 20:25 [ Stella Kyriakides, European Commissioner for Health and Food Safety / Twitter ]

In addition, today we discussed with the 27 Member States in the Steering Board that an export transparency mechanism will be put in place as soon as possible. We want clarity on transactions and full transparency concerning the export of vaccines from the EU.

25.01.2021 - 20:20 [ EU Commission ]

Press statement by Commissioner Kyriakides on vaccine deliveries and on the vaccine export transparency scheme

Good evening.

You know that AstraZeneca’s vaccine is currently in the final stages of the approval process with the European Medicines Agency.

If all requirements are met, the European Medicines Agency could recommend market authorisation by the end of this week.

But there is a problem on the supply side.

Last Friday, the company AstraZeneca surprisingly informed the Commission and the European Union Member States that it intends to supply considerably fewer doses in the coming weeks than agreed and announced.

This new schedule is not acceptable to the European Union.

25.01.2021 - 20:02 [ South China Morning Post ]

Coronavirus: EU locks horns with AstraZeneca on vaccine deliveries amid ‘supply shock’

n a sign of the EU’s frustration – after Pfizer also announced a temporary slowdown in vaccine supplies earlier in January – EU health commissioner Stella Kyriakides proposed forcing drug makers to register in advance their Covid-19 vaccine exports, so the bloc can keep track of what they are doing.

25.01.2021 - 19:53 [ Tagesschau.de ]

Streit über Impfstoff: EU besteht auf zugesagte Lieferungen

In der ersten Gesprächsrunde zwischen AstraZeneca, Vertretern der EU-Kommission und den Mitgliedsländern gab es dem Vernehmen nach keine Fortschritte. Man hat die Positionen ausgetauscht. Es sei jedoch nicht sicher, ob AstraZeneca den Ernst der Lage verstanden hat, hieß es aus der Kommission. Am Abend soll eine zweite Gesprächsrunde folgen.

24.01.2021 - 06:10 [ theHindu.com ]

India clears vaccine exports to Brazil after delay

(21.01.2021)

Brazil is set to collect two million doses of Serum Institute’s (SII) Covishield vaccine, two weeks after Brazilian President Jair Bolsonaro requested Prime Minister Narendra Modi for their “urgent” clearance, sources confirmed to The Hindu.

24.01.2021 - 06:07 [ Livemint.com ]

South Africa authorities approve Serum Institute of India’s COVID-19 vaccine

(23.01.2021)

Health Minister Zweli Mkhize announced on Friday that the South African Health Products Regulatory Authority (SAHPRA) has granted approval to the SII, which is producing the vaccine in collaboration with the University of Oxford and AstraZeneca, to supply the drug to the country.

24.01.2021 - 06:00 [ ORF.at ]

Italien übt scharfe Kritik wegen Lieferengpässen

Gesundheitsminister Roberto Speranza habe nun das Management von AstraZeneca getroffen, die die Einschränkungen bei den Lieferungen bestätigten. „All das ist unannehmbar“, so Conte, der mit Klagen gegen die Pharmakonzerne drohte.

23.01.2021 - 11:00 [ Stella Kyriakides, European Commissioner for Health and Food Safety / Twitter ]

. @EU_Commission and Member States expressed deep dissatisfaction with this. We insisted on a precise delivery schedule on the basis of which Member States should be planning their vaccination programs, subject to the granting of a contitional marketing authorisation. /2

The @EU_Commission will continue to insist with @AstraZeneca on measures to increase predictability and stability of deliveries, and acceleration of the distribution of doses/3.

23.01.2021 - 10:39 [ Sky.com ]

COVID-19: AstraZeneca to ‚cut COVID-19 vaccine delivery to EU by 60%‘

The company was expected to deliver around 80 million doses to the 27 EU countries by the end of March, an EU official told the agency.

However, it now expects that to be cut to 31 million doses due to „production problems“ at a vaccine factory in Belgium run by its partner Novasep.

22.01.2021 - 19:08 [ ORF.at ]

AstraZeneca: Liefermengen niedriger als geplant

Grund dafür sind laut AstraZeneca „reduzierte Erträge der Impfsubstanz an einem Produktionsstandort“, hieß es. Insgesamt werde man im Februar und März „mehrere zehn Millionen Dosen“ in die EU liefern.

21.01.2021 - 12:57 [ Radio Utopie ]

Denkt Boris Johnson mit?

Wir berichteten am 4. Dezember, dass der bereits im Frühjahr 2020 von der Oxford Universität entwickelte Impfstoff ChAdOx1 nCoV-19 (später AZD1222 oder Covishield) „jederzeit allen weiteren Varianten“ von SARS II angepasst werden kann. Wie der britische „Telegaph“ nun berichtet, geschieht dies jetzt.

Premierminister Boris Johnson, ansonsten umflutet von Myraden von Experten und sicherlich auch privat als Daddy gefordert, soll sich nun ausnahmsweise mit den Wissenschaftler.innen der Oxford Universität „intensiv“ unterhalten.

Es wurde auch Zeit.

21.01.2021 - 09:54 [ ORF.at ]

Bericht: AstraZeneca-Impfstoff wird überarbeitet

Wissenschaftlerinnen und Wissenschaftler der Universität Oxford überarbeiten den zusammen mit dem Konzern AstraZeneca entwickelten CoV-Impfstoff, damit dieser gezielt gegen die neuen, hochansteckenden Coronavirus-Mutationen eingesetzt werden kann, die in Großbritannien, Südafrika und Brasilien entdeckt wurden.

21.01.2021 - 09:45 [ Telegraph.co.uk ]

Oxford scientists preparing new vaccine versions to combat emerging Covid strains

A laboratory study found that the 501Y.V2 variant achieved „complete escape“ from monoclonal antibodies, the man-made proteins that act like the antibodies produced by jabs.

Boris Johnson said he was holding „intensive talks“ with scientists about the new variants. The Prime Minister told MPs he was confident that the Medicines and Healthcare products Regulatory Agency (MHRA) was capable of approving new vaccine modifications as quickly as necessary.

16.01.2021 - 19:20 [ ABC News ]

India starts world’s largest COVID-19 vaccination drive

India on Jan. 4 approved emergency use of two vaccines, one developed by Oxford University and U.K.-based drugmaker AstraZeneca, and another by Indian company Bharat Biotech. Cargo planes flew 16.5 million shots to different Indian cities last week.

13.01.2021 - 17:57 [ theGuardian.com ]

How well does the Oxford vaccine work? What we know so far

(30.12.2020)

And while there are some early signs the Oxford/AstraZeneca vaccine might not only prevent people becoming seriously ill with Covid but also prevent asymptomatic infections, more data is needed to confirm such protection.

12.01.2021 - 14:35 [ Yahoo.com ]

China’s Kangtai starts mid-stage trial of its COVID-19 vaccine candidate

(29.10.2020)

Apart from developing its own vaccine, Kangtai also has a deal to make and supply mainland China with the vaccine candidate developed by AstraZeneca and researchers at the University of Oxford.

12.01.2021 - 14:28 [ New York Times ]

China’s ‘King of Vaccines,’ a partner to AstraZeneca, is plagued by scandal.

(Dec. 7, 2020)

Kangtai will be the exclusive manufacturer in mainland China for the vaccine made by AstraZeneca, and the companies could work together on deals for other countries. Kangtai is also in early trials for its own candidate.

12.01.2021 - 14:20 [ LSE.co.uk ]

UPDATE 1-Brazil’s Fiocruz says AstraZeneca vaccine ingredients may be delayed weeks

(08.01.2021)

A source with knowledge of the situation said the active
ingredient is ready to be shipped to Brazil, but is still
waiting for an export license from China, where it is produced.

12.01.2021 - 14:15 [ theHill.com ]

AstraZeneca vaccine likely won’t be authorized in US until April

(30.12.2020)

The coronavirus vaccine developed by AstraZeneca and Oxford University is not likely to be authorized for use in the U.S. until April, a top Trump administration health official said Wednesday.

“We project, if everything goes well, that the readout and emergency use authorization may be granted somewhere early in the month of April,” Moncef Slaoui, the chief science adviser for the administration’s Operation Warp Speed, told reporters.

12.01.2021 - 13:08 [ Ben Mulcahy / Twitter ]

AstraZ did not apply for approval until now. EMA cannot approve what they do not get.

(…)

12.01.2021 - 13:01 [ Ursula von der Leyen, President of the @EU_Commission / Twitter ]

Good news! @AstraZeneca has applied to @EMA_News to have its vaccine authorised in the EU. @EMA_News will assess the vaccine’s safety & efficacy.

Once the vaccine receives a positive scientific opinion, we will work full speed to authorise its use in Europe.

12.01.2021 - 12:54 [ KleineZeitung.at ]

Zulassung beantragt: EU-Entscheidung über Astrazeneca-Vakzine folgt noch im Jänner

Für die EU und Österreich soll der ChAdOx1 nCoV-19-Impfstoff mit 400 Millionen vorbestellten Dosen das Rückgrat für die Durchimpfung der breiten Bevölkerung darstellen. Das wird auch dadurch erleichtert, dass die Vakzine bei normaler Kühlschranktemperatur von zwei bis acht Grad Celsius länger aufbewahrt werden kann.

11.01.2021 - 08:14 [ DailyMal.co.uk ]

No 10 considers a tougher lockdown ‚with curfews, exercise limits, compulsory masks outside, no support bubbles and nurseries shut‘ if Covid cases keep rising‘ – amid suggestion ‚people may only be allowed to leave home ONCE a week‘

– The Cabinet Office refused to deny that the draconian new laws were incoming after UK’s streets were busy
– They instead pointed to Matt Hancock’s vague statement on rules earlier today: ‚Follow the rules we’ve got‘
– Hancock refused to speculate when asked if harsher measures coming, such as curfews and closing nurseries
– Whitehall source said potential changes included introducing ban on people leaving their homes more than once a week

10.01.2021 - 15:33 [ theGuardian.com ]

NHS could vaccinate UK against Covid in five days, says Oxford professor

Sir John Bell, regius chair of medicine at the University of Oxford, said stubborn NHS bureaucrats were standing in the way of a high-speed mass inoculation programme that could prevent many further deaths.

“The NHS has the theoretical capacity to immunise everybody in five days if they want to, but I don’t get the sense they are really motivated,” Bell told the Times.

06.01.2021 - 10:00 [ Ian Cornwell / Twitter ]

Ireland. Just had a 16 Billion Euro COVID bill, that it gets 1.5 back from. Waits patiently for the EMA to approve its vaccines. No sign of the EMA approving Oxford any time soon. 2009 – gets another Lisbon ref, whilst being threatened with perdition. „Independence“

06.01.2021 - 09:53 [ Giles Maybe / Twitter ]

EU land news. EMA who sign off vaccine has not even began to look at the AZ Oxford vaccine while its own curevac vaccine is still months away from approval. The eu failed to buy needles & its vaccine distributions hit a brick wall yesterday (accept holland They not yet started)

05.01.2021 - 08:22 [ Hindustan Times ]

Covid-19: UK begins immunisation drive of second vaccine, Mexico okays Oxford-AstraZeneca candidate

2. Mexico has approved the Oxford-AstraZeneca vaccine, its government announced on Monday, joining the UK, Argentina and India in giving a nod to the shot.

05.01.2021 - 08:19 [ NewsGhana.com.gh ]

Argentina and El Salvador approve AstraZeneca/Oxford Covid-vaccine

(31.12.2020)

Argentina has approved the coronavirus vaccine developed by Oxford University and the pharmaceutical company AstraZeneca, making it the second country after Britain to do so.

04.01.2021 - 17:17 [ Independent.co.uk ]

Matt Hancock blames Covid spread on public as government under pressure for new lockdown

Health secretary Matt Hancock has said that Boris Johnson’s tier system is “no longer strong enough” to deal with the new more virulent variant of coronavirus.

04.01.2021 - 07:37 [ DailyMail.co.uk ]

Operation Hope begins: Half a MILLION Covid-19 jabs will be made available to vulnerable people this week in UK’s biggest EVER mass vaccination drive as health bosses ramp up efforts to beat the pandemic

Elderly and infirm people in Oxford, London, Brighton, Morecambe in Lancashire and Nuneaton in Warwickshire are due to be first to receive the jab.

A total of 530,000 doses will be made available at 540 GP vaccination sites and 101 hospitals this week.

The NHS has ordered 100million doses which it is hoped will free the country from Covid-19.

04.01.2021 - 07:30 [ theSun.co.uk ]

First of 530,000 Oxford/AstraZeneca jabs to be rolled out today in Britain’s war on coronavirus

Hospitals at six NHS trusts across London, Brighton, Oxford, Morecambe and Nuneaton will be the first to give the vaccine.

It will reach more than 500 GP surgeries and community centres by the end of the week — with PM Boris Johnson saying “we are going as fast as we can”.

04.01.2021 - 07:28 [ theSun.co.uk ]

Amazing 7,750 volunteers sign up to The Sun’s Jabs Army appeal in first 48 hours

The Sun joined forces with the NHS and the Royal Voluntary Service to urge readers to volunteer as stewards at the pop-up vaccination centres across the UK. It launched on New Year’s Day.

According to the latest figures, 7,744 have signed up to help, with most of those crediting The Sun.

Catherine Johnstone CBE, chief exec of the Royal Voluntary Service, said: “The response from Sun readers has been incredible.

03.01.2021 - 08:08 [ Times of India ]

Global partnership COVAX secures two billion COVID-19 vaccine doses

(19.12.2020)

UNITED NATIONS: Global vaccine partnership COVAX has lined up almost two billion doses of existing and candidate COVID-19 vaccines for use worldwide, including 200 million doses of the AstraZeneca/Oxford vaccine through an agreement between the Vaccine Alliance Gavi, the Serum Institute of India and the Bill and Melinda Gates Foundation.

03.01.2021 - 06:56 [ DailyMail.co.uk ]

Boris Johnson hails Oxford vaccine as a ‚triumph for British science‘ and says he is ‚confident this is the year we will defeat coronavirus‘

The initial supplies of Oxford-AstraZeneca vaccine have been produced by a company called Halix in the Netherlands.

Once produced in bulk, the vaccine goes to a plant in Wrexham, run by an Indian company called Wockhardt, where it is decanted into vials in a process known as ‚fill and finish‘. The plant can bottle at least 150,000 doses a day.

02.01.2021 - 19:20 [ theSun.co.uk ]

First Oxford Covid vaccine doses arrive at UK hospitals with 530,000 jabs to be rolled out from Monday

While the Oxford vaccine uses a harmless, weakened version of a common virus in chimpanzees, the Pfizer jab is known as a messenger vaccine (MRNA), using a genetic code rather than a weakened form of the virus.

And experts have urged patients not to mix and match the two.

02.01.2021 - 19:11 [ ORF.at ]

EU-Kommissarin verteidigt Impfstrategie

Gleichzeitig habe man mit anderen Herstellern Verträge geschlossen. „Wir waren uns in der EU einig, dass wir nicht alles auf eine Karte setzen dürfen“, so die Kommissarin. Sonst wären die EU-Staaten womöglich ohne wirksamen Impfstoff dagestanden.

02.01.2021 - 19:06 [ DailyMail.co.uk ]

EU bureaucracy is accused of ‚costing lives‘ after European regulators said they cannot approve the Oxford vaccine before February

(31.12.2020)

Mr Wathion told Belgian newspaper Het Nieuwsblad the EMA was ‘in the dark’ about what kind of data was being used for Britain to approve the use of the Oxford vaccine.

The EU has already bought 400million doses of the jab while awaiting regulatory approval.

02.01.2021 - 14:59 [ news.com.au ]

Why no jab? Australia lags behind in race for vaccine

Despite assurances by Health Minister Greg Hunt that the progression of the vaccine was well under way, the Australian Government is unlikely to start immunising health workers and the elderly until at least March.

02.01.2021 - 14:56 [ SBS.com.au ]

AstraZeneca vaccine could get approval in Australia by late January

(31.12.2020)

The Australian government could grant final approval for the AstraZeneca/Oxford vaccine by late January, according to AstraZeneca Australia.

A spokesperson for the company told SBS World News that the federal government has indicated the vaccine could get final approval by January 31, with a roll out in March.

02.01.2021 - 08:32 [ .business-live.co.uk ]

Wrexham factory to produce millions of doses of the Oxford/AstraZeneca vaccine

(30.12.2020)

The Wrexham plant is able to produce around 300 million doses of the vaccine each year, and has been producing 150,000 phials a day for months in readiness to roll out the vaccine across the UK.

The CP Pharmaceuticals lab will carry out the „fill and finish“ stage of the manufacturing process. This involves dispensing the vaccine into vials ready for it to be sent out across the country.

The 18-month agreement with parent company Wockhardt was announced back in August.

02.01.2021 - 08:21 [ IndiaToday.in ]

Oxford Covid-19 vaccine Covishield gets emergency use approval in India

An expert panel on Covid-19 of the Central Drugs Standard Control Organisation (CDSCO) on Friday granted emergency use authorisation for the Oxford Covid-19 vaccine Covishield, being manufactured by Serum Institute of India, sources said on Friday.

01.01.2021 - 08:55 [ Radio Utopie ]

Wie die Briten mit der neuen Totalen Weltordnung brechen und die Aufhebung des Ausnahmezustands feiern könnten

Ich sage nicht, dass das passieren wird. Ich sage – sie könnten.

Stellt es Euch vor…

01.01.2021 - 08:50 [ Firstpost.com ]

EU still holds out on granting approval to Oxford-AstraZeneca’s COVID-19 vaccine

„Additional scientific information on issues related to quality, safety and efficacy of the vaccine is deemed necessary to support the rigour required for a conditional marketing authorisation (CMA) and this has been requested from the company,“ the EMA said in a statement. „Further information from the ongoing clinical trials is also expected from January.“

The Amsterdam-based agency earlier told AFP that it had not yet received any formal marketing authorisation and that it had set no timetable for approving the vaccine.

31.12.2020 - 06:48 [ DailyMail.co.uk ]

PROFESSOR ANGUS DALGLEISH: The Oxford AstraZeneca coronavirus vaccine is as close to a miracle as medicine ever gets

Everyone can see what a serious emergency this is. We have to act. Bin the bureaucracy, and get this miracle vaccine to work right now.

31.12.2020 - 05:26 [ theGuardian.com ]

How well does the Oxford vaccine work? What we know so far

And while there are some early signs the Oxford/AstraZeneca vaccine might not only prevent people becoming seriously ill with Covid but also prevent asymptomatic infections, more data is needed to confirm such protection.

30.12.2020 - 17:39 [ New York Times ]

U.K. Authorizes Covid-19 Vaccine From Oxford and AstraZeneca

A decision is further off in the United States, where the Food and Drug Administration is waiting for data from a separate clinical trial. The study was halted in September and delayed for nearly seven weeks — much longer than in other countries — as regulators investigated whether an illness in a participant in Britain was related to the vaccine. American regulators ultimately allowed the trial to proceed.

30.12.2020 - 16:16 [ Boris Johnson, Prime Minister of the United Kingdom / Twitter ]

It is truly fantastic news – and a triumph for British science – that the @UniofOxford /@AstraZeneca vaccine has been approved for use. We will now move to vaccinate as many people as quickly as possible.

30.12.2020 - 12:24 [ AstraZeneca.com ]

AstraZeneca and Oxford University announce landmark agreement for COVID-19 vaccine

(30.04.2020)

The collaboration aims to bring to patients the potential vaccine known as ChAdOx1 nCoV-19, being developed by the Jenner Institute and Oxford Vaccine Group, at the University of Oxford. Under the agreement, AstraZeneca would be responsible for development and worldwide manufacturing and distribution of the vaccine.

30.12.2020 - 12:14 [ thehindubusinessline.com ]

AstraZeneca’s Covid-19 vaccine may have to wait for EU’s approval

The EMA’s deputy executive director Noel Wathion told Belgian newspaper Het Nieuwsblad that the pharmaceutical company “has not even filed an application” with the European drug regulators yet.

He further said that EMA “did not even have enough to warrant a conditional marketing license.”

30.12.2020 - 11:55 [ ntv Nachrichten / Twitter ]

Wohl keine Zulassung im Januar: EMA: Astrazeneca hat noch nichts beantragt

30.12.2020 - 11:06 [ ABC.net.au ]

Australia locks in coronavirus vaccine deal to produce Oxford University-AstraZeneca candidate if approved

(18 August 2020)

Amid rising pressure to lock in supply of a coronavirus vaccine, the Government has signed an agreement with UK-based drug company AstraZeneca to secure the potential COVID-19 vaccine developed by Oxford University, if its trials prove successful.

30.12.2020 - 11:00 [ Sydney Morning Herald ]

AstraZeneca/Oxford COVID-19 vaccine approved in Britain

Australia has secured 53.8 million doses of the Oxford vaccine, most of which could be manufactured locally by CSL. The federal government has also ordered 10 million doses of the Pfizer vaccine, which will all have to be imported.

Federal Health Minister Greg Hunt said on Monday he expects Australia to be „fully vaccinated“ against coronavirus by October next year.

30.12.2020 - 10:53 [ zeenews.india.com ]

COVID-19: UK approves use of AstraZeneca-Oxford vaccine, all eyes on India now

The approval by UK government is a good news for India because as per sources, the government was waiting for this approval and it is expected that Indian regulators would call SEC meet soon and reconsider the data and approve AstraZeneca vaccine for its use in India.

30.12.2020 - 10:09 [ UK Department of Health and Social Care / UK Medicines and Healthcare Products Regulatory Agency ]

Oxford University/AstraZeneca vaccine authorised by UK medicines regulator

The Government has today accepted the recommendation from the Medicines and Healthcare products Regulatory Agency (MHRA) to authorise Oxford University/AstraZeneca’s Covid-19 vaccine for use.

30.12.2020 - 10:05 [ BBC ]

Covid-19: Oxford-AstraZeneca coronavirus vaccine approved for use in UK

The Oxford-AstraZeneca vaccine has been approved for use in the UK, with the first doses due to be given on Monday amid rising coronavirus cases.

30.12.2020 - 03:58 [ mark cording / Twitter ]

What’s the update on the Oxford vaccine Mr Hancock

30.12.2020 - 03:50 [ Matt Hancock, secretary of State for Health & Social Care / Twitter ]

Fantastic to see Margaret Keenan receive her second dose of the @Pfizer /@BioNTech_Group #coronavirus vaccine

30.12.2020 - 03:38 [ BBC ]

Covid: Millions more braced for tougher rules in England

Government sources have indicated an announcement later will see more areas move into tier four – „stay at home“.

Health Secretary Matt Hancock is due to detail the changes – which could be introduced within days – in the House of Commons after 14:30 GMT.

30.12.2020 - 03:35 [ noone@nowhere / Twitter ]

Still no Oxford vaccine emergency approval. Unbelievable.

(23.12.2020)

28.12.2020 - 17:26 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

28.12.2020 - 17:25 [ Telegraph.co.uk ]

Coronavirus latest news: One million vaccinations a week will not bring pandemic under control, warns Sage expert

Sir Jeremy Farrar, the director of the Wellcome Trust who advises Number 10’s advisory panel Scientific Advisory Group for Emergencies (Sage) said: „We’re not going to be free of this pandemic by February, this is now a human endemic infection.

28.12.2020 - 17:24 [ .oxfordmail.co.uk ]

No herd immunity through vaccine programme before summer, Sage scientist warns

Calum Semple, professor of outbreak medicine at the University of Liverpool and a member of the Scientific Advisory Group for Emergencies (Sage), described the Oxford/AstraZeneca vaccine as a “game changer” if it is approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the coming days.

But he told BBC Breakfast…

28.12.2020 - 09:24 [ Telegraph.co.uk ]

Oxford coronavirus vaccine: 10,000 medics and volunteers recruited to administer jab

The Oxford/AstraZeneca jab could be approved early next week by the independent Medicines and Healthcare products Regulatory Agency (MHRA), after the final cut of data was submitted by the Government last Monday.

28.12.2020 - 05:18 [ noone@nowhere / Twitter ]

Still no Oxford vaccine emergency approval. Unbelievable.

(23.12.2020)

27.12.2020 - 11:09 [ DailyMail.co.uk ]

Britain could be free of Covid restrictions by February after ministers pinpointed the 15million people to vaccinate to end the cycle of lockdowns, with Oxford’s jab due to be approved Monday and rolled out within a week

Government sources say that between 12 million and 15 million people have been identified as likely to require hospital treatment if they contract coronavirus, or be at risk of dying from it. Once this group has received the vaccine – which some officials hope could be achieved by the end of February – then the NHS would no longer be at risk of being overwhelmed if the virus spread through the greater population. That would remove the main argument for shutting the economy at a stroke.

A source said: ‚The path to liberation is finally becoming clear.‘

27.12.2020 - 11:02 [ theSun.co.uk ]

‚THE BEST OF BRITISH‘: Oxford Covid vaccine expected to be approved MONDAY as huge efforts ‘pay off’

„We have seen the best of British at every stage, from our world-leading scientists working around the clock to carry out vital research, to builders and engineers constructing new facilities.

“Manufacturers are boosting their capabilities and hundreds of thousands of people in every corner of the UK are taking part in clinical trials ­­— developing, finding and preparing for a vaccine has involved us all.

“It has and continues to be a truly UK-wide effort and one which showcases what a fantastic nation we are.”

27.12.2020 - 05:22 [ gab.ai/murali / Twitter ]

How many willing to bet that this case is part of pharma wars to sabotage Oxford vaccine?

(28.11.2020)

27.12.2020 - 05:20 [ Sean / Twitter ]

Can I ask why the Oxford vaccine approval is taking so long? It only took 23 days for Pfizers, we are nearly at day 30 and still no sign of approval!

(21.12.2020)

27.12.2020 - 05:05 [ Telegraph.co.uk ]

Millions to receive Oxford coronavirus vaccine from Jan 4

The Government is aiming for two million people to receive their first dose of either the Oxford vaccine or the Pfizer jab within a fortnight as part of a major ramping up of the inoculation programme.

23.12.2020 - 11:32 [ BBC ]

Oxford vaccine: How did they make it so quickly?

(23.11.2020)

Scientists took a common cold virus that infected chimpanzees and engineered it to become the building block of a vaccine against almost anything.

Before Covid, 330 people had been given ChAdOx1 based-vaccines for diseases ranging from flu to Zika virus, and prostate cancer to the tropical disease chikungunya.

The virus from chimps is genetically modified so it cannot cause an infection in people. It can then be modified again to contain the genetic blueprints for whatever you want to train the immune system to attack.

23.12.2020 - 11:18 [ inews.co.uk ]

Boris Johnson’s future as Prime Minister rests on the Oxford vaccine being approved

The hope in Downing Street is that the Oxford vaccine will get the green light by the end of the year. This would allow the Prime Minister to start laying out plans for restrictions to be lifted.

23.12.2020 - 11:13 [ Times of India ]

India likely to approve AstraZeneca vaccine by next week

India is likely to approve Oxford/AstraZeneca’s coronavirus vaccine for emergency use by next week after its local manufacturer submitted additional data sought by authorities, two sources with knowledge of the matter told Reuters on Tuesday.

21.12.2020 - 22:37 [ DailyMail.co.uk ]

UK has vaccinated 500,000 people against Covid since December 8, Boris Johnson says as regulators face growing pressure to approve Oxford’s jab in desperate race to speed up the roll-out

The MHRA drugs regulator has been doing its final review of the vaccine for three weeks now, since November 27, with a decision expected by next Tuesday.

(…)

However, they made a decision about Pfizer and BioNTech’s jab within 10 days of being instructed to do so by the Department of Health.

20.12.2020 - 10:10 [ theGuardian.com ]

Oxford vaccine still under review, says UK medicine agency

But Whitehall sources said that while they hoped the vaccine would be available that week, it was by no means certain, and the authorisation could be delayed until the beginning of January.

The delay has caused frustration in Whitehall and the NHS, with the vaccine taking much longer to meet approval than the Pfizer vaccine, which was rolled out in the UK last week.

12.12.2020 - 20:01 [ NBC News ]

Scientist behind Oxford vaccine urges FDA not to delay data review

Professor Adrian Hill, part of the team behind the Oxford-AstraZeneca Covid-19 vaccine, says he hopes the FDA will review the available data in January, because waiting for the trial’s end next year would be “too late.”

12.12.2020 - 20:00 [ CNN ]

It took AstraZeneca researchers 1 month to get vaccine trial data to FDA, source tells CNN

(14.10.2020)

The source said the root of the delay is that the participant was in the United Kingdom, and the European Medicines Agency and the FDA store data differently.

„They had to convert data from one format to another format. It’s like taking stuff off a PC and putting it onto an Apple. They had to spend a lot of hours to get what they wanted,“ the source said.

12.12.2020 - 19:43 [ New York Times ]

Blunders Eroded U.S. Confidence in Early Vaccine Front-Runner

AstraZeneca was in part to blame for the delay, said the people with knowledge of the F.D.A. talks. The company was slow to provide the F.D.A. with all the data that regulators wanted to review before allowing the trial to start up again.

In late October, after 47 days, the F.D.A. cleared the U.S. trial to restart.

It was now even further behind the late-stage trials that Pfizer and Moderna had begun in the United States about a month before AstraZeneca’s trial started.

09.12.2020 - 20:31 [ Standard.co.uk ]

How does Oxford University’s coronavirus vaccine work and how is it different to Pfizer and Moderna’s?

Does it differ to PFizer and Moderna’s vaccines?

Yes. The jabs from Pfizer and Moderna are messenger RNA (mRNA) vaccines.

Conventional vaccines are produced using weakened forms of the virus, but mRNAs use only the virus’s genetic code.

08.12.2020 - 18:13 [ University of Oxford ]

First peer-reviewed results of phase 3 human trials of Oxford coronavirus vaccine demonstrate efficacy

. These data indicate that the low dose / standard dose vaccine may provide a protection against asymptomatic infection, but stress that these data are at an early phase, with too high a level of uncertainty to be certain that this vaccine will protect against asymptomatic infection.

08.12.2020 - 18:12 [ theLancet.com ]

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

ChAdOx1 nCoV-19 appears to be better tolerated in older adults than in younger adults and has similar immunogenicity across all age groups after a boost dose.

08.12.2020 - 18:11 [ DailyMail.co.uk ]

Oxford confirms its Covid vaccine is 70% effective and safe – but scientists warn regulators face ‚dilemma‘ in approving jab to be given as 1.5 doses (which they accidentally found is 90% protective)

The MHRA has been considering whether to approve the vaccine since November 27 and is expected to reach a decision before the end of the year.

02.12.2020 - 15:25 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

(23.11.2020)

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

01.12.2020 - 12:19 [ fiercepharma.com ]

AstraZeneca CEO blames trial delays, not manufacturing, for COVID-19 vaccine delivery shortfall

In fact, AZ has already produced a bulk vaccine that’s kept at freezing temperatures.

01.12.2020 - 12:12 [ Yahoo.com ]

Delivery timetable for Oxford/AstraZeneca vaccine slips, UK official says

UK Vaccine Taskforce Chair Kate Bingham said that the vaccine was being made in bulk first, known as „drug substance“, but could not yet be put into vials until more was known on the timing of late-stage trial data.

„We’ve not yet put them into vials because as soon as you put them into vials you start the clock for the… shelf life, or how quickly you have to use the vaccine,“ she told lawmakers.

23.11.2020 - 17:15 [ DailyMail.co.uk ]

‚I’m so thrilled that you’ve cracked it!‘: Prince William congratulates Oxford scientists via Zoom as their Covid vaccine is proved to be 90 per cent effective

– The Duke of Cambridge hailed the team’s ‚amazing achievement‘ this morning
– Three Oxford professors told how the vaccine is based on decades of research
– It emerged this month that William caught coronavirus in April but didn’t reveal it

23.11.2020 - 17:11 [ Politico.com ]

AstraZeneca to seek FDA authorization for vaccine based on foreign trial data

The company halted its U.S. trial in early September over safety concerns, after a trial participant reported neurological problems. The study resumed earlier this month after FDA concluded that no evidence linked the volunteer’s symptoms to the shot.

23.11.2020 - 17:04 [ Telegraph.co.uk ]

AstraZeneca shares slip after analyst says vaccine will struggle to get green light in US – live updates

SVB Leerink analyst Geoffrey Porges said the treatment may never gain approval from US regulator the FDA, and said Astra had highlighted results from a “relatively small” number of patients.

23.11.2020 - 16:40 [ theGuardian.com ]

Oxford AstraZeneca Covid vaccine: everything we know so far

No mRNA vaccine has ever been approved by regulators, but the Oxford approach has been used in vaccines given safely to thousands of people of all ages for diseases ranging from TB and malaria to Mers (another coronavirus) and Ebola, for which it is now being used in Uganda and the Democratic Republic of the Congo. Oxford opted for the chimp virus because it has the potential to generate a strong immune response and, since it cannot grow in humans, it should be safe.

Two other frontrunner vaccines, from BioNTech (developed with Pfizer) and Moderna (developed with the US National Institute of Allergy and Infectious Diseases), perform well, according to interim results from phase 3 human trials, achieving more than 90% efficacy. These are based on technology that is new to the vaccine field. Both use genetic material called mRNA, or messenger RNA, which tells human cells how to make coronavirus spike proteins.

23.11.2020 - 16:23 [ Tagesschau.de ]

Studienergebnisse von AstraZeneca: Britischer Impfstoff wirkt zu 70 Prozent

Das Ergebnis bleibt zwar hinter den Werten der Präparate von Pfizer/Biontech und Moderna zurück. Wenn man aber zunächst nur eine halbe Dosis verabreiche und erst einen Monat später eine volle, dann erreiche der Impfstoff eine Effektivität von 90 Prozent, lässt AstraZeneca wissen. Er soll zudem deutlich preiswerter sein, sich sehr viel leichter lagern und weltweit transportieren lassen als andere Vakzine.

23.11.2020 - 16:15 [ University of Oxford ]

Oxford University breakthrough on global COVID-19 vaccine

he University of Oxford, in collaboration with AstraZeneca plc, today announces interim trial data from its Phase III trials that show its candidate coronavirus vaccine, ChAdOx1 nCoV-2019, is effective at preventing COVID-19 (SARS-CoV-2) and offers a high level of protection.

16.11.2020 - 13:40 [ ChronicleLive.co.uk ]

UK’s Covid-19 Oxford AstraZeneca vaccine on course to be ready by end of 2020

The UK has ordered 100 million doses of the Oxford AstraZeneca vaccine – enough for the entire population

12.11.2020 - 11:12 [ HeraldScotland.com ]

Top Scots academic warns ministers not to prioritise Pfizer vaccine

The vaccine, which is thought to be effective against Covid-19 in nine out of 10 people, could be ready for distribution by next month but it needs to be stored at -80C for it to work.

This ‚ultra-cold‘ state is part of the logistical challenge facing the country, particularly if the vaccine is manufactured overseas.

The professor, from the university’s Centre for Sustainable Road Freight, explained that it may make more sense to prioritise the AstraZenica Oxford vaccine which can be made in the UK.

12.11.2020 - 11:09 [ Mark Sanders / Twitter ]

So the Pfizer vaccine is expected to be up to seven times more expensive than the Oxford one, reports the Times.

Welcome to profit first, morals later America.

12.11.2020 - 11:01 [ eastdevonwatch.org ]

Oxford v Pfizer: how costs and logistics could still see Oxford’s vaccine win out

Matt Hancock has warned the mass distribution would be a “colossal exercise” involving not just the NHS but the Armed Forces.

The Health Secretary acknowledged there was “enormous complexity” in administering the Pfizer vaccine.

10.11.2020 - 17:39 [ Brian / Twitter ]

Oxford vaccine is not mRNA based its DNA based. This is prolly the best description right now:

07.11.2020 - 14:53 [ University of Oxford ]

The Oxford Vaccine

The University of Oxford’s Jenner Institute and Oxford Vaccine Group have been at the forefront of scientific endeavour to develop vaccines for diseases of major global importance for more than 30 years.

Their ChAdOx1 trials are currently assessing whether the vaccine will be effective in combatting COVID-19.